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The map label for this gene is hfq [H]

Identifier: 103486758

GI number: 103486758

Start: 1328059

End: 1328649

Strand: Reverse

Name: hfq [H]

Synonym: Sala_1272

Alternate gene names: 103486758

Gene position: 1328649-1328059 (Counterclockwise)

Preceding gene: 103486759

Following gene: 103486757

Centisome position: 39.72

GC content: 56.35

Gene sequence:

>591_bases
TTGCCGCATATTGCGAGCAAGAAGAAGGTCTTGAAAGCCGGAAAACCGGCGCCGTGTCCGCGGTTTCACCGCCAAGAACA
GGAGGCAAATGTGTCCGATAAAAATCAGAATCTTCAGGATATTTTCCTCAACGCTCTCCGTAAAAGTAAAACCCCGGTCA
CGATGTTTCTCGTCAAGGGGGTCAAGCTTCAGGGCATCATCACCTGGTTCGACAATTTCTCGCTGCTGCTACGGCGCGAC
GGCCAGTCGCAACTGGTGTACAAGCACGCGATTTCGACCGTGATGCCTTCGCATGATTTCGACCTGTCGCTGCTCGGCGG
CAACCTGCGCGACGCGCCGGCGAGCAAGGGCAAAGCGCTGCAGGATGTATTCCTCAACGCCGTTCGTCGCTCGGATGAGT
CGGTGACGATGTTCCTCGTCAACGGCGTCATGTTGCAGGGCGACATTGTGGCATTCGACCTGTTCTGCATGTTGCTCGAA
CGTGAGCGACAGGTCCAGCTTGTTTACAAGCACGCGATTTCGACGGTCCAGCCCAACGGTCCCATCAACCTGACCGACAA
TGGCGACGACGAAGCGGCGGAAGACAGCTGA

Upstream 100 bases:

>100_bases
GCATGGAGCGCTCGGCGCTGCACCGCAAACTGAAACTTTTGGGGCTCACCGAAAGTTCGGATAATGAAAGTCCGGCTTGA
CGCTGGACGGTAGGTGCGCT

Downstream 100 bases:

>100_bases
TCGACCCGTTAGTCACTAGCGAAGACGAGGTTACGCGCGGCACGGCCGCGATGATTATCGTGCCCGAATGGCATGGCCAG
CGCCTTGCCCGCGACCTCGA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MPHIASKKKVLKAGKPAPCPRFHRQEQEANVSDKNQNLQDIFLNALRKSKTPVTMFLVKGVKLQGIITWFDNFSLLLRRD
GQSQLVYKHAISTVMPSHDFDLSLLGGNLRDAPASKGKALQDVFLNAVRRSDESVTMFLVNGVMLQGDIVAFDLFCMLLE
RERQVQLVYKHAISTVQPNGPINLTDNGDDEAAEDS

Sequences:

>Translated_196_residues
MPHIASKKKVLKAGKPAPCPRFHRQEQEANVSDKNQNLQDIFLNALRKSKTPVTMFLVKGVKLQGIITWFDNFSLLLRRD
GQSQLVYKHAISTVMPSHDFDLSLLGGNLRDAPASKGKALQDVFLNAVRRSDESVTMFLVNGVMLQGDIVAFDLFCMLLE
RERQVQLVYKHAISTVQPNGPINLTDNGDDEAAEDS
>Mature_195_residues
PHIASKKKVLKAGKPAPCPRFHRQEQEANVSDKNQNLQDIFLNALRKSKTPVTMFLVKGVKLQGIITWFDNFSLLLRRDG
QSQLVYKHAISTVMPSHDFDLSLLGGNLRDAPASKGKALQDVFLNAVRRSDESVTMFLVNGVMLQGDIVAFDLFCMLLER
ERQVQLVYKHAISTVQPNGPINLTDNGDDEAAEDS

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=64, Percent_Identity=60.9375, Blast_Score=81, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 21891; Mature: 21760

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIASKKKVLKAGKPAPCPRFHRQEQEANVSDKNQNLQDIFLNALRKSKTPVTMFLVKG
CCCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECC
VKLQGIITWFDNFSLLLRRDGQSQLVYKHAISTVMPSHDFDLSLLGGNLRDAPASKGKAL
CEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHH
QDVFLNAVRRSDESVTMFLVNGVMLQGDIVAFDLFCMLLERERQVQLVYKHAISTVQPNG
HHHHHHHHHCCCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PINLTDNGDDEAAEDS
CEECCCCCCCCCCCCC
>Mature Secondary Structure 
PHIASKKKVLKAGKPAPCPRFHRQEQEANVSDKNQNLQDIFLNALRKSKTPVTMFLVKG
CCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECC
VKLQGIITWFDNFSLLLRRDGQSQLVYKHAISTVMPSHDFDLSLLGGNLRDAPASKGKAL
CEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHH
QDVFLNAVRRSDESVTMFLVNGVMLQGDIVAFDLFCMLLERERQVQLVYKHAISTVQPNG
HHHHHHHHHCCCCCEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PINLTDNGDDEAAEDS
CEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA