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The map label for this gene is thrB [H]

Identifier: 103486623

GI number: 103486623

Start: 1172554

End: 1173516

Strand: Reverse

Name: thrB [H]

Synonym: Sala_1135

Alternate gene names: 103486623

Gene position: 1173516-1172554 (Counterclockwise)

Preceding gene: 103486624

Following gene: 103486622

Centisome position: 35.08

GC content: 65.21

Gene sequence:

>963_bases
ATGGCCGTCTATACCCACGTCGAACCCGACGACCTTGCCGCGCTGGTCGCCCAATATGACATCGGGACGGTCGTATCGTG
CAAGGGGATTGCCGAGGGAGTCGAGAACAGCAATTTCCTGCTCGAAACAACGCGCGGGCGCTTCATTCTGACGCTTTACG
AAAAGCGCGTCAGCGAAGGTGATCTGCCCTTTTTCGTCGAGCTGCTCGACCATCTAGCGAAACGCGGCTGCCCCGTTCCG
GCCATGATCCGCGACCGTGAAGGCCGGGCAATCCAGCAGGTTTCGGAACGCGCGGCGTGCATCATCCAGTTCCTGCCCGG
CATTTCGCTGACCCATCCCACGCCCGGACAGTGTCAGGCGGCCGGCGCCGCAATGGGCGCGATGCACCGCGCGGTCGCCG
ATTTCGCGGGCGCGCGCGAAAACAGCATGGGGCATCGCCACTGGCGCGCGATTGCCCAGGGCGCGGGCGATCTCGACGCG
GTGATTCCGGGATTGCAGGCCATCGTCGACGAGGAACTCGACCATCTCGACGCCCACTGGCCGCGCGACCTGCCCGCGCA
TGTCGTCCACGCTGATCTGTTCCCCGACAATGTGCTGATGCTTGGCGAGCGCGTCACCGGCCTGATCGATTTCTATTTCG
CAGCAAGCGATTTTCGCGCTTACGATGTAGCGGTAACGCACGCTTCGTGGACCTTCTCCACCGATGGCAGCGACTGCGAT
ATCGGGCGCGCCAGCGCGCTGATGCGCGGCTATGCCCGCGAAGTCGCACTGACCGACGAAGAGTTTGCGGCGCTGCCGCT
GCTGGCGCGCGGCGCGGCGCTGCGCTTTTTGCTGACGCGGGCGCACGACTGGATTCATACGCCACCGGGCGCGCTCGTCA
CCCGCAAGGATCCGGCGCCCTTTCTTGCACGGCTGCGGCGTTATCAGGCGGCCGACGCGGCCGCGCTCTTCTCCGCAGCA
TGA

Upstream 100 bases:

>100_bases
TCGACGCGGTTTCCGCGGTGCGCCCGATCGTCGAGGACGTCGTCGTGACCGCCGAGGAGAATATGGTGTTCAAACTGCCG
CGCGGCCTCGAAGCTGCCTG

Downstream 100 bases:

>100_bases
GCGAGCGGCGTACGGTCATCGTCGCCACCGACGGGGCGTGCAAGGGCAATCCAGGCCCCGGCGGCTGGGGTGCCGTCCTG
CGCTGGGGCGAGGTGGTCAA

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAVYTHVEPDDLAALVAQYDIGTVVSCKGIAEGVENSNFLLETTRGRFILTLYEKRVSEGDLPFFVELLDHLAKRGCPVP
AMIRDREGRAIQQVSERAACIIQFLPGISLTHPTPGQCQAAGAAMGAMHRAVADFAGARENSMGHRHWRAIAQGAGDLDA
VIPGLQAIVDEELDHLDAHWPRDLPAHVVHADLFPDNVLMLGERVTGLIDFYFAASDFRAYDVAVTHASWTFSTDGSDCD
IGRASALMRGYAREVALTDEEFAALPLLARGAALRFLLTRAHDWIHTPPGALVTRKDPAPFLARLRRYQAADAAALFSAA

Sequences:

>Translated_320_residues
MAVYTHVEPDDLAALVAQYDIGTVVSCKGIAEGVENSNFLLETTRGRFILTLYEKRVSEGDLPFFVELLDHLAKRGCPVP
AMIRDREGRAIQQVSERAACIIQFLPGISLTHPTPGQCQAAGAAMGAMHRAVADFAGARENSMGHRHWRAIAQGAGDLDA
VIPGLQAIVDEELDHLDAHWPRDLPAHVVHADLFPDNVLMLGERVTGLIDFYFAASDFRAYDVAVTHASWTFSTDGSDCD
IGRASALMRGYAREVALTDEEFAALPLLARGAALRFLLTRAHDWIHTPPGALVTRKDPAPFLARLRRYQAADAAALFSAA
>Mature_319_residues
AVYTHVEPDDLAALVAQYDIGTVVSCKGIAEGVENSNFLLETTRGRFILTLYEKRVSEGDLPFFVELLDHLAKRGCPVPA
MIRDREGRAIQQVSERAACIIQFLPGISLTHPTPGQCQAAGAAMGAMHRAVADFAGARENSMGHRHWRAIAQGAGDLDAV
IPGLQAIVDEELDHLDAHWPRDLPAHVVHADLFPDNVLMLGERVTGLIDFYFAASDFRAYDVAVTHASWTFSTDGSDCDI
GRASALMRGYAREVALTDEEFAALPLLARGAALRFLLTRAHDWIHTPPGALVTRKDPAPFLARLRRYQAADAAALFSAA

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 34824; Mature: 34693

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVYTHVEPDDLAALVAQYDIGTVVSCKGIAEGVENSNFLLETTRGRFILTLYEKRVSEG
CEEEECCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCEEEEECCCCEEEEEEHHHCCCC
DLPFFVELLDHLAKRGCPVPAMIRDREGRAIQQVSERAACIIQFLPGISLTHPTPGQCQA
CCHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AGAAMGAMHRAVADFAGARENSMGHRHWRAIAQGAGDLDAVIPGLQAIVDEELDHLDAHW
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PRDLPAHVVHADLFPDNVLMLGERVTGLIDFYFAASDFRAYDVAVTHASWTFSTDGSDCD
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCC
IGRASALMRGYAREVALTDEEFAALPLLARGAALRFLLTRAHDWIHTPPGALVTRKDPAP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCH
FLARLRRYQAADAAALFSAA
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVYTHVEPDDLAALVAQYDIGTVVSCKGIAEGVENSNFLLETTRGRFILTLYEKRVSEG
EEEECCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCEEEEECCCCEEEEEEHHHCCCC
DLPFFVELLDHLAKRGCPVPAMIRDREGRAIQQVSERAACIIQFLPGISLTHPTPGQCQA
CCHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
AGAAMGAMHRAVADFAGARENSMGHRHWRAIAQGAGDLDAVIPGLQAIVDEELDHLDAHW
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
PRDLPAHVVHADLFPDNVLMLGERVTGLIDFYFAASDFRAYDVAVTHASWTFSTDGSDCD
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCC
IGRASALMRGYAREVALTDEEFAALPLLARGAALRFLLTRAHDWIHTPPGALVTRKDPAP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCH
FLARLRRYQAADAAALFSAA
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA