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The map label for this gene is trpA [H]

Identifier: 103486552

GI number: 103486552

Start: 1096103

End: 1096897

Strand: Reverse

Name: trpA [H]

Synonym: Sala_1063

Alternate gene names: 103486552

Gene position: 1096897-1096103 (Counterclockwise)

Preceding gene: 103486553

Following gene: 103486551

Centisome position: 32.79

GC content: 70.69

Gene sequence:

>795_bases
ATGAGCACCCGCTTCGCCGCCGCCTTCGCCAAACCCCATCCCGCGCTCGTCGCCTTCATAACCGGCGGCGACGGCGACAC
CGCCGCGAACCTCGACGCGCTCGTCGCGGGGGGTGCCGATGTGATCGAGCTCGGCATGCCCTTCACCGATCCGATGGCCG
ATGGCCCCGCGATCCAGGCCGCCAACCTGCGCAGCCTCGCCAGGGGCACGACCACCGCGGACATCTTCGCCATCGCCGCC
GCCTTCCGCCAGCGCCACCCCGACACCCCGCTCGTCCTGATGGGCTATGCCAATCCGATGACGATCCGCGGGGGCGACTG
GTTCGCGGCCGAATGCGCCAGGGTCGGCGTCGATGGCGTCATCTGCGTCGATGTTCCCGCCGAGGAAGACCCCGAACTCG
GCCCCGCGCTCCGCGCCATGGGCATCGACCTCATCCGCCTTGCCACGCCCACGACCGACACCGCGCGCCTGCCCACCGTC
CTCGATGGCGCGGGCGGCTTCCTCTATTATGTCTCGGTCGCCGGCATCACCGGCCAGCAACAGGCCGCACAGGCGAGCAT
TGACGAGGCCGTCGCGCGGCTCAAGGCCGCGACCGACCTGCCCGTCGCCGTCGGCTTCGGCGTCCGCACGCCCGATCAGG
CGGCGCAGATCGCGCGCGTCGCCGACGGCGTCGTCGTCGGATCGGCCTTCATCGACATCATTGCCGCGCATGGCGACGCC
GCGGCCCCGCATGTCGAGGCTTTCACCCGCACCCTCGCCGATGCTATTCATAGCGCCAAGGAGATCGCCGCATGA

Upstream 100 bases:

>100_bases
CTCGCGCGATTGCGCAGCGATCGCATACCCCTCACCCAGCTACGACTAGCGAGCAAGCTCGCAAGTCTTCGCAACCCTCT
CCCCCAAGGGGAGAGGGGAA

Downstream 100 bases:

>100_bases
GCTGGCTCGACCGCGTTCGCAACGCCCTGCCCTTCACCGCCAAGCGCGATACCGCCGACAATCTGTGGCACAAATGCCGC
CAGTGCCAGCAGATGGTGTT

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSTRFAAAFAKPHPALVAFITGGDGDTAANLDALVAGGADVIELGMPFTDPMADGPAIQAANLRSLARGTTTADIFAIAA
AFRQRHPDTPLVLMGYANPMTIRGGDWFAAECARVGVDGVICVDVPAEEDPELGPALRAMGIDLIRLATPTTDTARLPTV
LDGAGGFLYYVSVAGITGQQQAAQASIDEAVARLKAATDLPVAVGFGVRTPDQAAQIARVADGVVVGSAFIDIIAAHGDA
AAPHVEAFTRTLADAIHSAKEIAA

Sequences:

>Translated_264_residues
MSTRFAAAFAKPHPALVAFITGGDGDTAANLDALVAGGADVIELGMPFTDPMADGPAIQAANLRSLARGTTTADIFAIAA
AFRQRHPDTPLVLMGYANPMTIRGGDWFAAECARVGVDGVICVDVPAEEDPELGPALRAMGIDLIRLATPTTDTARLPTV
LDGAGGFLYYVSVAGITGQQQAAQASIDEAVARLKAATDLPVAVGFGVRTPDQAAQIARVADGVVVGSAFIDIIAAHGDA
AAPHVEAFTRTLADAIHSAKEIAA
>Mature_263_residues
STRFAAAFAKPHPALVAFITGGDGDTAANLDALVAGGADVIELGMPFTDPMADGPAIQAANLRSLARGTTTADIFAIAAA
FRQRHPDTPLVLMGYANPMTIRGGDWFAAECARVGVDGVICVDVPAEEDPELGPALRAMGIDLIRLATPTTDTARLPTVL
DGAGGFLYYVSVAGITGQQQAAQASIDEAVARLKAATDLPVAVGFGVRTPDQAAQIARVADGVVVGSAFIDIIAAHGDAA
APHVEAFTRTLADAIHSAKEIAA

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=240, Percent_Identity=37.5, Blast_Score=152, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321412, Length=240, Percent_Identity=39.5833333333333, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 26942; Mature: 26811

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRFAAAFAKPHPALVAFITGGDGDTAANLDALVAGGADVIELGMPFTDPMADGPAIQA
CCCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHEEECCCCEEEECCCCCCCCCCCCCEEH
ANLRSLARGTTTADIFAIAAAFRQRHPDTPLVLMGYANPMTIRGGDWFAAECARVGVDGV
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCHHHHHHHCCCCEE
ICVDVPAEEDPELGPALRAMGIDLIRLATPTTDTARLPTVLDGAGGFLYYVSVAGITGQQ
EEEECCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCCHH
QAAQASIDEAVARLKAATDLPVAVGFGVRTPDQAAQIARVADGVVVGSAFIDIIAAHGDA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCEEEHHHHHHHHHCCCCC
AAPHVEAFTRTLADAIHSAKEIAA
CCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STRFAAAFAKPHPALVAFITGGDGDTAANLDALVAGGADVIELGMPFTDPMADGPAIQA
CCCHHHHHCCCCCEEEEEEECCCCCCCCCCHHEEECCCCEEEECCCCCCCCCCCCCEEH
ANLRSLARGTTTADIFAIAAAFRQRHPDTPLVLMGYANPMTIRGGDWFAAECARVGVDGV
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCHHHHHHHCCCCEE
ICVDVPAEEDPELGPALRAMGIDLIRLATPTTDTARLPTVLDGAGGFLYYVSVAGITGQQ
EEEECCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCCEEEECCCCEEEEEEECCCCCHH
QAAQASIDEAVARLKAATDLPVAVGFGVRTPDQAAQIARVADGVVVGSAFIDIIAAHGDA
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCEEEHHHHHHHHHCCCCC
AAPHVEAFTRTLADAIHSAKEIAA
CCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA