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The map label for this gene is trpB [H]

Identifier: 103486553

GI number: 103486553

Start: 1097097

End: 1098329

Strand: Reverse

Name: trpB [H]

Synonym: Sala_1064

Alternate gene names: 103486553

Gene position: 1098329-1097097 (Counterclockwise)

Preceding gene: 103486554

Following gene: 103486552

Centisome position: 32.83

GC content: 65.04

Gene sequence:

>1233_bases
ATGGATATGACGATGACCGACGCCCCGACCCTGCCCAACAGCCTTCGCTCCGGTCCTGATGATCGCGGCCATTTCGGCCG
GTTCGGCGGCCGCTATGTCGCCGAAACGCTGATGCCGCTGATCCTCGACCTCGAACGCCATTATCGCGCCGCACAGGCCG
ACCCGGCGTTCAAGGCCGAGTTCGATTATCTGCTGAAACATTATGTCGGTCGCCCCAGCCCGCTGTGGCTGGCGCAGCGG
CTGACCGACGACCTCGGCGGCGCGAAAATCTACCTCAAGCGCGAGGATCTGAACCACACCGGCGCGCACAAGATCAACAA
TTGCATCGGCCAGATCCTGCTCGCCAAGCGCATGGGCAAGACCAAGATCATCGCCGAAACCGGCGCGGGCCAGCACGGCG
TTGCGACCGCGACCGTCGCCGCGCTCTTCGGCCTGCCCTGCACCATCTTCATGGGCGCGGTCGATGTCGCGCGGCAACAG
CCCAATGTGTTCCGCATGAAGCTGCTCGGCGCCGAAGTCGTCGCTGTGACAAGCGGCGCCAGGACGCTGAAGGATGCGAT
GAACGAGGCGCTGCGCCACTGGGTCGGACATGTACACGATACTTTCTACATCATCGGCACCGTCGCCGGGCCGCACCCCT
ATCCGCAGCTCGTCCGCGATTTCCAGTCGGTGATCGGCGACGAAGCGCGCGAACAGATACTGGAGGCGGAGGGCCGCCTC
CCCGACATGCTGATCGCCCCGGTCGGCGGCGGATCGAACGCGATCGGGCTGTTCCACCCCTTCCTCGATGACACGGACGT
CGAAATCGTCGGTGTCGAAGCCGCGGGCGAAGGGCTGGACGGCAAGCACGCCGCGAGCCTCGCGGGCGGAAAACCCGGCA
TCCTTCACGGCAACAAGACCTATCTGTTGCAGGACGCGGACGGCCAGATCACCGAAGCGCACAGCATCTCGGCAGGCCTC
GACTATCCGGGCATCGGCCCCGAACATAGCTGGCTCCACGACATCGGCCGCGTCCGCTACGAGCCCGTCACCGACGCCGA
GGCGCTGGCAAGCTTCCAGAAGCTCACCAGGCTCGAAGGCATTATCCCGGCGCTGGAGTCCGCCCACGCGATTGCTGCGG
CAGAGCGCATCGCGCCGACGCTGGGCAAGGACAAGATCATCATCGTCAATTGCTCGGGGCGGGGGGACAAGGATATTGCA
ACGGTCGCGGATGCGTTGGGGGTGAAGCTGTGA

Upstream 100 bases:

>100_bases
CGGCAGATGACCACGCTGCGACCCCTCGTCCTGCGCATCGGGAAACGATGGCGCTGATCGCTTGAGACCTGCTCTTCAAG
TGAATGCCCACCCGTAACCG

Downstream 100 bases:

>100_bases
GCGCCCATGCAAACCCTTCTCCCTTGAAGGGAGAAGGATACGAAGCCTTGGCGGCGCAGCCGCCTAGGCGCAGTTGGATG
AGGGTGAGCGAGCCTCTGGC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDMTMTDAPTLPNSLRSGPDDRGHFGRFGGRYVAETLMPLILDLERHYRAAQADPAFKAEFDYLLKHYVGRPSPLWLAQR
LTDDLGGAKIYLKREDLNHTGAHKINNCIGQILLAKRMGKTKIIAETGAGQHGVATATVAALFGLPCTIFMGAVDVARQQ
PNVFRMKLLGAEVVAVTSGARTLKDAMNEALRHWVGHVHDTFYIIGTVAGPHPYPQLVRDFQSVIGDEAREQILEAEGRL
PDMLIAPVGGGSNAIGLFHPFLDDTDVEIVGVEAAGEGLDGKHAASLAGGKPGILHGNKTYLLQDADGQITEAHSISAGL
DYPGIGPEHSWLHDIGRVRYEPVTDAEALASFQKLTRLEGIIPALESAHAIAAAERIAPTLGKDKIIIVNCSGRGDKDIA
TVADALGVKL

Sequences:

>Translated_410_residues
MDMTMTDAPTLPNSLRSGPDDRGHFGRFGGRYVAETLMPLILDLERHYRAAQADPAFKAEFDYLLKHYVGRPSPLWLAQR
LTDDLGGAKIYLKREDLNHTGAHKINNCIGQILLAKRMGKTKIIAETGAGQHGVATATVAALFGLPCTIFMGAVDVARQQ
PNVFRMKLLGAEVVAVTSGARTLKDAMNEALRHWVGHVHDTFYIIGTVAGPHPYPQLVRDFQSVIGDEAREQILEAEGRL
PDMLIAPVGGGSNAIGLFHPFLDDTDVEIVGVEAAGEGLDGKHAASLAGGKPGILHGNKTYLLQDADGQITEAHSISAGL
DYPGIGPEHSWLHDIGRVRYEPVTDAEALASFQKLTRLEGIIPALESAHAIAAAERIAPTLGKDKIIIVNCSGRGDKDIA
TVADALGVKL
>Mature_410_residues
MDMTMTDAPTLPNSLRSGPDDRGHFGRFGGRYVAETLMPLILDLERHYRAAQADPAFKAEFDYLLKHYVGRPSPLWLAQR
LTDDLGGAKIYLKREDLNHTGAHKINNCIGQILLAKRMGKTKIIAETGAGQHGVATATVAALFGLPCTIFMGAVDVARQQ
PNVFRMKLLGAEVVAVTSGARTLKDAMNEALRHWVGHVHDTFYIIGTVAGPHPYPQLVRDFQSVIGDEAREQILEAEGRL
PDMLIAPVGGGSNAIGLFHPFLDDTDVEIVGVEAAGEGLDGKHAASLAGGKPGILHGNKTYLLQDADGQITEAHSISAGL
DYPGIGPEHSWLHDIGRVRYEPVTDAEALASFQKLTRLEGIIPALESAHAIAAAERIAPTLGKDKIIIVNCSGRGDKDIA
TVADALGVKL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=388, Percent_Identity=56.1855670103093, Blast_Score=435, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=56.7708333333333, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43971; Mature: 43971

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMTMTDAPTLPNSLRSGPDDRGHFGRFGGRYVAETLMPLILDLERHYRAAQADPAFKAE
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FDYLLKHYVGRPSPLWLAQRLTDDLGGAKIYLKREDLNHTGAHKINNCIGQILLAKRMGK
HHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
TKIIAETGAGQHGVATATVAALFGLPCTIFMGAVDVARQQPNVFRMKLLGAEVVAVTSGA
EEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCH
RTLKDAMNEALRHWVGHVHDTFYIIGTVAGPHPYPQLVRDFQSVIGDEAREQILEAEGRL
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCC
PDMLIAPVGGGSNAIGLFHPFLDDTDVEIVGVEAAGEGLDGKHAASLAGGKPGILHGNKT
CCEEEEECCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCCEEECCEE
YLLQDADGQITEAHSISAGLDYPGIGPEHSWLHDIGRVRYEPVTDAEALASFQKLTRLEG
EEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IIPALESAHAIAAAERIAPTLGKDKIIIVNCSGRGDKDIATVADALGVKL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MDMTMTDAPTLPNSLRSGPDDRGHFGRFGGRYVAETLMPLILDLERHYRAAQADPAFKAE
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
FDYLLKHYVGRPSPLWLAQRLTDDLGGAKIYLKREDLNHTGAHKINNCIGQILLAKRMGK
HHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
TKIIAETGAGQHGVATATVAALFGLPCTIFMGAVDVARQQPNVFRMKLLGAEVVAVTSGA
EEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCH
RTLKDAMNEALRHWVGHVHDTFYIIGTVAGPHPYPQLVRDFQSVIGDEAREQILEAEGRL
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHCCCC
PDMLIAPVGGGSNAIGLFHPFLDDTDVEIVGVEAAGEGLDGKHAASLAGGKPGILHGNKT
CCEEEEECCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHCCCCCCEEECCEE
YLLQDADGQITEAHSISAGLDYPGIGPEHSWLHDIGRVRYEPVTDAEALASFQKLTRLEG
EEEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
IIPALESAHAIAAAERIAPTLGKDKIIIVNCSGRGDKDIATVADALGVKL
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA