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The map label for this gene is dnaA

Identifier: 103485499

GI number: 103485499

Start: 173

End: 1534

Strand: Direct

Name: dnaA

Synonym: Sala_0001

Alternate gene names: 103485499

Gene position: 173-1534 (Clockwise)

Preceding gene: NA

Following gene: 103485505

Centisome position: 0.01

GC content: 67.99

Gene sequence:

>1362_bases
GTGAGCGGTGATGCCGCAGCGCTCTGGCCGCGCGTCGCCGAGGGCCTGCGCCGCGACCTTGGCGCCCGCACCTTCGATCA
TTGGCTCAAGCCCGTGCGCTTCGCCGACTATTGCGCGCTGTCGGGCGTGGTGACGCTGGAGACCGCGAGCCGTTTTTCGG
CGAACTGGATCAACGAACGCTTCGGTGACCGGCTCGAACTCGCGTGGCGGCAGCAATTGCCTGCGGTACGCAGCGTCAGC
GTGCGCGGCGGCGTGGCGGCGACCGAGCGCGCCGCAACGCTGGCCTCGGTGCCACTTCCCACGTTCGACGCGCCGGCCGC
TCCCGCGGCCAACCCCGCGCTGCTCGGTTTCGACCCGCGGCTGTCGTTCGACCGCTTTGTCGTCGCGCGCTCGAACATCC
TCGCCGCCAACGCCGCGCGCCGGATGGCGATGGTCGAGCGGCCGCAGTTCAACCCGCTCTATCTCTGTTCGGGCACCGGG
CAGGGCAAGACGCATCTCCTGCAAGCGATCGCGCAGGATTATGCCGCCGCACACCCGACCGCGACGATCATCCTGATGTC
GGCGGAAAAGTTCATGCTCGAATTCGTCGGCGCGATGCGCGGCGGCGACATGATGGCGTTCAAGGCGCGGCTGCGCGCCG
CCGATCTGTTGCTGCTCGACGATCTGCAATTCGTTATCGGCAAGAATTCGACGCAGGAGGAACTGCTCCACACGATCGAC
GACCTGATGACGGCGGGCAAGCGCCTTGTCGTCACCGCCGACCGTCCGCCTGCGATGCTCGACGGGGTCGAGGCGCGGCT
CTTGTCGCGCCTGTCGGGCGGGCTCGTCGCCGATATCGAGGCGCCCGAGGATGATTTGCGCGAACGCATCATCCGCCAGC
GGCTCGCCGCGATGCCGATGGTCGAGGTGCCCGACGATGTCATCGCCTGGCTGGTCAAGCATTTCACGCGCAATATCCGC
GAGCTCGAGGGCGCGCTCAACAAGCTGCTCGCTTATGCCGCGCTCACCGGCGCGCGCATCGACCTCATGCTCGCCGAAGA
CCGGCTTGCCGAAAATGTCCGCTCGGCGCGCCCGCGCATCACGATCGACGAGATCCAGCGCGCGGTGTGCGCGCACTACC
GGCTCGACAGATCGGACATGAGCTCGAAGCGCCGCGTCCGCGCGGTCGCCCGCCCGCGTCAGGTCGCCATGTATCTGGCG
AAGGAACTCACGCCGCGCTCCTATCCCGAAATCGGGCGCCGTTTCGGTGGCCGCGACCATTCGACGGTGATCCACGCCGT
GCGCACGGTCGAGGCGTTGCGCGTCGCCGACAGCGAACTCGACGCCGAAATCGCCGCGATCCGGCGCAGTCTCAACAGCT
GA

Upstream 100 bases:

>100_bases
GTGGCGGCTGCCCGATACGTCGGCGCGCGGGGATTACAGGGGGCGGCACGGCGTGACAGAGAGCGGCAATCGGCATGGGC
AGAATGCAAGGGACGGAGCA

Downstream 100 bases:

>100_bases
TCCACAGGTCCGTCCCGAGGGTTATCCACGGGACTATCCACAGCGCGCGGCGGTCATGCGGGCAGTCATCGTCCAGCCTT
GTCATCCCGGATCAAGTCCG

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSGDAAALWPRVAEGLRRDLGARTFDHWLKPVRFADYCALSGVVTLETASRFSANWINERFGDRLELAWRQQLPAVRSVS
VRGGVAATERAATLASVPLPTFDAPAAPAANPALLGFDPRLSFDRFVVARSNILAANAARRMAMVERPQFNPLYLCSGTG
QGKTHLLQAIAQDYAAAHPTATIILMSAEKFMLEFVGAMRGGDMMAFKARLRAADLLLLDDLQFVIGKNSTQEELLHTID
DLMTAGKRLVVTADRPPAMLDGVEARLLSRLSGGLVADIEAPEDDLRERIIRQRLAAMPMVEVPDDVIAWLVKHFTRNIR
ELEGALNKLLAYAALTGARIDLMLAEDRLAENVRSARPRITIDEIQRAVCAHYRLDRSDMSSKRRVRAVARPRQVAMYLA
KELTPRSYPEIGRRFGGRDHSTVIHAVRTVEALRVADSELDAEIAAIRRSLNS

Sequences:

>Translated_453_residues
MSGDAAALWPRVAEGLRRDLGARTFDHWLKPVRFADYCALSGVVTLETASRFSANWINERFGDRLELAWRQQLPAVRSVS
VRGGVAATERAATLASVPLPTFDAPAAPAANPALLGFDPRLSFDRFVVARSNILAANAARRMAMVERPQFNPLYLCSGTG
QGKTHLLQAIAQDYAAAHPTATIILMSAEKFMLEFVGAMRGGDMMAFKARLRAADLLLLDDLQFVIGKNSTQEELLHTID
DLMTAGKRLVVTADRPPAMLDGVEARLLSRLSGGLVADIEAPEDDLRERIIRQRLAAMPMVEVPDDVIAWLVKHFTRNIR
ELEGALNKLLAYAALTGARIDLMLAEDRLAENVRSARPRITIDEIQRAVCAHYRLDRSDMSSKRRVRAVARPRQVAMYLA
KELTPRSYPEIGRRFGGRDHSTVIHAVRTVEALRVADSELDAEIAAIRRSLNS
>Mature_452_residues
SGDAAALWPRVAEGLRRDLGARTFDHWLKPVRFADYCALSGVVTLETASRFSANWINERFGDRLELAWRQQLPAVRSVSV
RGGVAATERAATLASVPLPTFDAPAAPAANPALLGFDPRLSFDRFVVARSNILAANAARRMAMVERPQFNPLYLCSGTGQ
GKTHLLQAIAQDYAAAHPTATIILMSAEKFMLEFVGAMRGGDMMAFKARLRAADLLLLDDLQFVIGKNSTQEELLHTIDD
LMTAGKRLVVTADRPPAMLDGVEARLLSRLSGGLVADIEAPEDDLRERIIRQRLAAMPMVEVPDDVIAWLVKHFTRNIRE
LEGALNKLLAYAALTGARIDLMLAEDRLAENVRSARPRITIDEIQRAVCAHYRLDRSDMSSKRRVRAVARPRQVAMYLAK
ELTPRSYPEIGRRFGGRDHSTVIHAVRTVEALRVADSELDAEIAAIRRSLNS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family

Homologues:

Organism=Escherichia coli, GI2367267, Length=469, Percent_Identity=34.9680170575693, Blast_Score=274, Evalue=8e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAA_SPHAL (Q1GN68)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_615060.1
- ProteinModelPortal:   Q1GN68
- SMR:   Q1GN68
- GeneID:   4082956
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_0001
- NMPDR:   fig|317655.9.peg.1
- HOGENOM:   HBG695666
- OMA:   CHTLNAL
- ProtClustDB:   PRK00149
- BioCyc:   SALA317655:SALA_0001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00377
- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1750.10
- PRINTS:   PR00051
- SMART:   SM00382
- SMART:   SM00760
- TIGRFAMs:   TIGR00362

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 50094; Mature: 49963

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDAAALWPRVAEGLRRDLGARTFDHWLKPVRFADYCALSGVVTLETASRFSANWINER
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHH
FGDRLELAWRQQLPAVRSVSVRGGVAATERAATLASVPLPTFDAPAAPAANPALLGFDPR
CCCHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCC
LSFDRFVVARSNILAANAARRMAMVERPQFNPLYLCSGTGQGKTHLLQAIAQDYAAAHPT
CCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
ATIILMSAEKFMLEFVGAMRGGDMMAFKARLRAADLLLLDDLQFVIGKNSTQEELLHTID
EEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DLMTAGKRLVVTADRPPAMLDGVEARLLSRLSGGLVADIEAPEDDLRERIIRQRLAAMPM
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCC
VEVPDDVIAWLVKHFTRNIRELEGALNKLLAYAALTGARIDLMLAEDRLAENVRSARPRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCC
TIDEIQRAVCAHYRLDRSDMSSKRRVRAVARPRQVAMYLAKELTPRSYPEIGRRFGGRDH
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCH
STVIHAVRTVEALRVADSELDAEIAAIRRSLNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGDAAALWPRVAEGLRRDLGARTFDHWLKPVRFADYCALSGVVTLETASRFSANWINER
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHH
FGDRLELAWRQQLPAVRSVSVRGGVAATERAATLASVPLPTFDAPAAPAANPALLGFDPR
CCCHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCC
LSFDRFVVARSNILAANAARRMAMVERPQFNPLYLCSGTGQGKTHLLQAIAQDYAAAHPT
CCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
ATIILMSAEKFMLEFVGAMRGGDMMAFKARLRAADLLLLDDLQFVIGKNSTQEELLHTID
EEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
DLMTAGKRLVVTADRPPAMLDGVEARLLSRLSGGLVADIEAPEDDLRERIIRQRLAAMPM
HHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCCC
VEVPDDVIAWLVKHFTRNIRELEGALNKLLAYAALTGARIDLMLAEDRLAENVRSARPRI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCC
TIDEIQRAVCAHYRLDRSDMSSKRRVRAVARPRQVAMYLAKELTPRSYPEIGRRFGGRDH
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCH
STVIHAVRTVEALRVADSELDAEIAAIRRSLNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA