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The map label for this gene is iorA [H]

Identifier: 103486526

GI number: 103486526

Start: 1071275

End: 1071814

Strand: Reverse

Name: iorA [H]

Synonym: Sala_1037

Alternate gene names: 103486526

Gene position: 1071814-1071275 (Counterclockwise)

Preceding gene: 103486527

Following gene: 103486525

Centisome position: 32.04

GC content: 67.41

Gene sequence:

>540_bases
ATGACGCGATTCTCGGTCAACGACCGTCCGGTCGAATATCGCATGGAGCCCGAAACCCCGCTGCTTTGGGCGCTGCGCGA
TGCGTCGAACCTTACCGGCACCAAATATGGCTGTGGCACCGGCGATTGCGGTGCCTGCACCGTCGACATCGACGGCGAGG
CGATCCGCAGCTGCCTGGTCACCATCGCCGAATGCGAAGGCCGCTTCGTCACGACGATCGAGGGCCTGACGCGCGACCGT
AGCCACCCCGTTCAACAGGCGTGGGTCGCCGAACAGGTGCCGCAATGCGGTTTCTGCCAGTCAGGGATGATCATGGCCGC
CGCCGTGCTGCTCCGCAAGAACAGCAACCCAAGCGATGCCGAAGTCGATGCCGCGATGACCAATATCTGCCGCTGTGGCA
CCTATCCGCGCATTCGCGCCGCGATCCGCCTCGCAGCGCGGGTCATGCGCGGCGAGGAACGCATCGCCGCCGCGCCGCCG
CCCGGCATCCGGCCCGAAGACGCCGCGCGCGCGGTACCGGCGCTGCGCCCCGAAAGCTGA

Upstream 100 bases:

>100_bases
CCAGTCGGGCAAGGCCGAGTTCGACGCGATGGTACGCAAGGTCGACAAGATCGACACAAGTTGGCGTGACTAATCCGCTC
GCTGCGCTAACAGGGGCGGC

Downstream 100 bases:

>100_bases
ACCGCGGGCAACGGCGCGGTCAGCCATCGATCATCTTGCCTCGGGTAAGAATCGATTCATCATCCCGGCTGGCGTCTCCA
GCGATCGGGACGTGAGTTGG

Product: (2Fe-2S)-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTRFSVNDRPVEYRMEPETPLLWALRDASNLTGTKYGCGTGDCGACTVDIDGEAIRSCLVTIAECEGRFVTTIEGLTRDR
SHPVQQAWVAEQVPQCGFCQSGMIMAAAVLLRKNSNPSDAEVDAAMTNICRCGTYPRIRAAIRLAARVMRGEERIAAAPP
PGIRPEDAARAVPALRPES

Sequences:

>Translated_179_residues
MTRFSVNDRPVEYRMEPETPLLWALRDASNLTGTKYGCGTGDCGACTVDIDGEAIRSCLVTIAECEGRFVTTIEGLTRDR
SHPVQQAWVAEQVPQCGFCQSGMIMAAAVLLRKNSNPSDAEVDAAMTNICRCGTYPRIRAAIRLAARVMRGEERIAAAPP
PGIRPEDAARAVPALRPES
>Mature_178_residues
TRFSVNDRPVEYRMEPETPLLWALRDASNLTGTKYGCGTGDCGACTVDIDGEAIRSCLVTIAECEGRFVTTIEGLTRDRS
HPVQQAWVAEQVPQCGFCQSGMIMAAAVLLRKNSNPSDAEVDAAMTNICRCGTYPRIRAAIRLAARVMRGEERIAAAPPP
GIRPEDAARAVPALRPES

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=158, Percent_Identity=40.5063291139241, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI71773480, Length=146, Percent_Identity=45.8904109589041, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786480, Length=160, Percent_Identity=37.5, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789232, Length=139, Percent_Identity=41.0071942446043, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540638, Length=151, Percent_Identity=40.3973509933775, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=152, Percent_Identity=37.5, Blast_Score=105, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32566215, Length=152, Percent_Identity=36.8421052631579, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17737937, Length=146, Percent_Identity=39.7260273972603, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24647199, Length=153, Percent_Identity=33.9869281045752, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647195, Length=158, Percent_Identity=33.5443037974684, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647197, Length=158, Percent_Identity=33.5443037974684, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647193, Length=133, Percent_Identity=35.3383458646617, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647201, Length=153, Percent_Identity=31.3725490196078, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 19396; Mature: 19265

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFSVNDRPVEYRMEPETPLLWALRDASNLTGTKYGCGTGDCGACTVDIDGEAIRSCLV
CCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
TIAECEGRFVTTIEGLTRDRSHPVQQAWVAEQVPQCGFCQSGMIMAAAVLLRKNSNPSDA
HHHHCCCCEEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCH
EVDAAMTNICRCGTYPRIRAAIRLAARVMRGEERIAAAPPPGIRPEDAARAVPALRPES
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
TRFSVNDRPVEYRMEPETPLLWALRDASNLTGTKYGCGTGDCGACTVDIDGEAIRSCLV
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHH
TIAECEGRFVTTIEGLTRDRSHPVQQAWVAEQVPQCGFCQSGMIMAAAVLLRKNSNPSDA
HHHHCCCCEEEEHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCH
EVDAAMTNICRCGTYPRIRAAIRLAARVMRGEERIAAAPPPGIRPEDAARAVPALRPES
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]