Click here to switch to the map view.

The map label for this gene is gpo [H]

Identifier: 103486666

GI number: 103486666

Start: 1214127

End: 1214603

Strand: Direct

Name: gpo [H]

Synonym: Sala_1178

Alternate gene names: 103486666

Gene position: 1214127-1214603 (Clockwise)

Preceding gene: 103486665

Following gene: 103486667

Centisome position: 36.29

GC content: 58.7

Gene sequence:

>477_bases
ATGGGACTTTACGATCTTTCCGCAAAACTGCCGGGCGGCGGCACGCAGTCGCTCGCCGATTACCGGGGCAAGGTGCTGCT
GATCGTCAACACGGCGTCGAAATGCGGCTTCACGCCCCAATATGAGGGGCTGGAGGAGCTTTACCGCGATTATAGGGATC
GCGGCTTCGAGATACTGGCCTTTCCGTGCAACCAGTTCGGCGCGCAGGAGCCTGGCGATGCCGAGGAGATCAGGACCTTC
TGCTCGCTCACCTATGATGTCTCCTTCCCCCTGATGGCGAAAATCGACGTCAACGGCGACGATGCCGACCCGATCTTCAA
GCATTTGAAGAAGGAAAAGACCGGGTTGCTTGGCAGCGCGATAAAGTGGAACTTTACGAAGTTTCTGGTGGATCGCGACG
GCAAGGTCGTATCTCGCCACGCGCCGACGACCAGGCCCGAGCAGCTGCGGAAAGAGATTGAGGAACTGCTGGGCTGA

Upstream 100 bases:

>100_bases
GCGGTGCGTCAACATGGCGAGCAGTCGCTCGATCATGGGCTGACGTGGACGACGCGTTTCGATTTCCTCTACAGACCGCG
CATGGCGGAGGAGAAGTGAC

Downstream 100 bases:

>100_bases
GAAAAACTCGTCATTGCGCGCGAAGCGAAGCAATCTCCAGCTATCGCGGTCGAGCGAGGCCAATAGCTGGAGATTGCTTC
GTCGCCTCCGGCTCCTCGCA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MGLYDLSAKLPGGGTQSLADYRGKVLLIVNTASKCGFTPQYEGLEELYRDYRDRGFEILAFPCNQFGAQEPGDAEEIRTF
CSLTYDVSFPLMAKIDVNGDDADPIFKHLKKEKTGLLGSAIKWNFTKFLVDRDGKVVSRHAPTTRPEQLRKEIEELLG

Sequences:

>Translated_158_residues
MGLYDLSAKLPGGGTQSLADYRGKVLLIVNTASKCGFTPQYEGLEELYRDYRDRGFEILAFPCNQFGAQEPGDAEEIRTF
CSLTYDVSFPLMAKIDVNGDDADPIFKHLKKEKTGLLGSAIKWNFTKFLVDRDGKVVSRHAPTTRPEQLRKEIEELLG
>Mature_157_residues
GLYDLSAKLPGGGTQSLADYRGKVLLIVNTASKCGFTPQYEGLEELYRDYRDRGFEILAFPCNQFGAQEPGDAEEIRTFC
SLTYDVSFPLMAKIDVNGDDADPIFKHLKKEKTGLLGSAIKWNFTKFLVDRDGKVVSRHAPTTRPEQLRKEIEELLG

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=47.4358974358974, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI75709200, Length=154, Percent_Identity=46.7532467532467, Blast_Score=136, Evalue=6e-33,
Organism=Homo sapiens, GI90903240, Length=154, Percent_Identity=46.7532467532467, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI90903238, Length=129, Percent_Identity=48.8372093023256, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI192455698, Length=161, Percent_Identity=39.1304347826087, Blast_Score=113, Evalue=6e-26,
Organism=Homo sapiens, GI4557629, Length=157, Percent_Identity=36.3057324840764, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=37.1584699453552, Blast_Score=88, Evalue=3e-18,
Organism=Homo sapiens, GI33186887, Length=158, Percent_Identity=36.0759493670886, Blast_Score=83, Evalue=9e-17,
Organism=Homo sapiens, GI6006001, Length=156, Percent_Identity=35.2564102564103, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=30.939226519337, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1788003, Length=155, Percent_Identity=45.8064516129032, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17506887, Length=157, Percent_Identity=51.5923566878981, Blast_Score=163, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17535473, Length=156, Percent_Identity=48.7179487179487, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=42.6751592356688, Blast_Score=133, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI193210707, Length=160, Percent_Identity=45, Blast_Score=132, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI193209493, Length=181, Percent_Identity=33.7016574585635, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=33.1491712707182, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17507603, Length=106, Percent_Identity=39.622641509434, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=39.3617021276596, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=39.4736842105263, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=156, Percent_Identity=58.3333333333333, Blast_Score=193, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6322228, Length=137, Percent_Identity=62.043795620438, Blast_Score=184, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=49.0445859872611, Blast_Score=148, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24656767, Length=159, Percent_Identity=49.685534591195, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=49.6894409937888, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24656777, Length=159, Percent_Identity=49.685534591195, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=42.5, Blast_Score=115, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17711; Mature: 17580

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLYDLSAKLPGGGTQSLADYRGKVLLIVNTASKCGFTPQYEGLEELYRDYRDRGFEILA
CCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEEE
FPCNQFGAQEPGDAEEIRTFCSLTYDVSFPLMAKIDVNGDDADPIFKHLKKEKTGLLGSA
ECCHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCH
IKWNFTKFLVDRDGKVVSRHAPTTRPEQLRKEIEELLG
HHHHHEEEEECCCCCEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
GLYDLSAKLPGGGTQSLADYRGKVLLIVNTASKCGFTPQYEGLEELYRDYRDRGFEILA
CCCCCCCCCCCCCCCHHHHHCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCEEEE
FPCNQFGAQEPGDAEEIRTFCSLTYDVSFPLMAKIDVNGDDADPIFKHLKKEKTGLLGSA
ECCHHCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCH
IKWNFTKFLVDRDGKVVSRHAPTTRPEQLRKEIEELLG
HHHHHEEEEECCCCCEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]