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The map label for this gene is hflX [H]

Identifier: 103486757

GI number: 103486757

Start: 1326710

End: 1328008

Strand: Reverse

Name: hflX [H]

Synonym: Sala_1271

Alternate gene names: 103486757

Gene position: 1328008-1326710 (Counterclockwise)

Preceding gene: 103486758

Following gene: 103486739

Centisome position: 39.7

GC content: 64.9

Gene sequence:

>1299_bases
ATGATTATCGTGCCCGAATGGCATGGCCAGCGCCTTGCCCGCGACCTCGATGCACGGGCGGAGGAAGCGAAGGGACTCGC
GCTTGCTATCGGGCTCGATGTGGTGGCGATCCACAGGCTCCGGCTGCGCCAGACGCGCGCGGCGACCCTGCTCGGAGTGG
GGCAAATCGAAGCGATCGTGCCCGACATCGCTGCAAGGGGCGTCCAGTTGGTCGTGGTCGATGCCTCACTCACGGCGATC
CAGCAACGGAACCTTGAAACCGCCTTCGGCACCAAGGTGATCGACCGTACCGGTCTGATCCTCGAAATCTTTGGCGAGCG
CGCCGCGACGGCCGAGGGCCGATTACAGGTCGAACTGGCCCATCTCGACTATCAGGCAGGGCGGCTCGTGCGCAGTTGGA
CGCACCTCGAACGCCAGCGCGGCGGCTTCGGTTTCCTCGGCGGTCCTGGCGAAACGCAGATCGAGGCCGATCGGCGGATG
ATCCGGAACCGGATGGCGCGCATCCGTCGCAGCCTGGAGGACGCGCGGCGCACGCGCCAGCTCCAACGGACCAAGCGGCA
GCGTGCTCCGTGGCCGGTGATCGCGCTCGTTGGCTATACCAACGCCGGAAAATCAACCTTCTTCAACCGTTTGACCGGTA
GCGACGTCATGGCGGAAGACATGCTCTTTGCAACGCTGGACCCCACGATGCGCGAAATCCGTCTGCCCGGCATCGACAAG
GCGATCCTGTCGGATACGGTCGGTTTTGTATCCGACCTGCCGACCGAACTGGTCGCGGCGTTCCGCGCGACGCTGGAGGA
GGTCACGACCGCCGACCTGATCGTCCACGTCCGCGATATCGTACATCCCGACACCGACGCGCAATATGAAGACGTGCGTG
CGATTCTCGACTCGCTGGGCGTCAATGGGCCGCAGGACGGGGAGGGCGCCGACACTGCAAGCGCGATCCCGCAGATCGAA
ATCTGGAACAAGGTCGACACGGCCAACGTCGATCGACGCGCGGCGATCGAAGACATGGCGGCGCGGCGCAGCGACGTTGC
GATCATTTCCGCCGCCACGGGCGAGGGGGTAGAAGCTGCACGGACGCTCATGGCGTCACAATTGACCGCACGCCACCAGG
TTCAGCGCATCTACCTCGGTTATGAACAGGGCGATGCAGCGGCATGGTTGCATGCGCGCGGTGAAGTGCTCGCGGACGAA
GCTGAAGGCGAGGGGCATGTGCTGACCGTTCGGCTCGATCCGGCGGATCGCGCCCGCTTTGAAAGGCTGTGGCCCGCTAA
CGGCCCTCCGTCGCCTTGA

Upstream 100 bases:

>100_bases
CCATCAACCTGACCGACAATGGCGACGACGAAGCGGCGGAAGACAGCTGATCGACCCGTTAGTCACTAGCGAAGACGAGG
TTACGCGCGGCACGGCCGCG

Downstream 100 bases:

>100_bases
CGGCTTTCCAGTGCGCCTCCTGCGCGCCGAGCGACAGTCCTGCCAGGGAACCGCCCGCCCGCGCCTCCATTGCGGCAAAG
CGCCGCGCGAACTTCAGATT

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MIIVPEWHGQRLARDLDARAEEAKGLALAIGLDVVAIHRLRLRQTRAATLLGVGQIEAIVPDIAARGVQLVVVDASLTAI
QQRNLETAFGTKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRM
IRNRMARIRRSLEDARRTRQLQRTKRQRAPWPVIALVGYTNAGKSTFFNRLTGSDVMAEDMLFATLDPTMREIRLPGIDK
AILSDTVGFVSDLPTELVAAFRATLEEVTTADLIVHVRDIVHPDTDAQYEDVRAILDSLGVNGPQDGEGADTASAIPQIE
IWNKVDTANVDRRAAIEDMAARRSDVAIISAATGEGVEAARTLMASQLTARHQVQRIYLGYEQGDAAAWLHARGEVLADE
AEGEGHVLTVRLDPADRARFERLWPANGPPSP

Sequences:

>Translated_432_residues
MIIVPEWHGQRLARDLDARAEEAKGLALAIGLDVVAIHRLRLRQTRAATLLGVGQIEAIVPDIAARGVQLVVVDASLTAI
QQRNLETAFGTKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRM
IRNRMARIRRSLEDARRTRQLQRTKRQRAPWPVIALVGYTNAGKSTFFNRLTGSDVMAEDMLFATLDPTMREIRLPGIDK
AILSDTVGFVSDLPTELVAAFRATLEEVTTADLIVHVRDIVHPDTDAQYEDVRAILDSLGVNGPQDGEGADTASAIPQIE
IWNKVDTANVDRRAAIEDMAARRSDVAIISAATGEGVEAARTLMASQLTARHQVQRIYLGYEQGDAAAWLHARGEVLADE
AEGEGHVLTVRLDPADRARFERLWPANGPPSP
>Mature_432_residues
MIIVPEWHGQRLARDLDARAEEAKGLALAIGLDVVAIHRLRLRQTRAATLLGVGQIEAIVPDIAARGVQLVVVDASLTAI
QQRNLETAFGTKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRM
IRNRMARIRRSLEDARRTRQLQRTKRQRAPWPVIALVGYTNAGKSTFFNRLTGSDVMAEDMLFATLDPTMREIRLPGIDK
AILSDTVGFVSDLPTELVAAFRATLEEVTTADLIVHVRDIVHPDTDAQYEDVRAILDSLGVNGPQDGEGADTASAIPQIE
IWNKVDTANVDRRAAIEDMAARRSDVAIISAATGEGVEAARTLMASQLTARHQVQRIYLGYEQGDAAAWLHARGEVLADE
AEGEGHVLTVRLDPADRARFERLWPANGPPSP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=304, Percent_Identity=32.8947368421053, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI310124269, Length=285, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310124267, Length=285, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310124171, Length=285, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310124169, Length=285, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310133118, Length=304, Percent_Identity=32.8947368421053, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1790615, Length=378, Percent_Identity=40.2116402116402, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17561038, Length=357, Percent_Identity=31.6526610644258, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24650079, Length=423, Percent_Identity=32.387706855792, Blast_Score=147, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47478; Mature: 47478

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVPEWHGQRLARDLDARAEEAKGLALAIGLDVVAIHRLRLRQTRAATLLGVGQIEAIV
CEECCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PDIAARGVQLVVVDASLTAIQQRNLETAFGTKVIDRTGLILEIFGERAATAEGRLQVELA
HHHHHCCEEEEEEECHHHHHHHHCCHHHHCCHHHHCCCCEEEECCCHHCCCCCEEEEEEE
HLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRMIRNRMARIRRSLEDARRTRQ
ECCHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRTKRQRAPWPVIALVGYTNAGKSTFFNRLTGSDVMAEDMLFATLDPTMREIRLPGIDK
HHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCH
AILSDTVGFVSDLPTELVAAFRATLEEVTTADLIVHVRDIVHPDTDAQYEDVRAILDSLG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
VNGPQDGEGADTASAIPQIEIWNKVDTANVDRRAAIEDMAARRSDVAIISAATGEGVEAA
CCCCCCCCCCCHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
RTLMASQLTARHQVQRIYLGYEQGDAAAWLHARGEVLADEAEGEGHVLTVRLDPADRARF
HHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCEEEECCCCCCCEEEEEECCCHHHHH
ERLWPANGPPSP
HHCCCCCCCCCC
>Mature Secondary Structure
MIIVPEWHGQRLARDLDARAEEAKGLALAIGLDVVAIHRLRLRQTRAATLLGVGQIEAIV
CEECCCCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PDIAARGVQLVVVDASLTAIQQRNLETAFGTKVIDRTGLILEIFGERAATAEGRLQVELA
HHHHHCCEEEEEEECHHHHHHHHCCHHHHCCHHHHCCCCEEEECCCHHCCCCCEEEEEEE
HLDYQAGRLVRSWTHLERQRGGFGFLGGPGETQIEADRRMIRNRMARIRRSLEDARRTRQ
ECCHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRTKRQRAPWPVIALVGYTNAGKSTFFNRLTGSDVMAEDMLFATLDPTMREIRLPGIDK
HHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHCCCCCCH
AILSDTVGFVSDLPTELVAAFRATLEEVTTADLIVHVRDIVHPDTDAQYEDVRAILDSLG
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
VNGPQDGEGADTASAIPQIEIWNKVDTANVDRRAAIEDMAARRSDVAIISAATGEGVEAA
CCCCCCCCCCCHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
RTLMASQLTARHQVQRIYLGYEQGDAAAWLHARGEVLADEAEGEGHVLTVRLDPADRARF
HHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCEEEECCCCCCCEEEEEECCCHHHHH
ERLWPANGPPSP
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]