Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 103486845

GI number: 103486845

Start: 1416274

End: 1417461

Strand: Reverse

Name: argD [H]

Synonym: Sala_1359

Alternate gene names: 103486845

Gene position: 1417461-1416274 (Counterclockwise)

Preceding gene: 103486846

Following gene: 103486844

Centisome position: 42.37

GC content: 64.56

Gene sequence:

>1188_bases
ATGTCGATCACGCCGCTCATGCCCGTATACCCCCGGTGCGCTGTGCGTCCGGTGCGCGGCGAGGGCGCCTATCTGATCGG
CGAGCGTGGCGAGCGCTATCTCGATTTTGCGAGCGGCATTGCGGTCAACCTGCTCGGCCACGGCCATCCGCATCTGACCA
GGGCGATTCAGGATCAGGCGGCGACGCTGATGCACGTGTCGAACCTTTATGGCAGCCCGCAGGGCGAAGCCTTTGCCCAG
CGGCTGGTCGACAACACCTTTGCCGACACCGTCTTTTTCACCAATTCGGGCGCCGAAGCGGTCGAATGCGCGATCAAGAC
CGCGCGCGCCTATCATTCGAGCGCGGGCAACGCCGAAAAACATAATCTCATCACCTTCAACAACGCCTTTCACGGCCGCA
CGCTCGGCACGATTTCGGCGACCAATCAGGAAAAGCTGCGCAAGGGGTTCGACCCGCTGCTGCCCGGCTTCGCCTATGCG
CCGTTCGACGACCTCAACGCCGCGCTCGACCTCGTCGACGACAATACGGCGGGCTTCCTCATCGAGCCGGTGCAGGGCGA
GGGCGGCATTCGCCCGGCGTCGCAGCCCTTCCTCCAGGGGCTGCGCGACATCTGCAACGAACGCGACCTGATGCTCATTT
TCGACGAGGTCCAGTGTGGCGTCGCGCGCACGGGCACGCTCTATGCCTATGAGCAGTACGGAATCGCGCCCGACATCATG
GCGACCGCGAAGGGTATCGGCGGCGGTTTCCCGCTCGGCGCGTGCCTTGCGACCGAAAAGGCGGCGCGCGGCATGGTGAT
CGGCACGCACGGATCGACCTATGGCGGAAATCCGCTCGCGATGGCGGCGGGGCAGGCGGTGTTCGACGTCATCCTGGAGG
ACGGATTTCTTGATCAGGTCAAGGCAACCGGCGAGCGGCTGCGCGGCGCGCTCGAACAGCTTATCCCCAACCACGACCAG
CTTTTTGAAAGCGTGCGCGGCATGGGACTGATGCTCGGCGTCAAGATGCGCTCGGACAGCCGTGCCTTCGTCGCGCACCT
GCGCGACAATCACGGGCTCCTGACCGTCGCGGCGGGCGACAATGTCGTGCGTATCCTGCCGCCGCTCAACATCGAGCAGG
GCCATATCGACGAGTGTATCGAGAAATTGTCGGCAGGCGCGGCGAGCTACACGCCGCCCGAAGCATGA

Upstream 100 bases:

>100_bases
CCGTGTTGACGCGCCTCCGGCACCGGCAGTATAGGAGCGGCCCGACCAAGGGCGGCCCGAACGGGGTCGCCTTTTACTTT
TTGACTGAAAGGTGCCTGCC

Downstream 100 bases:

>100_bases
TTTTCGTTGTTCCGTTCGTGTCGAGCGAAGTCGAGACACCCAATGGCAGCGCGCGAACTCACGGCATCTCGACTTCGCTC
GATGCGAACGGGGAGGTAAT

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSITPLMPVYPRCAVRPVRGEGAYLIGERGERYLDFASGIAVNLLGHGHPHLTRAIQDQAATLMHVSNLYGSPQGEAFAQ
RLVDNTFADTVFFTNSGAEAVECAIKTARAYHSSAGNAEKHNLITFNNAFHGRTLGTISATNQEKLRKGFDPLLPGFAYA
PFDDLNAALDLVDDNTAGFLIEPVQGEGGIRPASQPFLQGLRDICNERDLMLIFDEVQCGVARTGTLYAYEQYGIAPDIM
ATAKGIGGGFPLGACLATEKAARGMVIGTHGSTYGGNPLAMAAGQAVFDVILEDGFLDQVKATGERLRGALEQLIPNHDQ
LFESVRGMGLMLGVKMRSDSRAFVAHLRDNHGLLTVAAGDNVVRILPPLNIEQGHIDECIEKLSAGAASYTPPEA

Sequences:

>Translated_395_residues
MSITPLMPVYPRCAVRPVRGEGAYLIGERGERYLDFASGIAVNLLGHGHPHLTRAIQDQAATLMHVSNLYGSPQGEAFAQ
RLVDNTFADTVFFTNSGAEAVECAIKTARAYHSSAGNAEKHNLITFNNAFHGRTLGTISATNQEKLRKGFDPLLPGFAYA
PFDDLNAALDLVDDNTAGFLIEPVQGEGGIRPASQPFLQGLRDICNERDLMLIFDEVQCGVARTGTLYAYEQYGIAPDIM
ATAKGIGGGFPLGACLATEKAARGMVIGTHGSTYGGNPLAMAAGQAVFDVILEDGFLDQVKATGERLRGALEQLIPNHDQ
LFESVRGMGLMLGVKMRSDSRAFVAHLRDNHGLLTVAAGDNVVRILPPLNIEQGHIDECIEKLSAGAASYTPPEA
>Mature_394_residues
SITPLMPVYPRCAVRPVRGEGAYLIGERGERYLDFASGIAVNLLGHGHPHLTRAIQDQAATLMHVSNLYGSPQGEAFAQR
LVDNTFADTVFFTNSGAEAVECAIKTARAYHSSAGNAEKHNLITFNNAFHGRTLGTISATNQEKLRKGFDPLLPGFAYAP
FDDLNAALDLVDDNTAGFLIEPVQGEGGIRPASQPFLQGLRDICNERDLMLIFDEVQCGVARTGTLYAYEQYGIAPDIMA
TAKGIGGGFPLGACLATEKAARGMVIGTHGSTYGGNPLAMAAGQAVFDVILEDGFLDQVKATGERLRGALEQLIPNHDQL
FESVRGMGLMLGVKMRSDSRAFVAHLRDNHGLLTVAAGDNVVRILPPLNIEQGHIDECIEKLSAGAASYTPPEA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=381, Percent_Identity=32.5459317585302, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI284507298, Length=304, Percent_Identity=33.5526315789474, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=28.175519630485, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI37574042, Length=403, Percent_Identity=27.0471464019851, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=27.1634615384615, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI226442705, Length=403, Percent_Identity=26.5508684863524, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=25.3623188405797, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=25.3623188405797, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=25.3623188405797, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226442709, Length=373, Percent_Identity=26.5415549597855, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=44.7570332480818, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=40.7216494845361, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=35.1758793969849, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI145693181, Length=369, Percent_Identity=33.8753387533875, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787560, Length=410, Percent_Identity=33.9024390243902, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1786991, Length=356, Percent_Identity=33.9887640449438, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786349, Length=327, Percent_Identity=30.2752293577982, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=368, Percent_Identity=32.6086956521739, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI32564660, Length=452, Percent_Identity=28.7610619469027, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=255, Percent_Identity=32.9411764705882, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=29.0780141843972, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541228, Length=425, Percent_Identity=25.8823529411765, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71981843, Length=179, Percent_Identity=30.1675977653631, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=374, Percent_Identity=37.1657754010695, Blast_Score=259, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6323470, Length=387, Percent_Identity=30.749354005168, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=342, Percent_Identity=26.9005847953216, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=427, Percent_Identity=27.8688524590164, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21357415, Length=371, Percent_Identity=33.4231805929919, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI28574759, Length=409, Percent_Identity=30.0733496332518, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI161085790, Length=421, Percent_Identity=29.2161520190024, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21356575, Length=411, Percent_Identity=28.4671532846715, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=25.1196172248804, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=25.1196172248804, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=25.1196172248804, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42240; Mature: 42109

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITPLMPVYPRCAVRPVRGEGAYLIGERGERYLDFASGIAVNLLGHGHPHLTRAIQDQA
CCCCCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHH
ATLMHVSNLYGSPQGEAFAQRLVDNTFADTVFFTNSGAEAVECAIKTARAYHSSAGNAEK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
HNLITFNNAFHGRTLGTISATNQEKLRKGFDPLLPGFAYAPFDDLNAALDLVDDNTAGFL
CCEEEECCCCCCCEEEEEECCCHHHHHCCCCHHCCCCCCCCHHHHHHHEEEECCCCCCEE
IEPVQGEGGIRPASQPFLQGLRDICNERDLMLIFDEVQCGVARTGTLYAYEQYGIAPDIM
EEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEHHCCCCHHHH
ATAKGIGGGFPLGACLATEKAARGMVIGTHGSTYGGNPLAMAAGQAVFDVILEDGFLDQV
HHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
KATGERLRGALEQLIPNHDQLFESVRGMGLMLGVKMRSDSRAFVAHLRDNHGLLTVAAGD
HHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEEECCCCEEEEECCC
NVVRILPPLNIEQGHIDECIEKLSAGAASYTPPEA
CEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SITPLMPVYPRCAVRPVRGEGAYLIGERGERYLDFASGIAVNLLGHGHPHLTRAIQDQA
CCCCCCCCCCCCCEEEECCCCCEEECCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHHH
ATLMHVSNLYGSPQGEAFAQRLVDNTFADTVFFTNSGAEAVECAIKTARAYHSSAGNAEK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCC
HNLITFNNAFHGRTLGTISATNQEKLRKGFDPLLPGFAYAPFDDLNAALDLVDDNTAGFL
CCEEEECCCCCCCEEEEEECCCHHHHHCCCCHHCCCCCCCCHHHHHHHEEEECCCCCCEE
IEPVQGEGGIRPASQPFLQGLRDICNERDLMLIFDEVQCGVARTGTLYAYEQYGIAPDIM
EEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEHHCCCCHHHH
ATAKGIGGGFPLGACLATEKAARGMVIGTHGSTYGGNPLAMAAGQAVFDVILEDGFLDQV
HHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
KATGERLRGALEQLIPNHDQLFESVRGMGLMLGVKMRSDSRAFVAHLRDNHGLLTVAAGD
HHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEEECCCCEEEEECCC
NVVRILPPLNIEQGHIDECIEKLSAGAASYTPPEA
CEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]