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The map label for this gene is arsR [H]

Identifier: 103485532

GI number: 103485532

Start: 32993

End: 33979

Strand: Direct

Name: arsR [H]

Synonym: Sala_0034

Alternate gene names: 103485532

Gene position: 32993-33979 (Clockwise)

Preceding gene: 103485528

Following gene: 103485533

Centisome position: 0.99

GC content: 66.46

Gene sequence:

>987_bases
ATGAGCGAGCTGATCGACATTTGCCGGGCCTTGGCCGATCCGACCCGCTTGCGAGTCGTGGCCTTGCTGCGCGAGATGGA
ACTGGCGATCGGCGAGTTGGCGGTGGTTCTGGACCAGAGCCAGCCGCGTGTTTCCCGCCACGTCCGCATCCTGGTCGAAG
CGGGGATCGTCGAGCGGCGCCGTGAGGGAAGCTGGGTATTCCTGCGCATCGTCGCGGATGGGCCGATCGCCGCAATCATC
GCGCAAGCGGACAAATGGCCTTTTTCTGCGCGCGAAATGCGCGTGATCGCGCATGATGCGCGTCGCCTTGCGGCGGTGCG
CGCCGAACGCGCGGCAGCGGCCGCGCGATATTTCGCCGAACATGCTGCCGAATGGGATGCCATTCGCTCACGCCATGTCG
CCGAAAGCGAGGTCGAAGCGGCGATGCTGGCGATGATGCACAACCGCCGCCTTGGCCACCTTCTCGACATCGGGACGGGA
ACCGGGCGGATGGCAGAGATTTTTGCTCCGACCGCGCGCCGCATCACCGCCCTCGACCGCAGCCCCGAAATGCTGCGGAT
CGCCCGCGCCAAGCTCGAAAGACAGCCGGTGCCCGTCGACCTGATCCAGGGCGATTTTCTGGAGTTGCCGGTGGGGGACG
CGAGCGTCGACAGCATCGTCATTCATCAGGCGCTGCATTTTGCGCACGAACCCGATCGCGTGATCGCGGAAGCGAGCCGG
GTGCTGCGCGGCGGCGGCCACCTGCTGATCGTCGATTTCGCGCCGCACGAGGATGAGGAATTGCGCACGCTTGCCGCGCA
CGCCCGCCTCGGCTTTTCGGACGCGCAGATCCGCGGCTGGTTCGCCTCGGCGGGCCTGCTGCTCGAAACCACACAGACGC
TCGAAGGCGGGAAGCTGGCCGTCAAGCTCTGGCTCGGACGTCGCCGGAGCGACCAGGATCAACCCCCCGTCAGCGACGGC
GGACCGACGAAAAGGCTTGCTGCATGA

Upstream 100 bases:

>100_bases
GCCTTTCATCGCAATCGGTCGATGGTCTGCGCGCGCAGCGCGGAAATCGCGGGATGAGACTTGGTTGACCAGATATAAAG
AAAGCTTTATATGATGATTG

Downstream 100 bases:

>100_bases
CCGCGAATCTCGACGCGCTGGCGGAAGCGCGCCGCGCGGCGGCGTCGCCGTTGTTCGCCAATCTCGACGGCGACGTCGGC
GTCAGCTTCGAGTTTTTCCC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSELIDICRALADPTRLRVVALLREMELAIGELAVVLDQSQPRVSRHVRILVEAGIVERRREGSWVFLRIVADGPIAAII
AQADKWPFSAREMRVIAHDARRLAAVRAERAAAAARYFAEHAAEWDAIRSRHVAESEVEAAMLAMMHNRRLGHLLDIGTG
TGRMAEIFAPTARRITALDRSPEMLRIARAKLERQPVPVDLIQGDFLELPVGDASVDSIVIHQALHFAHEPDRVIAEASR
VLRGGGHLLIVDFAPHEDEELRTLAAHARLGFSDAQIRGWFASAGLLLETTQTLEGGKLAVKLWLGRRRSDQDQPPVSDG
GPTKRLAA

Sequences:

>Translated_328_residues
MSELIDICRALADPTRLRVVALLREMELAIGELAVVLDQSQPRVSRHVRILVEAGIVERRREGSWVFLRIVADGPIAAII
AQADKWPFSAREMRVIAHDARRLAAVRAERAAAAARYFAEHAAEWDAIRSRHVAESEVEAAMLAMMHNRRLGHLLDIGTG
TGRMAEIFAPTARRITALDRSPEMLRIARAKLERQPVPVDLIQGDFLELPVGDASVDSIVIHQALHFAHEPDRVIAEASR
VLRGGGHLLIVDFAPHEDEELRTLAAHARLGFSDAQIRGWFASAGLLLETTQTLEGGKLAVKLWLGRRRSDQDQPPVSDG
GPTKRLAA
>Mature_327_residues
SELIDICRALADPTRLRVVALLREMELAIGELAVVLDQSQPRVSRHVRILVEAGIVERRREGSWVFLRIVADGPIAAIIA
QADKWPFSAREMRVIAHDARRLAAVRAERAAAAARYFAEHAAEWDAIRSRHVAESEVEAAMLAMMHNRRLGHLLDIGTGT
GRMAEIFAPTARRITALDRSPEMLRIARAKLERQPVPVDLIQGDFLELPVGDASVDSIVIHQALHFAHEPDRVIAEASRV
LRGGGHLLIVDFAPHEDEELRTLAAHARLGFSDAQIRGWFASAGLLLETTQTLEGGKLAVKLWLGRRRSDQDQPPVSDGG
PTKRLAA

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=99, Percent_Identity=36.3636363636364, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 36222; Mature: 36091

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELIDICRALADPTRLRVVALLREMELAIGELAVVLDQSQPRVSRHVRILVEAGIVERR
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHEEHHHHHHHC
REGSWVFLRIVADGPIAAIIAQADKWPFSAREMRVIAHDARRLAAVRAERAAAAARYFAE
CCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAAEWDAIRSRHVAESEVEAAMLAMMHNRRLGHLLDIGTGTGRMAEIFAPTARRITALDR
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHCCHHHHHHHCCC
SPEMLRIARAKLERQPVPVDLIQGDFLELPVGDASVDSIVIHQALHFAHEPDRVIAEASR
CHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
VLRGGGHLLIVDFAPHEDEELRTLAAHARLGFSDAQIRGWFASAGLLLETTQTLEGGKLA
HHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHEEHHHHCCEEEEECCCCCCCEEE
VKLWLGRRRSDQDQPPVSDGGPTKRLAA
EEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SELIDICRALADPTRLRVVALLREMELAIGELAVVLDQSQPRVSRHVRILVEAGIVERR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHEEHHHHHHHC
REGSWVFLRIVADGPIAAIIAQADKWPFSAREMRVIAHDARRLAAVRAERAAAAARYFAE
CCCCEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAAEWDAIRSRHVAESEVEAAMLAMMHNRRLGHLLDIGTGTGRMAEIFAPTARRITALDR
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHCCHHHHHHHCCC
SPEMLRIARAKLERQPVPVDLIQGDFLELPVGDASVDSIVIHQALHFAHEPDRVIAEASR
CHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
VLRGGGHLLIVDFAPHEDEELRTLAAHARLGFSDAQIRGWFASAGLLLETTQTLEGGKLA
HHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHEEHHHHCCEEEEECCCCCCCEEE
VKLWLGRRRSDQDQPPVSDGGPTKRLAA
EEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]