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The map label for this gene is nanR [H]

Identifier: 103486358

GI number: 103486358

Start: 874496

End: 875272

Strand: Direct

Name: nanR [H]

Synonym: Sala_0868

Alternate gene names: 103486358

Gene position: 874496-875272 (Clockwise)

Preceding gene: 103486357

Following gene: 103486359

Centisome position: 26.14

GC content: 60.49

Gene sequence:

>777_bases
TTGCAGATGGATAATGGCAACGCGCGAATCCGGGTTCCGAAAACGTCGGAACTGGTCGCCGACCAGATCAGGGCGCAAAT
CATCCGCGGCGAACTTCAGGAAGGTGACTCGCTGCCCCCCGAAGGAACGTTGATGGCGACCCTGGGCATTTCGCGCCCGA
CGCTGCGCGAAGCCTTTCGCATCCTGGAGGCGGAAAGTCTGATCAGCGTGGTGCGCGGATCGCGAAGCGGCGCGCGGGTG
CATCAACCCTCCACCGAACTTGTGTCCCGCTACGCCGGATATGTGCTGGAATCGCAAGGGACGACCATCGCCGATCTGTA
TGCGGCGCGGCTGGCGATCGAACCCACTGTCGTGCGCTGGCTTGCGACATCGAAGGGGCAGACCCCCGGCATGGCACGGG
TGAAGGACATATTGGCCGAACTGGAGGATATGCTCCAGACCGACCGCCACGCCGAGTTCGTCGACAATATCGCGGTTTTT
CACCAGGCCTTGGTCGAAGCGACGGGCAACAACACGCTGAGTTTCATGAACCGGATGTTGCTCAACCTCGCACGCAATCA
TCAGAATGATTATCAGCGCCGCCATCCGCGATCGAACGAGGAGAAGTACAAGAGCCTGCGCGCCGGTTTCAAATCCTATG
TCAAACTGGTCAAGATGATCGAAGAAGGCGATGTCGAAGGCGCGGTGGCGCACTGGCGCCTTCACCTTCGCAACGCCAAT
GAAACCTGGGCGCAGCGCGGTGAGGGCGAGCGGATCGTCGATTCCCTGCACGCATGA

Upstream 100 bases:

>100_bases
CGCGGGCGGAAGCAGCCGCATTGCGGGGGCGCCGGAAAGGCCTTAAAGGCACGATCTGGTCCGCACGGAATGACGGCGTA
TCGGCACAAGGGGCAAGATT

Downstream 100 bases:

>100_bases
CGGCATCGTTCATCGATGCGATGATCGCGGCGGCGGCGCGTGCGCCGCAGGCGTCGCTGATCGTCGCATCGGACATGCGC
CCGTGTGATACCACGCTCGG

Product: regulatory protein GntR, HTH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MQMDNGNARIRVPKTSELVADQIRAQIIRGELQEGDSLPPEGTLMATLGISRPTLREAFRILEAESLISVVRGSRSGARV
HQPSTELVSRYAGYVLESQGTTIADLYAARLAIEPTVVRWLATSKGQTPGMARVKDILAELEDMLQTDRHAEFVDNIAVF
HQALVEATGNNTLSFMNRMLLNLARNHQNDYQRRHPRSNEEKYKSLRAGFKSYVKLVKMIEEGDVEGAVAHWRLHLRNAN
ETWAQRGEGERIVDSLHA

Sequences:

>Translated_258_residues
MQMDNGNARIRVPKTSELVADQIRAQIIRGELQEGDSLPPEGTLMATLGISRPTLREAFRILEAESLISVVRGSRSGARV
HQPSTELVSRYAGYVLESQGTTIADLYAARLAIEPTVVRWLATSKGQTPGMARVKDILAELEDMLQTDRHAEFVDNIAVF
HQALVEATGNNTLSFMNRMLLNLARNHQNDYQRRHPRSNEEKYKSLRAGFKSYVKLVKMIEEGDVEGAVAHWRLHLRNAN
ETWAQRGEGERIVDSLHA
>Mature_258_residues
MQMDNGNARIRVPKTSELVADQIRAQIIRGELQEGDSLPPEGTLMATLGISRPTLREAFRILEAESLISVVRGSRSGARV
HQPSTELVSRYAGYVLESQGTTIADLYAARLAIEPTVVRWLATSKGQTPGMARVKDILAELEDMLQTDRHAEFVDNIAVF
HQALVEATGNNTLSFMNRMLLNLARNHQNDYQRRHPRSNEEKYKSLRAGFKSYVKLVKMIEEGDVEGAVAHWRLHLRNAN
ETWAQRGEGERIVDSLHA

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=243, Percent_Identity=27.9835390946502, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28983; Mature: 28983

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMDNGNARIRVPKTSELVADQIRAQIIRGELQEGDSLPPEGTLMATLGISRPTLREAFR
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHH
ILEAESLISVVRGSRSGARVHQPSTELVSRYAGYVLESQGTTIADLYAARLAIEPTVVRW
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCHHHHHH
LATSKGQTPGMARVKDILAELEDMLQTDRHAEFVDNIAVFHQALVEATGNNTLSFMNRML
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNLARNHQNDYQRRHPRSNEEKYKSLRAGFKSYVKLVKMIEEGDVEGAVAHWRLHLRNAN
HHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCC
ETWAQRGEGERIVDSLHA
HHHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MQMDNGNARIRVPKTSELVADQIRAQIIRGELQEGDSLPPEGTLMATLGISRPTLREAFR
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHH
ILEAESLISVVRGSRSGARVHQPSTELVSRYAGYVLESQGTTIADLYAARLAIEPTVVRW
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCHHHHHH
LATSKGQTPGMARVKDILAELEDMLQTDRHAEFVDNIAVFHQALVEATGNNTLSFMNRML
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNLARNHQNDYQRRHPRSNEEKYKSLRAGFKSYVKLVKMIEEGDVEGAVAHWRLHLRNAN
HHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCC
ETWAQRGEGERIVDSLHA
HHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA