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The map label for this gene is murA

Identifier: 103485992

GI number: 103485992

Start: 517129

End: 518412

Strand: Reverse

Name: murA

Synonym: Sala_0499

Alternate gene names: 103485992

Gene position: 518412-517129 (Counterclockwise)

Preceding gene: 103485993

Following gene: 103485987

Centisome position: 15.5

GC content: 68.77

Gene sequence:

>1284_bases
ATGGATCAAATCGTCATTCGCGGCGGCCAGCGACTCAAGGGCCGTATTCCCATCAGCGGTGCCAAGAACGCCGCGCTCAC
GCTGCTGCCGTGCGCGCTGCTCACCGACGAGCCGCTGACCTTGCGCAACCTGCCGCGGCTCGCCGACGTCGACGGGTTCG
GGCATTTGCTCAACCAGCTTGGTTGTTCGACGACGATCGAGGGATCGCGGCCCGAGGATTTCGGCCGCGTGATGACTGCG
CGCGCGACGACGCTGACCTCGACCGTCGCGCCCTATGACATTGTGCGCAAGATGCGCGCGTCGATCCTCGTGCTCGGCCC
GCTGCTCGCGCGCGCGGGCGAGGCGACGGTGTCGCTCCCCGGCGGCTGCGCGATCGGCAACCGCCCGATCGACCTGCACC
TGAAAGCGCTCGAAGCCTTTGGCGCCGAGATCGAACTGGCGTCGGGTTATGTGAAGGCGGTGGCGGCGGGCGGACGTCTT
GCGGGCGGCAGATTCACCTTCCCCGTCGTGTCGGTCGGCGCGACCGAAAATGCGGTGATGGCGGCGGTGCTCGCCAAGGG
CACGTGCGTGCTCGAAAATGCGGCGCGCGAGCCCGAGATCGTCGACCTGTGCAACTGCCTTGTCGCGATGGGCGCGCATA
TCGAGGGCATCGGCACCGAAACGCTGACGATCGAAGGCGTCGACCGCCTGCACGGCGCCACCTATCGCGTGATGGCCGAC
CGCATCGAGGCGGGAAGCTACGCCTGCGCCGCGGTGATTACCGAGGGCGACGTCGAACTGGTCGGCGCCAAGGCGAGCGA
GATGGAAGCGACGCTCGCCGCGCTGCGCGAAGCGGGCGCGACGGTCGAGGAGACAAAGGGCGGCATCCGCGTCGCCATGG
CGGGCCGCGCGCAGCCGGTGACGCTGAGCACCGCGCCCTACCCCGGCTTCGCCACCGACATGCAGGCGCAGTTCATGGCG
ATGGCGACGCTCGGCACCGGCGCGTCGCTGTTCACCGAAACGATCTTCGAGAACCGCTATATGCACGTTCCCGAGCTGGC
GCGCATGGGCTGCGACATCCAGGTCAAGGGCCGCACCGCGGTGGTGCGCGGGGTCGACCGGCTGATCGGCGCGCCGGTGA
TGGCGACCGACCTTCGCGCCTCGATGAGCCTGATCATCGCCGGACTCGCGGCCGAGGGCACAACCGAGGTGAACCGCGTC
TATCACCTCGACCGCGGTTACGAGCGGCTGGAGGAAAAGCTCCAGGCCGTGGGCGCCGACATCGAGCGGATCAGCGCGGG
GTAG

Upstream 100 bases:

>100_bases
GAGCCACTATGGCCACTTCCGGCCGAAACCGGACATCGCCTTGACCGCCCCGACCACCGCACCCGCTTGCACGCCCCCGT
GCATCCGCTAAAGACCGCGC

Downstream 100 bases:

>100_bases
GCGTCAGCGTCTCGGCGCGGCCGTAAGTGCCGCGCGCCTCGCCCTTCATCCAGTCGCCAAGCAGCTTCAGATAGCCGTCG
GTGATGCGCGTGTAGGACCG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MDQIVIRGGQRLKGRIPISGAKNAALTLLPCALLTDEPLTLRNLPRLADVDGFGHLLNQLGCSTTIEGSRPEDFGRVMTA
RATTLTSTVAPYDIVRKMRASILVLGPLLARAGEATVSLPGGCAIGNRPIDLHLKALEAFGAEIELASGYVKAVAAGGRL
AGGRFTFPVVSVGATENAVMAAVLAKGTCVLENAAREPEIVDLCNCLVAMGAHIEGIGTETLTIEGVDRLHGATYRVMAD
RIEAGSYACAAVITEGDVELVGAKASEMEATLAALREAGATVEETKGGIRVAMAGRAQPVTLSTAPYPGFATDMQAQFMA
MATLGTGASLFTETIFENRYMHVPELARMGCDIQVKGRTAVVRGVDRLIGAPVMATDLRASMSLIIAGLAAEGTTEVNRV
YHLDRGYERLEEKLQAVGADIERISAG

Sequences:

>Translated_427_residues
MDQIVIRGGQRLKGRIPISGAKNAALTLLPCALLTDEPLTLRNLPRLADVDGFGHLLNQLGCSTTIEGSRPEDFGRVMTA
RATTLTSTVAPYDIVRKMRASILVLGPLLARAGEATVSLPGGCAIGNRPIDLHLKALEAFGAEIELASGYVKAVAAGGRL
AGGRFTFPVVSVGATENAVMAAVLAKGTCVLENAAREPEIVDLCNCLVAMGAHIEGIGTETLTIEGVDRLHGATYRVMAD
RIEAGSYACAAVITEGDVELVGAKASEMEATLAALREAGATVEETKGGIRVAMAGRAQPVTLSTAPYPGFATDMQAQFMA
MATLGTGASLFTETIFENRYMHVPELARMGCDIQVKGRTAVVRGVDRLIGAPVMATDLRASMSLIIAGLAAEGTTEVNRV
YHLDRGYERLEEKLQAVGADIERISAG
>Mature_427_residues
MDQIVIRGGQRLKGRIPISGAKNAALTLLPCALLTDEPLTLRNLPRLADVDGFGHLLNQLGCSTTIEGSRPEDFGRVMTA
RATTLTSTVAPYDIVRKMRASILVLGPLLARAGEATVSLPGGCAIGNRPIDLHLKALEAFGAEIELASGYVKAVAAGGRL
AGGRFTFPVVSVGATENAVMAAVLAKGTCVLENAAREPEIVDLCNCLVAMGAHIEGIGTETLTIEGVDRLHGATYRVMAD
RIEAGSYACAAVITEGDVELVGAKASEMEATLAALREAGATVEETKGGIRVAMAGRAQPVTLSTAPYPGFATDMQAQFMA
MATLGTGASLFTETIFENRYMHVPELARMGCDIQVKGRTAVVRGVDRLIGAPVMATDLRASMSLIIAGLAAEGTTEVNRV
YHLDRGYERLEEKLQAVGADIERISAG

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=426, Percent_Identity=51.1737089201878, Blast_Score=419, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_SPHAL (Q1GVV2)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615553.1
- ProteinModelPortal:   Q1GVV2
- SMR:   Q1GVV2
- GeneID:   4081389
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0499
- NMPDR:   fig|317655.9.peg.457
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   SALA317655:SALA_0499-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44763; Mature: 44763

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: ACT_SITE 123-123

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQIVIRGGQRLKGRIPISGAKNAALTLLPCALLTDEPLTLRNLPRLADVDGFGHLLNQL
CCCEEEECCCEECCCCCCCCCCCCEEEEEEHHHHCCCCCHHHCCCCCCCCCHHHHHHHHH
GCSTTIEGSRPEDFGRVMTARATTLTSTVAPYDIVRKMRASILVLGPLLARAGEATVSLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GGCAIGNRPIDLHLKALEAFGAEIELASGYVKAVAAGGRLAGGRFTFPVVSVGATENAVM
CCCEECCCCCEEEHHHHHHCCCEEEECCCHHHHHHCCCEECCCEEEEEEEEECCCCHHHH
AAVLAKGTCVLENAAREPEIVDLCNCLVAMGAHIEGIGTETLTIEGVDRLHGATYRVMAD
HHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEECCHHHHCCCHHHHHHH
RIEAGSYACAAVITEGDVELVGAKASEMEATLAALREAGATVEETKGGIRVAMAGRAQPV
HHCCCCEEEEEEEECCCEEEEECCHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCCCE
TLSTAPYPGFATDMQAQFMAMATLGTGASLFTETIFENRYMHVPELARMGCDIQVKGRTA
EEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCCEEECCCHH
VVRGVDRLIGAPVMATDLRASMSLIIAGLAAEGTTEVNRVYHLDRGYERLEEKLQAVGAD
HHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHEEHHHHHHHHHHHHHHHCCC
IERISAG
HHHHCCC
>Mature Secondary Structure
MDQIVIRGGQRLKGRIPISGAKNAALTLLPCALLTDEPLTLRNLPRLADVDGFGHLLNQL
CCCEEEECCCEECCCCCCCCCCCCEEEEEEHHHHCCCCCHHHCCCCCCCCCHHHHHHHHH
GCSTTIEGSRPEDFGRVMTARATTLTSTVAPYDIVRKMRASILVLGPLLARAGEATVSLP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECC
GGCAIGNRPIDLHLKALEAFGAEIELASGYVKAVAAGGRLAGGRFTFPVVSVGATENAVM
CCCEECCCCCEEEHHHHHHCCCEEEECCCHHHHHHCCCEECCCEEEEEEEEECCCCHHHH
AAVLAKGTCVLENAAREPEIVDLCNCLVAMGAHIEGIGTETLTIEGVDRLHGATYRVMAD
HHHHHCCCEEECCCCCCCHHHHHHHHHHHHCCCEECCCCCEEEECCHHHHCCCHHHHHHH
RIEAGSYACAAVITEGDVELVGAKASEMEATLAALREAGATVEETKGGIRVAMAGRAQPV
HHCCCCEEEEEEEECCCEEEEECCHHHHHHHHHHHHHHCCCHHHCCCCEEEEECCCCCCE
TLSTAPYPGFATDMQAQFMAMATLGTGASLFTETIFENRYMHVPELARMGCDIQVKGRTA
EEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCCEEECCCHH
VVRGVDRLIGAPVMATDLRASMSLIIAGLAAEGTTEVNRVYHLDRGYERLEEKLQAVGAD
HHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCHHHHHHEEHHHHHHHHHHHHHHHCCC
IERISAG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA