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The map label for this gene is aacC1 [H]

Identifier: 103486119

GI number: 103486119

Start: 638262

End: 638720

Strand: Reverse

Name: aacC1 [H]

Synonym: Sala_0626

Alternate gene names: 103486119

Gene position: 638720-638262 (Counterclockwise)

Preceding gene: 103486120

Following gene: 103486118

Centisome position: 19.09

GC content: 69.28

Gene sequence:

>459_bases
ATGATCGTCCGCCGCCTCGGCCCCGGCGACATCGCCGCAGTGCGCGCGCTGAACGCGGTCTATGGCGCCGCCTTCGACGA
CCCCGAAACCTATCGCGCCGACCGTCCCGACGACGCATGGCTGGCGCGCCAGCTTGGCCGCGAGGGGGTGATCGTGCTGG
TCGCCGAACTGGACGGCAACATCGTCGGCGGCCTCACCGCCTATGAGCTACCGAAGCTTGAGGCGGCGCGCAGCGAAATC
TATCTCTATGACCTCGCGGTCGATGCCGCGCACCGCCGCTGCGGTATCGCCACCGCGCTGATCGGGGAGCTTCAACATAT
CGCCGCCGAAACCGGCGCCTGGGCGGTGTTCGTCCAGGCCGACCATGGCGACGACCCCGCGGTTGCGTTATACACCGGGC
TCGGCGCGCGCGAGGATGTGATGCATTTCGACCTGCCCCCGCGACCGCGCGGCGCATAG

Upstream 100 bases:

>100_bases
CCGCAAAAATCCTTCTCCCGGGCTCGGGCGGGTTGGGTCGCGAGTTCGTGATTTCGGCCAGGCGGCTCGGCTGGCAGGGC
GTCGAGCGGTGGCGCGCGCG

Downstream 100 bases:

>100_bases
GAAGAAAGCGGAACCATCGCGCTAGGCCGCCCCCTTTCCCCCTGCTACACCGCCCGCCATGTCCGAGAAGAATCACCTCT
ATCTGGTCGATGGCTCCAGC

Product: gentamicin 3'-N-acetyltransferase

Products: NA

Alternate protein names: AAC(3)-I; Aminoglycoside N(3')-acetyltransferase I; Gentamicin acetyltransferase I [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MIVRRLGPGDIAAVRALNAVYGAAFDDPETYRADRPDDAWLARQLGREGVIVLVAELDGNIVGGLTAYELPKLEAARSEI
YLYDLAVDAAHRRCGIATALIGELQHIAAETGAWAVFVQADHGDDPAVALYTGLGAREDVMHFDLPPRPRGA

Sequences:

>Translated_152_residues
MIVRRLGPGDIAAVRALNAVYGAAFDDPETYRADRPDDAWLARQLGREGVIVLVAELDGNIVGGLTAYELPKLEAARSEI
YLYDLAVDAAHRRCGIATALIGELQHIAAETGAWAVFVQADHGDDPAVALYTGLGAREDVMHFDLPPRPRGA
>Mature_152_residues
MIVRRLGPGDIAAVRALNAVYGAAFDDPETYRADRPDDAWLARQLGREGVIVLVAELDGNIVGGLTAYELPKLEAARSEI
YLYDLAVDAAHRRCGIATALIGELQHIAAETGAWAVFVQADHGDDPAVALYTGLGAREDVMHFDLPPRPRGA

Specific function: Responsible for gentamicin resistance and has a limited substrate range [H]

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.60 [H]

Molecular weight: Translated: 16320; Mature: 16320

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRRLGPGDIAAVRALNAVYGAAFDDPETYRADRPDDAWLARQLGREGVIVLVAELDGN
CEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCC
IVGGLTAYELPKLEAARSEIYLYDLAVDAAHRRCGIATALIGELQHIAAETGAWAVFVQA
EECCCHHHCCCCCHHCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DHGDDPAVALYTGLGAREDVMHFDLPPRPRGA
CCCCCCEEEEEECCCCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MIVRRLGPGDIAAVRALNAVYGAAFDDPETYRADRPDDAWLARQLGREGVIVLVAELDGN
CEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEECCCC
IVGGLTAYELPKLEAARSEIYLYDLAVDAAHRRCGIATALIGELQHIAAETGAWAVFVQA
EECCCHHHCCCCCHHCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
DHGDDPAVALYTGLGAREDVMHFDLPPRPRGA
CCCCCCEEEEEECCCCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549372 [H]