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The map label for this gene is ispH [H]

Identifier: 103486624

GI number: 103486624

Start: 1173516

End: 1174496

Strand: Reverse

Name: ispH [H]

Synonym: Sala_1136

Alternate gene names: 103486624

Gene position: 1174496-1173516 (Counterclockwise)

Preceding gene: 103486634

Following gene: 103486623

Centisome position: 35.11

GC content: 66.26

Gene sequence:

>981_bases
ATGAACGCACATCATCCGACGATGTCGGCGACGACCCGCGACGGCGCCCTGCTCAAGGTGCTGATCGCGGCACCGCGCGG
TTTTTGCGCGGGCGTCGACCGCGCGATCCGCATCGTCGAACTGGCGCTCGAACGGTTCGGTGCGCCGGTCTATGTCCGGC
ACGAGATCGTCCACAACCGTTATGTCGTCGAATCGCTGAAGGCGAAGGGCGCGATCTTCGTCGAATCGCTTGATCAGGTG
CCCGACGGCGTTCCCGTGGTTTTCAGCGCCCACGGCGTGCCGAAAGCGGTGCCCGCGAAGGCCGAAATGCGGGGGCTCGA
CTATATCGACGCGACCTGTCCCCTGGTCTCGAAAGTGCATCGGCAGGCCGAGCGCGCGCATGAAGCCGGTCGCCACATCA
TTTTCATCGGCCATGCCGGTCACCCGGAGGTTGTCGGGACGCTCGGGCAATTGCCCGATGGCGCAATGACGCTGGTCGAA
TCGGTCGACGATGTCGCCGCGCTGGCACCGGTCGATGAAGACAGGCTTTCATTTCTGACGCAGACGACGCTCTCGGTCGA
CGACACGCGCGACATCGTCGCCGCGCTGCGCCATCGCTTCCCGGCCATCGCCGGGCCGCGCGGCGAGGATATTTGCTATG
CGACCTCAAACCGGCAGGAAGCGGTCAAGGCCATTGCGGCACGCTGCGACCGGATGATCGTGATCGGCGCGCCGAACAGT
TCGAACAGCCTCCGGCTCGTCGAGGTGGCCGAGCGGCTCGGCACCCCGGCGCATCTCGTCCAGCGCGGCCACGACGTCGA
CCCGGCGTGGCTTGATTCCATCGGTACGCTCGGCATCACTGCGGGGGCCAGCGCGCCCGAAACGCTGGTGCGCGAGGTCA
TCGACGCGGTTTCCGCGGTGCGCCCGATCGTCGAGGACGTCGTCGTGACCGCCGAGGAGAATATGGTGTTCAAACTGCCG
CGCGGCCTCGAAGCTGCCTGA

Upstream 100 bases:

>100_bases
CCCGCTTCATGCGCGCCGCTTCTTATCGGTGCGATGAACAAGGCGCAACCGACGAAGCGGCTTTACCCCGCCGCACCTGC
TGCGCTAGAGCGCGCGCACC

Downstream 100 bases:

>100_bases
TGGCCGTCTATACCCACGTCGAACCCGACGACCTTGCCGCGCTGGTCGCCCAATATGACATCGGGACGGTCGTATCGTGC
AAGGGGATTGCCGAGGGAGT

Product: hydroxymethylbutenyl pyrophosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNAHHPTMSATTRDGALLKVLIAAPRGFCAGVDRAIRIVELALERFGAPVYVRHEIVHNRYVVESLKAKGAIFVESLDQV
PDGVPVVFSAHGVPKAVPAKAEMRGLDYIDATCPLVSKVHRQAERAHEAGRHIIFIGHAGHPEVVGTLGQLPDGAMTLVE
SVDDVAALAPVDEDRLSFLTQTTLSVDDTRDIVAALRHRFPAIAGPRGEDICYATSNRQEAVKAIAARCDRMIVIGAPNS
SNSLRLVEVAERLGTPAHLVQRGHDVDPAWLDSIGTLGITAGASAPETLVREVIDAVSAVRPIVEDVVVTAEENMVFKLP
RGLEAA

Sequences:

>Translated_326_residues
MNAHHPTMSATTRDGALLKVLIAAPRGFCAGVDRAIRIVELALERFGAPVYVRHEIVHNRYVVESLKAKGAIFVESLDQV
PDGVPVVFSAHGVPKAVPAKAEMRGLDYIDATCPLVSKVHRQAERAHEAGRHIIFIGHAGHPEVVGTLGQLPDGAMTLVE
SVDDVAALAPVDEDRLSFLTQTTLSVDDTRDIVAALRHRFPAIAGPRGEDICYATSNRQEAVKAIAARCDRMIVIGAPNS
SNSLRLVEVAERLGTPAHLVQRGHDVDPAWLDSIGTLGITAGASAPETLVREVIDAVSAVRPIVEDVVVTAEENMVFKLP
RGLEAA
>Mature_326_residues
MNAHHPTMSATTRDGALLKVLIAAPRGFCAGVDRAIRIVELALERFGAPVYVRHEIVHNRYVVESLKAKGAIFVESLDQV
PDGVPVVFSAHGVPKAVPAKAEMRGLDYIDATCPLVSKVHRQAERAHEAGRHIIFIGHAGHPEVVGTLGQLPDGAMTLVE
SVDDVAALAPVDEDRLSFLTQTTLSVDDTRDIVAALRHRFPAIAGPRGEDICYATSNRQEAVKAIAARCDRMIVIGAPNS
SNSLRLVEVAERLGTPAHLVQRGHDVDPAWLDSIGTLGITAGASAPETLVREVIDAVSAVRPIVEDVVVTAEENMVFKLP
RGLEAA

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=308, Percent_Identity=54.5454545454545, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 34866; Mature: 34866

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHHPTMSATTRDGALLKVLIAAPRGFCAGVDRAIRIVELALERFGAPVYVRHEIVHNR
CCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
YVVESLKAKGAIFVESLDQVPDGVPVVFSAHGVPKAVPAKAEMRGLDYIDATCPLVSKVH
HHHHHHHCCCCCEEHHHHHCCCCCCEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
RQAERAHEAGRHIIFIGHAGHPEVVGTLGQLPDGAMTLVESVDDVAALAPVDEDRLSFLT
HHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
QTTLSVDDTRDIVAALRHRFPAIAGPRGEDICYATSNRQEAVKAIAARCDRMIVIGAPNS
HHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEECCCC
SNSLRLVEVAERLGTPAHLVQRGHDVDPAWLDSIGTLGITAGASAPETLVREVIDAVSAV
CCCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHH
RPIVEDVVVTAEENMVFKLPRGLEAA
HHHHHHHHEECCCCEEEECCCCCCCC
>Mature Secondary Structure
MNAHHPTMSATTRDGALLKVLIAAPRGFCAGVDRAIRIVELALERFGAPVYVRHEIVHNR
CCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
YVVESLKAKGAIFVESLDQVPDGVPVVFSAHGVPKAVPAKAEMRGLDYIDATCPLVSKVH
HHHHHHHCCCCCEEHHHHHCCCCCCEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHH
RQAERAHEAGRHIIFIGHAGHPEVVGTLGQLPDGAMTLVESVDDVAALAPVDEDRLSFLT
HHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
QTTLSVDDTRDIVAALRHRFPAIAGPRGEDICYATSNRQEAVKAIAARCDRMIVIGAPNS
HHHCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEECCCC
SNSLRLVEVAERLGTPAHLVQRGHDVDPAWLDSIGTLGITAGASAPETLVREVIDAVSAV
CCCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHH
RPIVEDVVVTAEENMVFKLPRGLEAA
HHHHHHHHEECCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA