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The map label for this gene is ydeP [H]

Identifier: 103485682

GI number: 103485682

Start: 195234

End: 197504

Strand: Direct

Name: ydeP [H]

Synonym: Sala_0186

Alternate gene names: 103485682

Gene position: 195234-197504 (Clockwise)

Preceding gene: 103485681

Following gene: 103485686

Centisome position: 5.84

GC content: 66.14

Gene sequence:

>2271_bases
ATGGCCGAGCACCGCCCCCGCTACAAACGCTACGATCGCCCCGCCGGCGGCTGGGGCGCTGCGGCGGCGACGGCAAAGGT
GCTGCTCGAACAGAGCGTCGTCACCAAGGGGTCGCGCGCGCTCCTGTCGATGAACCAGCCGGGCGGCTTCAAATGTCCCA
GTTGCGCCTTTCCCGACGCCGCCTGCACGAAGAAGCTCGAGTTCTGTGAAAATGGCGCCAAGGCGCTCGCGCACGAAGCG
ACCAAGTTTCGCGTCACGCGCGACTTTTTCGCGCAGCATAGCGTCACCGAGCTGATAGCGCAGTCGGACCATTGGCTCGA
AATGCAGGGCCGGTTGACCGAACCGATGCGCTACGACGCCGCGACCGACCATTATGTGCCGGTGGGTTGGGACGACGCCT
TCGCACTGATCGGCCGCCACCTTCGCGCGCTCGACAGCCCGCACCGCGCCGAGTTCTATACGTCGGGCCGCACGCCGAAC
GAGGCCGCCTTCCTCTATTCGATCTTCGTGCGCGAGTTTGGCACGAACAATTTTCCCGACTGTTCGAACATGTGCCACGA
ACCGACGAGCCGCGGCCTGCCGTCGTCGATCGGCATCGGCAAGGGCACGGTGATCCTCGAGGATTTCGACCATGCGGAAG
CAATTTTCCTCATCGGCCACAATGCCGGGACCAACGCGCCGCGGATGATGACCCCGCTCGTCGAGGCGCGCAAACGCGGG
GTGCCGATCGTCGCGGTCAACCCGATGCCCGAACGCGCGCTCATCCGCTTCACCGAGCCGCAGGATATCGTCCAGATGGC
GACCTTCGGCTCGACCGAGATCAGCAGCGAGTTCGTGCATATCAAGATCGGCGGCGACCTCGCGCTGCTCAAGGGCATGA
TGAAGGTGCTTTTCGAGCGCGACGCCGCGGGCGAGGCGGTGCTCGACCATGATTTCATCGCCGAACATACCGAAGGCCTC
GCGGCGCTGTGCGCCGATGTCGAGGCGCAATCGTGGGACGCGATCACCGCCGCTGCGGGGGTCGACGCGGCGCAGATCCG
CCGCTGCGCCGACATCTATATCCGCTCGAACGCGACGATCATCTGCTACGGCATGGGCGTGACCCAGCATCAGCGCGGGT
CCGAACTCGTCCAGCAGGTCGCGAACCTGCTGCTACTCCGCGGCAATTTCGGCAAGCCCGGCGCGGGCATCTCGCCGATC
CGTGGCCATTCGAACGTGCAGGGCGACCGCACCGTCGGCATCGACGAGCGGCCCGCGCCCGCCTATCTCGACCGTCTCCG
CGACGTCTTCGGCTTCGATCCGCCGCGCGAGCACGGGCATCACAGCGTCGAGGCGGTCGAGGCGATGCTCGCGGGCGAGG
CCAGGGTCTTCATCGGCCTCGGCGGCAATTTCGTTCGCGCGGTGCCGGATACGACCCGTGCCTGTGCCGCGATGCAGCGA
CTCGACCTCACTGTTGGCATCGCGACCAAGCTCAACCGCGGCCACCTCGTCCACGGCAAGGATGCGCTGATCCTGCCGGT
GATCGCGCGATCCGAACGGATCGAAACCGCGAGGGGCGAGCAGTTCGTGACGATCGAGGATTCGATGTCGAACGTCACCG
CCTCGCGCGGCGTGCTCGACCCAGCCAGTGAGCACCTGTTGTCAGAGGTCGAGATCGTCTGCCGCATGGCGATGGCGACG
CTGCCCGGCAGCAAGGTCGACTGGCGGCGCTATATCGACGATTATGACGCGATCCGCGACAAGATCGCCGCCGTCTATCC
CGCCATCTACGAAGGCTTTTCGCAGCGCATCCGGGCGCCGATGGGCTTTCACCTCGACATTCCGCCGCGCCGCCGCGTCT
GGCCGACGCCGACGGGCAAGGCCAATTTCCTTGTCCTGCCGGGGCTCGCGGTAAACGCGGCGGTCGACGATCCCGCCATG
CTGCGCCTCGCGACGGTGCGATCGCACGACCAGTTCAACACGACAATCTATAGCTACAACGACCGGTATCGCGGCATTTA
CGGCGACCGGATGGTGCTGTTCATGAACGCCGACGACAGGACAGACCGCGGGCTGGAGGCTGGCGCGCGCGTCGCGCTCG
AAACGATCGCCGACGACGGCACCGCGCGGCGCGTCGAGGGGTTGACGCTGATCGACTATCCGATGTCGCGCGGTTCGGTC
GCGGGCTATTATCCCGAACTCAACCCGCTGCTCCCGCTCGCCTTCCACGACCGGGTGAGCGGCTGCCCGGCGGCGAAAGC
GATCCCGGTGCGCGTTGTCGCAATGTCCTGA

Upstream 100 bases:

>100_bases
TCGCCGGAATGGCGAGATTATTGAGGCTGGTCGTTTGCAGTCGCGCACGCCGCACCAAAGAGCGGTGGCCAGCCGCCGGG
CGCTGTGCTTAGATGCGTCC

Downstream 100 bases:

>100_bases
GTCAGCTTTTCGCCAGCCGTTCGAGGTCGGCAAGGCTGTTGATATTGGGCGGCGCAAAATCGCACTGCACCGCGCGCGCG
GCGATGCGGCGGGCGAAAGC

Product: oxidoreductase alpha (molybdopterin) subunit

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MAEHRPRYKRYDRPAGGWGAAAATAKVLLEQSVVTKGSRALLSMNQPGGFKCPSCAFPDAACTKKLEFCENGAKALAHEA
TKFRVTRDFFAQHSVTELIAQSDHWLEMQGRLTEPMRYDAATDHYVPVGWDDAFALIGRHLRALDSPHRAEFYTSGRTPN
EAAFLYSIFVREFGTNNFPDCSNMCHEPTSRGLPSSIGIGKGTVILEDFDHAEAIFLIGHNAGTNAPRMMTPLVEARKRG
VPIVAVNPMPERALIRFTEPQDIVQMATFGSTEISSEFVHIKIGGDLALLKGMMKVLFERDAAGEAVLDHDFIAEHTEGL
AALCADVEAQSWDAITAAAGVDAAQIRRCADIYIRSNATIICYGMGVTQHQRGSELVQQVANLLLLRGNFGKPGAGISPI
RGHSNVQGDRTVGIDERPAPAYLDRLRDVFGFDPPREHGHHSVEAVEAMLAGEARVFIGLGGNFVRAVPDTTRACAAMQR
LDLTVGIATKLNRGHLVHGKDALILPVIARSERIETARGEQFVTIEDSMSNVTASRGVLDPASEHLLSEVEIVCRMAMAT
LPGSKVDWRRYIDDYDAIRDKIAAVYPAIYEGFSQRIRAPMGFHLDIPPRRRVWPTPTGKANFLVLPGLAVNAAVDDPAM
LRLATVRSHDQFNTTIYSYNDRYRGIYGDRMVLFMNADDRTDRGLEAGARVALETIADDGTARRVEGLTLIDYPMSRGSV
AGYYPELNPLLPLAFHDRVSGCPAAKAIPVRVVAMS

Sequences:

>Translated_756_residues
MAEHRPRYKRYDRPAGGWGAAAATAKVLLEQSVVTKGSRALLSMNQPGGFKCPSCAFPDAACTKKLEFCENGAKALAHEA
TKFRVTRDFFAQHSVTELIAQSDHWLEMQGRLTEPMRYDAATDHYVPVGWDDAFALIGRHLRALDSPHRAEFYTSGRTPN
EAAFLYSIFVREFGTNNFPDCSNMCHEPTSRGLPSSIGIGKGTVILEDFDHAEAIFLIGHNAGTNAPRMMTPLVEARKRG
VPIVAVNPMPERALIRFTEPQDIVQMATFGSTEISSEFVHIKIGGDLALLKGMMKVLFERDAAGEAVLDHDFIAEHTEGL
AALCADVEAQSWDAITAAAGVDAAQIRRCADIYIRSNATIICYGMGVTQHQRGSELVQQVANLLLLRGNFGKPGAGISPI
RGHSNVQGDRTVGIDERPAPAYLDRLRDVFGFDPPREHGHHSVEAVEAMLAGEARVFIGLGGNFVRAVPDTTRACAAMQR
LDLTVGIATKLNRGHLVHGKDALILPVIARSERIETARGEQFVTIEDSMSNVTASRGVLDPASEHLLSEVEIVCRMAMAT
LPGSKVDWRRYIDDYDAIRDKIAAVYPAIYEGFSQRIRAPMGFHLDIPPRRRVWPTPTGKANFLVLPGLAVNAAVDDPAM
LRLATVRSHDQFNTTIYSYNDRYRGIYGDRMVLFMNADDRTDRGLEAGARVALETIADDGTARRVEGLTLIDYPMSRGSV
AGYYPELNPLLPLAFHDRVSGCPAAKAIPVRVVAMS
>Mature_755_residues
AEHRPRYKRYDRPAGGWGAAAATAKVLLEQSVVTKGSRALLSMNQPGGFKCPSCAFPDAACTKKLEFCENGAKALAHEAT
KFRVTRDFFAQHSVTELIAQSDHWLEMQGRLTEPMRYDAATDHYVPVGWDDAFALIGRHLRALDSPHRAEFYTSGRTPNE
AAFLYSIFVREFGTNNFPDCSNMCHEPTSRGLPSSIGIGKGTVILEDFDHAEAIFLIGHNAGTNAPRMMTPLVEARKRGV
PIVAVNPMPERALIRFTEPQDIVQMATFGSTEISSEFVHIKIGGDLALLKGMMKVLFERDAAGEAVLDHDFIAEHTEGLA
ALCADVEAQSWDAITAAAGVDAAQIRRCADIYIRSNATIICYGMGVTQHQRGSELVQQVANLLLLRGNFGKPGAGISPIR
GHSNVQGDRTVGIDERPAPAYLDRLRDVFGFDPPREHGHHSVEAVEAMLAGEARVFIGLGGNFVRAVPDTTRACAAMQRL
DLTVGIATKLNRGHLVHGKDALILPVIARSERIETARGEQFVTIEDSMSNVTASRGVLDPASEHLLSEVEIVCRMAMATL
PGSKVDWRRYIDDYDAIRDKIAAVYPAIYEGFSQRIRAPMGFHLDIPPRRRVWPTPTGKANFLVLPGLAVNAAVDDPAML
RLATVRSHDQFNTTIYSYNDRYRGIYGDRMVLFMNADDRTDRGLEAGARVALETIADDGTARRVEGLTLIDYPMSRGSVA
GYYPELNPLLPLAFHDRVSGCPAAKAIPVRVVAMS

Specific function: Probably involved in acid resistance [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=755, Percent_Identity=48.6092715231788, Blast_Score=733, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=623, Percent_Identity=24.7191011235955, Blast_Score=152, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.2.1.2

Molecular weight: Translated: 82822; Mature: 82691

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00678 WD_REPEATS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHRPRYKRYDRPAGGWGAAAATAKVLLEQSVVTKGSRALLSMNQPGGFKCPSCAFPDA
CCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCH
ACTKKLEFCENGAKALAHEATKFRVTRDFFAQHSVTELIAQSDHWLEMQGRLTEPMRYDA
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
ATDHYVPVGWDDAFALIGRHLRALDSPHRAEFYTSGRTPNEAAFLYSIFVREFGTNNFPD
CCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
CSNMCHEPTSRGLPSSIGIGKGTVILEDFDHAEAIFLIGHNAGTNAPRMMTPLVEARKRG
HHHHHCCCHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
VPIVAVNPMPERALIRFTEPQDIVQMATFGSTEISSEFVHIKIGGDLALLKGMMKVLFER
CCEEEECCCCCCCEEEECCHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
DAAGEAVLDHDFIAEHTEGLAALCADVEAQSWDAITAAAGVDAAQIRRCADIYIRSNATI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHEEEECCCEE
ICYGMGVTQHQRGSELVQQVANLLLLRGNFGKPGAGISPIRGHSNVQGDRTVGIDERPAP
EEEECCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCH
AYLDRLRDVFGFDPPREHGHHSVEAVEAMLAGEARVFIGLGGNFVRAVPDTTRACAAMQR
HHHHHHHHHHCCCCCHHCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHH
LDLTVGIATKLNRGHLVHGKDALILPVIARSERIETARGEQFVTIEDSMSNVTASRGVLD
HCEEEEEEEECCCCCEEECCCCEEEEEECCCCHHHHCCCCEEEEEECCHHHHHHHCCCCC
PASEHLLSEVEIVCRMAMATLPGSKVDWRRYIDDYDAIRDKIAAVYPAIYEGFSQRIRAP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MGFHLDIPPRRRVWPTPTGKANFLVLPGLAVNAAVDDPAMLRLATVRSHDQFNTTIYSYN
CCEEECCCCCCCCCCCCCCCCCEEEECCEEEECCCCCHHHEEEEHHHCCCCCCCEEEEEC
DRYRGIYGDRMVLFMNADDRTDRGLEAGARVALETIADDGTARRVEGLTLIDYPMSRGSV
CCCCCEECCEEEEEECCCCCCCCCHHHHHHEEHHHHHCCCCCHHCCCEEEEECCCCCCCC
AGYYPELNPLLPLAFHDRVSGCPAAKAIPVRVVAMS
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
AEHRPRYKRYDRPAGGWGAAAATAKVLLEQSVVTKGSRALLSMNQPGGFKCPSCAFPDA
CCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCH
ACTKKLEFCENGAKALAHEATKFRVTRDFFAQHSVTELIAQSDHWLEMQGRLTEPMRYDA
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
ATDHYVPVGWDDAFALIGRHLRALDSPHRAEFYTSGRTPNEAAFLYSIFVREFGTNNFPD
CCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
CSNMCHEPTSRGLPSSIGIGKGTVILEDFDHAEAIFLIGHNAGTNAPRMMTPLVEARKRG
HHHHHCCCHHCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
VPIVAVNPMPERALIRFTEPQDIVQMATFGSTEISSEFVHIKIGGDLALLKGMMKVLFER
CCEEEECCCCCCCEEEECCHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
DAAGEAVLDHDFIAEHTEGLAALCADVEAQSWDAITAAAGVDAAQIRRCADIYIRSNATI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHEEEECCCEE
ICYGMGVTQHQRGSELVQQVANLLLLRGNFGKPGAGISPIRGHSNVQGDRTVGIDERPAP
EEEECCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCH
AYLDRLRDVFGFDPPREHGHHSVEAVEAMLAGEARVFIGLGGNFVRAVPDTTRACAAMQR
HHHHHHHHHHCCCCCHHCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCHHHHHHHHHH
LDLTVGIATKLNRGHLVHGKDALILPVIARSERIETARGEQFVTIEDSMSNVTASRGVLD
HCEEEEEEEECCCCCEEECCCCEEEEEECCCCHHHHCCCCEEEEEECCHHHHHHHCCCCC
PASEHLLSEVEIVCRMAMATLPGSKVDWRRYIDDYDAIRDKIAAVYPAIYEGFSQRIRAP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
MGFHLDIPPRRRVWPTPTGKANFLVLPGLAVNAAVDDPAMLRLATVRSHDQFNTTIYSYN
CCEEECCCCCCCCCCCCCCCCCEEEECCEEEECCCCCHHHEEEEHHHCCCCCCCEEEEEC
DRYRGIYGDRMVLFMNADDRTDRGLEAGARVALETIADDGTARRVEGLTLIDYPMSRGSV
CCCCCEECCEEEEEECCCCCCCCCHHHHHHEEHHHHHCCCCCHHCCCEEEEECCCCCCCC
AGYYPELNPLLPLAFHDRVSGCPAAKAIPVRVVAMS
EEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]