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The map label for this gene is dgoD1 [H]

Identifier: 103486234

GI number: 103486234

Start: 749522

End: 750658

Strand: Reverse

Name: dgoD1 [H]

Synonym: Sala_0742

Alternate gene names: 103486234

Gene position: 750658-749522 (Counterclockwise)

Preceding gene: 103486240

Following gene: 103486233

Centisome position: 22.44

GC content: 58.93

Gene sequence:

>1137_bases
ATGAAAATTGCCCGAATAGAAACATTTCATGTCCCGCCACGCTGGCTGTTTGTACGAATTGAAGCCGACAACGGCACAAT
CGGATGGGGCGAAGCCAGCCTGGAAGGCCATGCCGAAGCCGTGGACGGCGCACTTGACGCGATGCGGGATCGATTCATCG
GCGCGGATCCCCGGAAAATAGAGGATATCTGGCAAGTCGCGTATCGGGGAGGCTTTTATCGGGGTGGGCCGGTCCTGATG
TCGGCGCTCGCTGGCCTTGATCAGGCTTTGTGGGATCTAAAGGGACGACATTACGGGCTTCCGGCGTGGGAGATGCTTGG
CGGCAAGGTTCGCGACAAGGTGCGCGCATATGCGTGGATCGGCGGCGATCGACCCGATGATATCGCCAACGCGGCCAAGG
CTCGGCGACAACAGGGATTCACGGCAATAAAAATGAACGCCACGTCCGAGATCGATTATCTGACCGCGCCCAAACTCGAT
GACGTGGTGGAGCGTGTTCGTGCGGCCCAGAATGAAGGGCTCGACGTGGGCGTGGATTTTCATGGTCGGGTCCACAGACC
CATGGCCAAGCAGCTCGCAAAACTGCTCGAACCGCTTGGACTTCTGTTCATCGAGGAGCCCATATTATCCGAGAATCCCG
AGGCGCTCTCGCAGCTGGCCGGACTTGTGAGTACCCCGATCGCGGTGGGCGAACGCCTTTATTCGCGCTGGGACTTCAAA
CCTTTCCTCGCGAGTGGCGCTGTCGATATCATCCAGCCCGACCTGAGCCATGCCGGTGGTTTGACCGAATGCCGCAAGAT
TGCGGCAATGGCCGAGTCTTACGACGTGGCGGTGGCCCCGCATTGCCCGCTTGGTCCTCTTGCGCTCGGAGCATGCCTTC
AGCTCGCGGCCTGCACGCCCAACGTCATCATCCAGGAAATGTCGTTGGGCATCCACTATAATGAAACGCACGACCTGCTC
AGCTTTTGCGCAAATCCGGACGTTCTGACGCCAGAAGAGGGCTTCCTGGCTATTCCGGAAGGACCGGGCCTCGGCATTGA
AATCGACGAGATAAAAGTGCGCGAAGCCGCCAAAAACCGTCATCGCTGGCGGAATCCAATCTGGCGGCATGCAGATGGCA
GCGTGGCAGAATGGTGA

Upstream 100 bases:

>100_bases
CCGCCGTCGCTGGCACGAAATCCCGATATCTATTGCGCTATATGTATTATCATATAAATGTGCAATCCGCGTTTGTCGTG
ATGGAAGCGAGCCCGTCTTT

Downstream 100 bases:

>100_bases
CAGTCGCCTCAAAAATTGACCTTGGATAATATAAATCATACAAATGACTTGCTGATAGGCGGATCGATCGATTATAGCCT
TCGCAAGAGCCGGGAATGCG

Product: galactonate dehydratase

Products: NA

Alternate protein names: GalD 1 [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKIARIETFHVPPRWLFVRIEADNGTIGWGEASLEGHAEAVDGALDAMRDRFIGADPRKIEDIWQVAYRGGFYRGGPVLM
SALAGLDQALWDLKGRHYGLPAWEMLGGKVRDKVRAYAWIGGDRPDDIANAAKARRQQGFTAIKMNATSEIDYLTAPKLD
DVVERVRAAQNEGLDVGVDFHGRVHRPMAKQLAKLLEPLGLLFIEEPILSENPEALSQLAGLVSTPIAVGERLYSRWDFK
PFLASGAVDIIQPDLSHAGGLTECRKIAAMAESYDVAVAPHCPLGPLALGACLQLAACTPNVIIQEMSLGIHYNETHDLL
SFCANPDVLTPEEGFLAIPEGPGLGIEIDEIKVREAAKNRHRWRNPIWRHADGSVAEW

Sequences:

>Translated_378_residues
MKIARIETFHVPPRWLFVRIEADNGTIGWGEASLEGHAEAVDGALDAMRDRFIGADPRKIEDIWQVAYRGGFYRGGPVLM
SALAGLDQALWDLKGRHYGLPAWEMLGGKVRDKVRAYAWIGGDRPDDIANAAKARRQQGFTAIKMNATSEIDYLTAPKLD
DVVERVRAAQNEGLDVGVDFHGRVHRPMAKQLAKLLEPLGLLFIEEPILSENPEALSQLAGLVSTPIAVGERLYSRWDFK
PFLASGAVDIIQPDLSHAGGLTECRKIAAMAESYDVAVAPHCPLGPLALGACLQLAACTPNVIIQEMSLGIHYNETHDLL
SFCANPDVLTPEEGFLAIPEGPGLGIEIDEIKVREAAKNRHRWRNPIWRHADGSVAEW
>Mature_378_residues
MKIARIETFHVPPRWLFVRIEADNGTIGWGEASLEGHAEAVDGALDAMRDRFIGADPRKIEDIWQVAYRGGFYRGGPVLM
SALAGLDQALWDLKGRHYGLPAWEMLGGKVRDKVRAYAWIGGDRPDDIANAAKARRQQGFTAIKMNATSEIDYLTAPKLD
DVVERVRAAQNEGLDVGVDFHGRVHRPMAKQLAKLLEPLGLLFIEEPILSENPEALSQLAGLVSTPIAVGERLYSRWDFK
PFLASGAVDIIQPDLSHAGGLTECRKIAAMAESYDVAVAPHCPLGPLALGACLQLAACTPNVIIQEMSLGIHYNETHDLL
SFCANPDVLTPEEGFLAIPEGPGLGIEIDEIKVREAAKNRHRWRNPIWRHADGSVAEW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=382, Percent_Identity=52.0942408376963, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787864, Length=417, Percent_Identity=32.8537170263789, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI226510960, Length=272, Percent_Identity=30.1470588235294, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 41544; Mature: 41544

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIARIETFHVPPRWLFVRIEADNGTIGWGEASLEGHAEAVDGALDAMRDRFIGADPRKI
CCCEEEEEEECCCEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
EDIWQVAYRGGFYRGGPVLMSALAGLDQALWDLKGRHYGLPAWEMLGGKVRDKVRAYAWI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHEEEEE
GGDRPDDIANAAKARRQQGFTAIKMNATSEIDYLTAPKLDDVVERVRAAQNEGLDVGVDF
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECC
HGRVHRPMAKQLAKLLEPLGLLFIEEPILSENPEALSQLAGLVSTPIAVGERLYSRWDFK
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PFLASGAVDIIQPDLSHAGGLTECRKIAAMAESYDVAVAPHCPLGPLALGACLQLAACTP
HHHHCCCHHHCCCCHHHCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCH
NVIIQEMSLGIHYNETHDLLSFCANPDVLTPEEGFLAIPEGPGLGIEIDEIKVREAAKNR
HHHHHHHHCCEEECCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHH
HRWRNPIWRHADGSVAEW
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKIARIETFHVPPRWLFVRIEADNGTIGWGEASLEGHAEAVDGALDAMRDRFIGADPRKI
CCCEEEEEEECCCEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
EDIWQVAYRGGFYRGGPVLMSALAGLDQALWDLKGRHYGLPAWEMLGGKVRDKVRAYAWI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHEEEEE
GGDRPDDIANAAKARRQQGFTAIKMNATSEIDYLTAPKLDDVVERVRAAQNEGLDVGVDF
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECC
HGRVHRPMAKQLAKLLEPLGLLFIEEPILSENPEALSQLAGLVSTPIAVGERLYSRWDFK
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PFLASGAVDIIQPDLSHAGGLTECRKIAAMAESYDVAVAPHCPLGPLALGACLQLAACTP
HHHHCCCHHHCCCCHHHCCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCH
NVIIQEMSLGIHYNETHDLLSFCANPDVLTPEEGFLAIPEGPGLGIEIDEIKVREAAKNR
HHHHHHHHCCEEECCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEHHHHHHHHHHHH
HRWRNPIWRHADGSVAEW
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA