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The map label for this gene is moaE [H]

Identifier: 103486644

GI number: 103486644

Start: 1190299

End: 1190739

Strand: Direct

Name: moaE [H]

Synonym: Sala_1156

Alternate gene names: 103486644

Gene position: 1190299-1190739 (Clockwise)

Preceding gene: 103486643

Following gene: 103486646

Centisome position: 35.58

GC content: 66.21

Gene sequence:

>441_bases
ATGATCCGCGTGTTCGTCCAGACTGTGCCGATCGCGGTCGGCGCAGAGTTCGATCTGCACGATGCGGGCGGGCACGGCGC
GAGCGCAAGCTTTATCGGGCGTGTGCGCAGCGACGACGGATTGACCGAATTGTTCCTCGAACATCATCCGACGATGACCG
AGGCGGAACTCGCCAGCCTCGCCCATGCGGCGGTCGATCGTTGGAAACTGGGCGCGCTGACGCTGATCCACCGTGTCGGT
GCGATGGCGCCGGGCGAAACCATCGTGCTCGTCCTTGCGAGCAGCCGTCACCGCGCCGAAGCGCTGGCGGCATGCGAGTT
TCTGATCGACCGGCTGAAGACCGACGTGATGCTGTGGAAGCGCGAGACCTTTGCCGACGGGCGCGTGGCGTGGGTCGAGG
AACGCGAGGGCGATCGTGCGCGGGCGGAGCGGTGGGATTAG

Upstream 100 bases:

>100_bases
CGCACCGCATTCGCGCTGCGATCGACGGCGCGATGATGGGCCCCGACGCGCCGCTTGCGGGCGCGCGCGAGGTCGCGCTG
TTCCCGCCGGTGACCGGCGG

Downstream 100 bases:

>100_bases
CGTCGTGGGCCCTGAAACAGGTCCGGAGTGACGAAGATTGTGCCGCTAGCACGCCGCTCTATCCCGCCTGATGCTTCCTG
AAAATATCGGCGAGCATGCG

Product: molybdopterin biosynthesis MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MIRVFVQTVPIAVGAEFDLHDAGGHGASASFIGRVRSDDGLTELFLEHHPTMTEAELASLAHAAVDRWKLGALTLIHRVG
AMAPGETIVLVLASSRHRAEALAACEFLIDRLKTDVMLWKRETFADGRVAWVEEREGDRARAERWD

Sequences:

>Translated_146_residues
MIRVFVQTVPIAVGAEFDLHDAGGHGASASFIGRVRSDDGLTELFLEHHPTMTEAELASLAHAAVDRWKLGALTLIHRVG
AMAPGETIVLVLASSRHRAEALAACEFLIDRLKTDVMLWKRETFADGRVAWVEEREGDRARAERWD
>Mature_146_residues
MIRVFVQTVPIAVGAEFDLHDAGGHGASASFIGRVRSDDGLTELFLEHHPTMTEAELASLAHAAVDRWKLGALTLIHRVG
AMAPGETIVLVLASSRHRAEALAACEFLIDRLKTDVMLWKRETFADGRVAWVEEREGDRARAERWD

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Escherichia coli, GI1787003, Length=147, Percent_Identity=42.1768707482993, Blast_Score=113, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21356259, Length=140, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16143; Mature: 16143

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVFVQTVPIAVGAEFDLHDAGGHGASASFIGRVRSDDGLTELFLEHHPTMTEAELASL
CEEEEEEECCEEECCCCCCCCCCCCCCCHHHHEECCCCCCHHHHHHHCCCCCCHHHHHHH
AHAAVDRWKLGALTLIHRVGAMAPGETIVLVLASSRHRAEALAACEFLIDRLKTDVMLWK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RETFADGRVAWVEEREGDRARAERWD
HCCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MIRVFVQTVPIAVGAEFDLHDAGGHGASASFIGRVRSDDGLTELFLEHHPTMTEAELASL
CEEEEEEECCEEECCCCCCCCCCCCCCCHHHHEECCCCCCHHHHHHHCCCCCCHHHHHHH
AHAAVDRWKLGALTLIHRVGAMAPGETIVLVLASSRHRAEALAACEFLIDRLKTDVMLWK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RETFADGRVAWVEEREGDRARAERWD
HCCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]