Click here to switch to the map view.

The map label for this gene is hsaB [H]

Identifier: 103486380

GI number: 103486380

Start: 897485

End: 898711

Strand: Direct

Name: hsaB [H]

Synonym: Sala_0890

Alternate gene names: 103486380

Gene position: 897485-898711 (Clockwise)

Preceding gene: 103486379

Following gene: 103486381

Centisome position: 26.83

GC content: 66.67

Gene sequence:

>1227_bases
ATGAGTGTTACCGAATATCGCGGCTTTGCGGGTGTCCGGCTGGAAGCCGAAATCCGGGGTTCGGCGGATGATCCCGCGGT
GCTGCTGGTGCATGGCGCCGGTCAGACGCGCGGCGTGTGGTCAGGGGTTGCCGAGGCGCTTGAGCGGGCGGGACGGCGGG
TGATCAGCCTCGACCTGCGCGGGCATGGCGGCAGCGAATGGCCCGCCGACGGACGTTATGATTTCGATGCGATGGTCGAG
GATCTGCGCGCAGTGCTCGCCCAGCTCGGTAGTCGGCCCGTCGTCGTCGCGGCCACGCTGGGCGGCTGGATCGCGACCGC
CGCCCTGGAACGCGACGCCGCGCTTCTGGCATCGGGTCTGGTGCTCGTCGACGTGCCGCTCGCGCTCGATGCCGAGGTGG
CGCGGCGTATCGGCGCGCGCCTGCGCGAGGCAGCAACGCTGGCGCCAGGACAGGCGCAATGGGACAGCCGGTTGCTCGAC
GCCTTCGATAGCGAGGCGGTGGTCGAACGGCTGGCGGGGGCGCCCCGGGCGATTGCGCTGCCGACCCTCTATGTCCGCGG
GGGGCTTTCCGAACTGGTGCCGTCCGATGACGCGGCGGCCTTTGTCGCGACATTCCCCGACGGTGAGCTTGCCGAGGTCG
AGGATCGGGCATTCGTCGTTGCCGACGACCGCAGCGAGGCATTTGGTGGCTATCTTATCGACTTCCTTGAACGCCGCGCG
CCGCGCGCGTCACCCGAGTATCGCGAGGGGTCGGATGCGCGCAGCTTTCGCGACGCGCTCGGCTGTTTCGCGACCGGCGT
GACCGTCGTGACCGCAATGTGCCCCGACGGAACGCCGGTCGGCCTGACCGCCAACAGCTTCACATCGGTCTCGCTCGATC
CCCCGCTGTTGCTCGTATGTATCGCCAACAGCGCGGGAAGCGCGCCCTTTCTGCGCAAAGCCGATCGCTTTGCGGTCAAT
GTCCTGCAAATCGGACAACAGCCGACCTCGAACCGCTTTGCGGGCAAGGGAGAAGACCGCTTCGGCGCGACGCCCTGGAT
GGTGGGCGAATTCGGCACGCCAGTGCTGACCGGGTCGCTCTCCAGCTTTGAATGCGCGCGCGAAGCGGTGCATGACGGTG
GCGATCATTTCATCCTCGTCGGTCGCGTTCTGAAGGCGATTTTCGAACCTCGCCGGGACCCGCTTCTCTATTTTCGCGGA
AAATATCGCAAATTGCATTTCGCGTGA

Upstream 100 bases:

>100_bases
CTATCGCCGACGGCGATCCCGAAGTCGCCCGGCTCATGATGCGGCGGCGGTCGGCTCTGTTCGATAGCTGGCTGGAACCT
GACCGAAGGGAAGACACGGC

Downstream 100 bases:

>100_bases
GGGCTGGACAAACCGCTTCAAGCTTCATATCAAACCTAGTTATACAAGTAAGAAGGGAAGCGGATGGCCTGGGTACATCA
GGACAAGTGCGCCATCGTTG

Product: flavin reductase-like, FMN-binding

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSVTEYRGFAGVRLEAEIRGSADDPAVLLVHGAGQTRGVWSGVAEALERAGRRVISLDLRGHGGSEWPADGRYDFDAMVE
DLRAVLAQLGSRPVVVAATLGGWIATAALERDAALLASGLVLVDVPLALDAEVARRIGARLREAATLAPGQAQWDSRLLD
AFDSEAVVERLAGAPRAIALPTLYVRGGLSELVPSDDAAAFVATFPDGELAEVEDRAFVVADDRSEAFGGYLIDFLERRA
PRASPEYREGSDARSFRDALGCFATGVTVVTAMCPDGTPVGLTANSFTSVSLDPPLLLVCIANSAGSAPFLRKADRFAVN
VLQIGQQPTSNRFAGKGEDRFGATPWMVGEFGTPVLTGSLSSFECAREAVHDGGDHFILVGRVLKAIFEPRRDPLLYFRG
KYRKLHFA

Sequences:

>Translated_408_residues
MSVTEYRGFAGVRLEAEIRGSADDPAVLLVHGAGQTRGVWSGVAEALERAGRRVISLDLRGHGGSEWPADGRYDFDAMVE
DLRAVLAQLGSRPVVVAATLGGWIATAALERDAALLASGLVLVDVPLALDAEVARRIGARLREAATLAPGQAQWDSRLLD
AFDSEAVVERLAGAPRAIALPTLYVRGGLSELVPSDDAAAFVATFPDGELAEVEDRAFVVADDRSEAFGGYLIDFLERRA
PRASPEYREGSDARSFRDALGCFATGVTVVTAMCPDGTPVGLTANSFTSVSLDPPLLLVCIANSAGSAPFLRKADRFAVN
VLQIGQQPTSNRFAGKGEDRFGATPWMVGEFGTPVLTGSLSSFECAREAVHDGGDHFILVGRVLKAIFEPRRDPLLYFRG
KYRKLHFA
>Mature_407_residues
SVTEYRGFAGVRLEAEIRGSADDPAVLLVHGAGQTRGVWSGVAEALERAGRRVISLDLRGHGGSEWPADGRYDFDAMVED
LRAVLAQLGSRPVVVAATLGGWIATAALERDAALLASGLVLVDVPLALDAEVARRIGARLREAATLAPGQAQWDSRLLDA
FDSEAVVERLAGAPRAIALPTLYVRGGLSELVPSDDAAAFVATFPDGELAEVEDRAFVVADDRSEAFGGYLIDFLERRAP
RASPEYREGSDARSFRDALGCFATGVTVVTAMCPDGTPVGLTANSFTSVSLDPPLLLVCIANSAGSAPFLRKADRFAVNV
LQIGQQPTSNRFAGKGEDRFGATPWMVGEFGTPVLTGSLSSFECAREAVHDGGDHFILVGRVLKAIFEPRRDPLLYFRGK
YRKLHFA

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=156, Percent_Identity=35.8974358974359, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 43531; Mature: 43399

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTEYRGFAGVRLEAEIRGSADDPAVLLVHGAGQTRGVWSGVAEALERAGRRVISLDLR
CCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEE
GHGGSEWPADGRYDFDAMVEDLRAVLAQLGSRPVVVAATLGGWIATAALERDAALLASGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCE
VLVDVPLALDAEVARRIGARLREAATLAPGQAQWDSRLLDAFDSEAVVERLAGAPRAIAL
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEC
PTLYVRGGLSELVPSDDAAAFVATFPDGELAEVEDRAFVVADDRSEAFGGYLIDFLERRA
CCCEECCCHHHHCCCCCCCEEEEECCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHCC
PRASPEYREGSDARSFRDALGCFATGVTVVTAMCPDGTPVGLTANSFTSVSLDPPLLLVC
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECCCCEEEECCCCEEEEE
IANSAGSAPFLRKADRFAVNVLQIGQQPTSNRFAGKGEDRFGATPWMVGEFGTPVLTGSL
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCC
SSFECAREAVHDGGDHFILVGRVLKAIFEPRRDPLLYFRGKYRKLHFA
HHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCEEEEECCCEEECCC
>Mature Secondary Structure 
SVTEYRGFAGVRLEAEIRGSADDPAVLLVHGAGQTRGVWSGVAEALERAGRRVISLDLR
CCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEE
GHGGSEWPADGRYDFDAMVEDLRAVLAQLGSRPVVVAATLGGWIATAALERDAALLASGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCE
VLVDVPLALDAEVARRIGARLREAATLAPGQAQWDSRLLDAFDSEAVVERLAGAPRAIAL
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEC
PTLYVRGGLSELVPSDDAAAFVATFPDGELAEVEDRAFVVADDRSEAFGGYLIDFLERRA
CCCEECCCHHHHCCCCCCCEEEEECCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHHCC
PRASPEYREGSDARSFRDALGCFATGVTVVTAMCPDGTPVGLTANSFTSVSLDPPLLLVC
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEECCCCEEEECCCCEEEEE
IANSAGSAPFLRKADRFAVNVLQIGQQPTSNRFAGKGEDRFGATPWMVGEFGTPVLTGSL
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEECCC
SSFECAREAVHDGGDHFILVGRVLKAIFEPRRDPLLYFRGKYRKLHFA
HHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCEEEEECCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA