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The map label for this gene is betP [H]

Identifier: 103486417

GI number: 103486417

Start: 942145

End: 943695

Strand: Reverse

Name: betP [H]

Synonym: Sala_0927

Alternate gene names: 103486417

Gene position: 943695-942145 (Counterclockwise)

Preceding gene: 103486420

Following gene: 103486416

Centisome position: 28.21

GC content: 66.86

Gene sequence:

>1551_bases
ATGCGATTGGACCCGCATTTGCCCGTCTCGCCGAAAAATTCGCTCAATCGCCCGGTCTTTTTCGTGCCTCTCATGGTGTT
GCTCGCTACCGTGATGCTCAGCCTGTGGCGGGGCGAAGCGGTCGTCACCGCCGAGACGGTGATCAACAACTGGATTCTGC
GCCATTTTTCGCCTCTTTTCGCGGGAGCGGCCATCGCCTTCCTTGTGCTACTCCTGCTCGTGGCGCTGTCACCGCTTGGC
GGCCGTATCATCGGCGGCACGATGGCGACGCCGCTCCTGACGCGCTGGCGCTGGTTTGCGGTCACGCTCTGCACCACGAT
CGCCACCGGCATCCTTTTCTGGGGCGCGGCCGAACCGCTCTTCCATCTCAATGACCCGCCCGCAATGCTGGGGATCGAGC
CGGGCAGCGATGCCGCCGCAACCTTCGCCATGTCGACGATGTTCCTCCACTGGACGCTGACGCCCTATGCAATTTACACC
GTGGCGGGCCTGACCTTCGCGCTTGTCTATTATGATCGCCGCGAACCCTTCAGCCTCTCGTCGCTCTTCGTACCCCTTGT
CGGTCAGCGCGCGCACGGCGCCGCAGGCACCGCGGTCGACATCCTCTGCCTGTTCGCGCTGGTCGCAGGCATGGCCGCCT
CGCTCGGCGCGGGCGTACTCGCACTGGCCGGTGGAATCGAGGGTCTGTGGGGCATCGCCGGCGGAGCGCCGCTGCGCTGG
GGCATCGCGGCAGCGATCGTGGGCACCTTTGTCGTCTCCGCCGCGCTTGGTCTCCAGCGCGGTATTGCGCGGCTGTCGCT
GCTCAACATCTGGTTGTTCGCCGCCGTGCTGTTGTTCGTTGTGGTCGCCGGGCCCGCCGCCCGCCTTCCGGGCCTGGGCC
TGGCGGGCGTCGCCGATTATGTCGCAACCTTTGCGCCGCGCAGCCTCGGCCTCGACGTCGATTCCGACTGGCACCGGCAA
TGGACGATCTTCAACTGGGCCAACTGGATTGCCTGGGCGCCGGTCACGGCGCTCTTTCTCGGCCGGCTCGCGGTCGGCTA
CAGCGTGCGCGCCTTCATCCTCGTCAACCTGCTGCTGCCGGCGCTGTTCGGCGCGGCGTGGATGATCGTCATTGCCGGGA
CAACGATCACCCTCGACCAGCAATCGGGCGGCAGCCTTTACACCGTGCTCACGAGCGCCGGTCCCGACCCCCTCCTCTAT
CGCCTGTTCAGCGCGCTCGGGGGCGGCGTGCCCGTGCTCATGCTGCTGATCGGCGCGATCTTCATTTCCTATGTGACCGC
GGCCGACAGCAATGTCTCGGCGATGAGCGCGCTCTCGACGCACGGCATTTCGCCCGAAACACCCGAAGCCCCCCTCGCGG
TCAAGGCGGCCTGGGGGATCACCGTCGGGCTGGTCGCGACCATCCTTGTCGCTGCGGCGGGGATCGACGGCATCCGCATG
ATGTCGGTGCTCGGCGGTTTCCCGGCGCTGTTCATCATCCTTGGCGCCGCCGCCTCGCTGGCGGTGATGGCGATCGGGCG
ACAACCGCTCACGGCCCCGGCGGATCGCTGA

Upstream 100 bases:

>100_bases
CTTTGGTCCCTTGCTCCCTTTTCAACGTTCGGCGTCGCTGCACGTTCCGCCTTTGATTTGACCTGTTCCCGGCCAACCGC
CATGCTGGACGAAATCCCAT

Downstream 100 bases:

>100_bases
CCAAAAGGGCACGTTGCCGCCGCGCACCCTGCGCCCTATTTATGCGGAGGCGCGGTATAAACCCTCCTTGCGCGTTTAGA
ACAAATCTGGAACATACGCC

Product: BCCT transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MRLDPHLPVSPKNSLNRPVFFVPLMVLLATVMLSLWRGEAVVTAETVINNWILRHFSPLFAGAAIAFLVLLLLVALSPLG
GRIIGGTMATPLLTRWRWFAVTLCTTIATGILFWGAAEPLFHLNDPPAMLGIEPGSDAAATFAMSTMFLHWTLTPYAIYT
VAGLTFALVYYDRREPFSLSSLFVPLVGQRAHGAAGTAVDILCLFALVAGMAASLGAGVLALAGGIEGLWGIAGGAPLRW
GIAAAIVGTFVVSAALGLQRGIARLSLLNIWLFAAVLLFVVVAGPAARLPGLGLAGVADYVATFAPRSLGLDVDSDWHRQ
WTIFNWANWIAWAPVTALFLGRLAVGYSVRAFILVNLLLPALFGAAWMIVIAGTTITLDQQSGGSLYTVLTSAGPDPLLY
RLFSALGGGVPVLMLLIGAIFISYVTAADSNVSAMSALSTHGISPETPEAPLAVKAAWGITVGLVATILVAAAGIDGIRM
MSVLGGFPALFIILGAAASLAVMAIGRQPLTAPADR

Sequences:

>Translated_516_residues
MRLDPHLPVSPKNSLNRPVFFVPLMVLLATVMLSLWRGEAVVTAETVINNWILRHFSPLFAGAAIAFLVLLLLVALSPLG
GRIIGGTMATPLLTRWRWFAVTLCTTIATGILFWGAAEPLFHLNDPPAMLGIEPGSDAAATFAMSTMFLHWTLTPYAIYT
VAGLTFALVYYDRREPFSLSSLFVPLVGQRAHGAAGTAVDILCLFALVAGMAASLGAGVLALAGGIEGLWGIAGGAPLRW
GIAAAIVGTFVVSAALGLQRGIARLSLLNIWLFAAVLLFVVVAGPAARLPGLGLAGVADYVATFAPRSLGLDVDSDWHRQ
WTIFNWANWIAWAPVTALFLGRLAVGYSVRAFILVNLLLPALFGAAWMIVIAGTTITLDQQSGGSLYTVLTSAGPDPLLY
RLFSALGGGVPVLMLLIGAIFISYVTAADSNVSAMSALSTHGISPETPEAPLAVKAAWGITVGLVATILVAAAGIDGIRM
MSVLGGFPALFIILGAAASLAVMAIGRQPLTAPADR
>Mature_516_residues
MRLDPHLPVSPKNSLNRPVFFVPLMVLLATVMLSLWRGEAVVTAETVINNWILRHFSPLFAGAAIAFLVLLLLVALSPLG
GRIIGGTMATPLLTRWRWFAVTLCTTIATGILFWGAAEPLFHLNDPPAMLGIEPGSDAAATFAMSTMFLHWTLTPYAIYT
VAGLTFALVYYDRREPFSLSSLFVPLVGQRAHGAAGTAVDILCLFALVAGMAASLGAGVLALAGGIEGLWGIAGGAPLRW
GIAAAIVGTFVVSAALGLQRGIARLSLLNIWLFAAVLLFVVVAGPAARLPGLGLAGVADYVATFAPRSLGLDVDSDWHRQ
WTIFNWANWIAWAPVTALFLGRLAVGYSVRAFILVNLLLPALFGAAWMIVIAGTTITLDQQSGGSLYTVLTSAGPDPLLY
RLFSALGGGVPVLMLLIGAIFISYVTAADSNVSAMSALSTHGISPETPEAPLAVKAAWGITVGLVATILVAAAGIDGIRM
MSVLGGFPALFIILGAAASLAVMAIGRQPLTAPADR

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=519, Percent_Identity=26.7822736030828, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786224, Length=492, Percent_Identity=25.2032520325203, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788102, Length=435, Percent_Identity=25.5172413793103, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 53961; Mature: 53961

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDPHLPVSPKNSLNRPVFFVPLMVLLATVMLSLWRGEAVVTAETVINNWILRHFSPLF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
AGAAIAFLVLLLLVALSPLGGRIIGGTMATPLLTRWRWFAVTLCTTIATGILFWGAAEPL
HHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FHLNDPPAMLGIEPGSDAAATFAMSTMFLHWTLTPYAIYTVAGLTFALVYYDRREPFSLS
EECCCCCCEEEECCCCCHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHEECCCCCCCHH
SLFVPLVGQRAHGAAGTAVDILCLFALVAGMAASLGAGVLALAGGIEGLWGIAGGAPLRW
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHCCCCCCHHH
GIAAAIVGTFVVSAALGLQRGIARLSLLNIWLFAAVLLFVVVAGPAARLPGLGLAGVADY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHH
VATFAPRSLGLDVDSDWHRQWTIFNWANWIAWAPVTALFLGRLAVGYSVRAFILVNLLLP
HHHHCCHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFGAAWMIVIAGTTITLDQQSGGSLYTVLTSAGPDPLLYRLFSALGGGVPVLMLLIGAI
HHHHHHHHHHEECCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHH
FISYVTAADSNVSAMSALSTHGISPETPEAPLAVKAAWGITVGLVATILVAAAGIDGIRM
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHH
MSVLGGFPALFIILGAAASLAVMAIGRQPLTAPADR
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRLDPHLPVSPKNSLNRPVFFVPLMVLLATVMLSLWRGEAVVTAETVINNWILRHFSPLF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
AGAAIAFLVLLLLVALSPLGGRIIGGTMATPLLTRWRWFAVTLCTTIATGILFWGAAEPL
HHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FHLNDPPAMLGIEPGSDAAATFAMSTMFLHWTLTPYAIYTVAGLTFALVYYDRREPFSLS
EECCCCCCEEEECCCCCHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHEECCCCCCCHH
SLFVPLVGQRAHGAAGTAVDILCLFALVAGMAASLGAGVLALAGGIEGLWGIAGGAPLRW
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHCCCCCCHHH
GIAAAIVGTFVVSAALGLQRGIARLSLLNIWLFAAVLLFVVVAGPAARLPGLGLAGVADY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHH
VATFAPRSLGLDVDSDWHRQWTIFNWANWIAWAPVTALFLGRLAVGYSVRAFILVNLLLP
HHHHCCHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALFGAAWMIVIAGTTITLDQQSGGSLYTVLTSAGPDPLLYRLFSALGGGVPVLMLLIGAI
HHHHHHHHHHEECCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHH
FISYVTAADSNVSAMSALSTHGISPETPEAPLAVKAAWGITVGLVATILVAAAGIDGIRM
HHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHH
MSVLGGFPALFIILGAAASLAVMAIGRQPLTAPADR
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]