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The map label for this gene is rpiA

Identifier: 103485587

GI number: 103485587

Start: 93158

End: 93844

Strand: Direct

Name: rpiA

Synonym: Sala_0089

Alternate gene names: 103485587

Gene position: 93158-93844 (Clockwise)

Preceding gene: 103485583

Following gene: 103485588

Centisome position: 2.78

GC content: 60.12

Gene sequence:

>687_bases
ATGTCCAACTTCGTCGCTGAGAAATCGATCGCGGCGGTGAGAGCAGTCGATGAGGTTCGCGATGGCATGCTTGTCGGGTT
AGGGACCGGAAGCACCGCCGCTTATGCCGTGAAAAGCCTCAGCGAGCGCATCAAGCACGGCCTTCGCATCACCGCGGTCG
CCACATCCCAAGCGACCGAAGCTCTAGCTCTCCGTCTTGCGGTGCCGCTTGTTCCCTTTCAACAGCTTAGCGCTGTCGAC
CTGACGATCGACGGCGCCGATGAAATCGATGACCGCTTCCAAGCCATCAAAGGGGGAGGCGGCGCCCTGCTTCGCGAGAA
AATCACCGAGTCCGCATCCACGCGCGTGATCATCATCGCCGATTCCAGCAAGCTTGTTGCGCAGCTCGGCAAATTCCCTC
TGCCCGTGGAGGTGGTTCCTTTCGCCACCGAGTTTGTTCGTGCACGCCTGTCCGCACTCGGAGCCCGTGTTACTGTTCGC
GAAGCGGGTGGGACGCCCTTCCTCACGGACCAGGGCAATTACATCCTGGACGCAGCTTTGGATGAGATACCAAGGCCGCG
CGAGATCGCCGCCGCGATCACCACAATCCCGGGCGTCCTGGAGCATGGACTGTTCTTGGATGAAATCGATACAATCATGA
TTGCGCGCGGTGACATGGTGGAGGTGCGACACCGGGGTGAAGCTTGA

Upstream 100 bases:

>100_bases
TAACGGCCTACCGAGTTGGAAGCGTCAAACCTTGTTCGCGCGACTGCATTCCGCAGGTATTAAGGCTGGCCGCTCGGCCA
GAAAGGAGGGGTCTCGCTCC

Downstream 100 bases:

>100_bases
GGTCTTGCATATCATCACCTGCGCGGCGTCGATGGCGGCGCTGACACATTCTTAGCCGCGACCTCGGGCATTTTTTTAAC
CCGTTCGTCGCGCGCCATAG

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSNFVAEKSIAAVRAVDEVRDGMLVGLGTGSTAAYAVKSLSERIKHGLRITAVATSQATEALALRLAVPLVPFQQLSAVD
LTIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIADSSKLVAQLGKFPLPVEVVPFATEFVRARLSALGARVTVR
EAGGTPFLTDQGNYILDAALDEIPRPREIAAAITTIPGVLEHGLFLDEIDTIMIARGDMVEVRHRGEA

Sequences:

>Translated_228_residues
MSNFVAEKSIAAVRAVDEVRDGMLVGLGTGSTAAYAVKSLSERIKHGLRITAVATSQATEALALRLAVPLVPFQQLSAVD
LTIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIADSSKLVAQLGKFPLPVEVVPFATEFVRARLSALGARVTVR
EAGGTPFLTDQGNYILDAALDEIPRPREIAAAITTIPGVLEHGLFLDEIDTIMIARGDMVEVRHRGEA
>Mature_227_residues
SNFVAEKSIAAVRAVDEVRDGMLVGLGTGSTAAYAVKSLSERIKHGLRITAVATSQATEALALRLAVPLVPFQQLSAVDL
TIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIADSSKLVAQLGKFPLPVEVVPFATEFVRARLSALGARVTVRE
AGGTPFLTDQGNYILDAALDEIPRPREIAAAITTIPGVLEHGLFLDEIDTIMIARGDMVEVRHRGEA

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=228, Percent_Identity=36.8421052631579, Blast_Score=130, Evalue=9e-31,
Organism=Escherichia coli, GI1789280, Length=193, Percent_Identity=42.4870466321244, Blast_Score=131, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17551758, Length=223, Percent_Identity=33.6322869955157, Blast_Score=119, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6324669, Length=243, Percent_Identity=34.156378600823, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281364072, Length=198, Percent_Identity=36.3636363636364, Blast_Score=113, Evalue=8e-26,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_SPHAL (Q1GX07)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615148.1
- ProteinModelPortal:   Q1GX07
- SMR:   Q1GX07
- GeneID:   4082064
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0089
- NMPDR:   fig|317655.9.peg.82
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- BioCyc:   SALA317655:SALA_0089-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24200; Mature: 24069

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFVAEKSIAAVRAVDEVRDGMLVGLGTGSTAAYAVKSLSERIKHGLRITAVATSQATE
CCCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCHHHH
ALALRLAVPLVPFQQLSAVDLTIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIA
HHHHHHHCCCCCHHHCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEE
DSSKLVAQLGKFPLPVEVVPFATEFVRARLSALGARVTVREAGGTPFLTDQGNYILDAAL
CCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCEEEEEHH
DEIPRPREIAAAITTIPGVLEHGLFLDEIDTIMIARGDMVEVRHRGEA
HHCCCCHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCEEEECCCCCC
>Mature Secondary Structure 
SNFVAEKSIAAVRAVDEVRDGMLVGLGTGSTAAYAVKSLSERIKHGLRITAVATSQATE
CCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEECCHHHH
ALALRLAVPLVPFQQLSAVDLTIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIA
HHHHHHHCCCCCHHHCCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEE
DSSKLVAQLGKFPLPVEVVPFATEFVRARLSALGARVTVREAGGTPFLTDQGNYILDAAL
CCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCEEEEEHH
DEIPRPREIAAAITTIPGVLEHGLFLDEIDTIMIARGDMVEVRHRGEA
HHCCCCHHHHHHHHHHHHHHHHCCCHHHHCEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA