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The map label for this gene is ygjG [C]

Identifier: 99082826

GI number: 99082826

Start: 3150350

End: 3151747

Strand: Direct

Name: ygjG [C]

Synonym: TM1040_2986

Alternate gene names: 99082826

Gene position: 3150350-3151747 (Clockwise)

Preceding gene: 99082825

Following gene: 99082827

Centisome position: 98.42

GC content: 58.15

Gene sequence:

>1398_bases
ATGACGACGATTACCAACCATCTGCCAACCGCAGAACTGCAGGCGCTGGATGCGGCGCATCATATGCATCCTTTCACCGC
TAATGGCGGATTGGCGCAGAAAGGTGCGCGTATCATCACGCGTGCCAAAGGCGTCACACTGACCGACAGCGAAGGTCATG
AGATCCTCGACGCGATGGCGGGGCTTTGGTGTGTCAACATCGGCTATGGTCGCGATGAACTGGCAGAGGTCGCGGCGCGC
CAAATGCGCGAGCTGCCCTACTACAATACGTTTTTCCAAACGACCCATGTACCGGTCATTGCGCTTGCGGCGAAGATTGC
CGAATTGGCGCCCGACAACCTGAACAATGTGTTCTTTGCAGGCTCGGGCTCTGAGGCCAACGACACCAACATCCGGATGG
TGCGCCATTACTGGGCGATGAAGGGTAAACCGACCAAATCCGTGATCATCTCGCGCAAGAACGCGTATCATGGCTCTTCT
GTCGGGTCCGGCTCGCTGGGTGGTATGTCTGCAATGCATGCACAGGGTGGTTTGCCGATTCCGGATATTCACCACATCAA
CCAGCCGAACTGGTGGGCAGAGGGCGGCAACACCGATCCCGAAGACTTTGGGCTTCAGCGCGCTCAGGAACTGGAAAAGG
CGATTCTCGAACTCGGCGAAGATCGCGTCGCCGCCTTTATTGCCGAACCGGTTCAAGGTGCCGGTGGCGTCATCGTTCCG
CCTGCGAGCTATTGGCCGGAAATTCAGCGTATCTGCGACAAGTACGAGATCCTGCTGATCGCGGATGAGGTGATCTGCGG
GTTTGGGCGCACGGGTAACTGGTTCGGGTCTGAAACCATGGGCATTCGTCCCGACATCATGACCATCGCCAAGGGGCTGT
CCTCGGGCTATGCGCCGATTGGTGGCTCGATTGTCTCGGATGAAGTCGCCGCAGTGATCGCGCAGGATGAATTCAACCAT
GGCTACACCTACTCCGGGCACCCGGTTGCTGCCGCGGTGGCGCTGGAGAACCTGCGCATTCTCGAAGAGGAAAACGTGCT
CGATCATGTCCGCAACGTGGCCGCACCCTATCTCAAAGAGAAGTGGGAAGCCCTGACTGCGCACCCTCTGGTGGGGGAAG
CGAAGATTGTCGGAATGATGGGGTCGATCGCTCTGACGCCTAACAAGGCGACTCGCGCAGCCTTTGAGGCTGAGGCGGGA
ACCGTTGGTTTCATCTGCCGCGAGCGTTGCTTTGCCAACAATCTGGTAATGCGTCACGTCGGCGACCGTATGATCATCTC
TCCGCCACTGGTGATCACCCCGGAGGAGATCGACACGCTGATCGCGCGTGCGACCAAATCCTTGGACGAATGCTACACCG
AATTGCAGGCACAAGGGCTGTTGAAATCGGCGGCTTAA

Upstream 100 bases:

>100_bases
GGAGCAGGTTCGGGCGGGGCTCACCCCGATCAACTGATTCGATTGACAGGCGATTTTTTGATCATATTCTGAGCGAAAGA
TTTCCGTTCAGGAGTGACTC

Downstream 100 bases:

>100_bases
GGGCTCCGGCGGTGATTCGAATTGATCAAAAGGGGCCGGAAACGGCCCTTTTTTTAAGCATTTCCCAAAAAAATCCCAGA
AGAGCGGTTGTGCTCACCGG

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTTITNHLPTAELQALDAAHHMHPFTANGGLAQKGARIITRAKGVTLTDSEGHEILDAMAGLWCVNIGYGRDELAEVAAR
QMRELPYYNTFFQTTHVPVIALAAKIAELAPDNLNNVFFAGSGSEANDTNIRMVRHYWAMKGKPTKSVIISRKNAYHGSS
VGSGSLGGMSAMHAQGGLPIPDIHHINQPNWWAEGGNTDPEDFGLQRAQELEKAILELGEDRVAAFIAEPVQGAGGVIVP
PASYWPEIQRICDKYEILLIADEVICGFGRTGNWFGSETMGIRPDIMTIAKGLSSGYAPIGGSIVSDEVAAVIAQDEFNH
GYTYSGHPVAAAVALENLRILEEENVLDHVRNVAAPYLKEKWEALTAHPLVGEAKIVGMMGSIALTPNKATRAAFEAEAG
TVGFICRERCFANNLVMRHVGDRMIISPPLVITPEEIDTLIARATKSLDECYTELQAQGLLKSAA

Sequences:

>Translated_465_residues
MTTITNHLPTAELQALDAAHHMHPFTANGGLAQKGARIITRAKGVTLTDSEGHEILDAMAGLWCVNIGYGRDELAEVAAR
QMRELPYYNTFFQTTHVPVIALAAKIAELAPDNLNNVFFAGSGSEANDTNIRMVRHYWAMKGKPTKSVIISRKNAYHGSS
VGSGSLGGMSAMHAQGGLPIPDIHHINQPNWWAEGGNTDPEDFGLQRAQELEKAILELGEDRVAAFIAEPVQGAGGVIVP
PASYWPEIQRICDKYEILLIADEVICGFGRTGNWFGSETMGIRPDIMTIAKGLSSGYAPIGGSIVSDEVAAVIAQDEFNH
GYTYSGHPVAAAVALENLRILEEENVLDHVRNVAAPYLKEKWEALTAHPLVGEAKIVGMMGSIALTPNKATRAAFEAEAG
TVGFICRERCFANNLVMRHVGDRMIISPPLVITPEEIDTLIARATKSLDECYTELQAQGLLKSAA
>Mature_464_residues
TTITNHLPTAELQALDAAHHMHPFTANGGLAQKGARIITRAKGVTLTDSEGHEILDAMAGLWCVNIGYGRDELAEVAARQ
MRELPYYNTFFQTTHVPVIALAAKIAELAPDNLNNVFFAGSGSEANDTNIRMVRHYWAMKGKPTKSVIISRKNAYHGSSV
GSGSLGGMSAMHAQGGLPIPDIHHINQPNWWAEGGNTDPEDFGLQRAQELEKAILELGEDRVAAFIAEPVQGAGGVIVPP
ASYWPEIQRICDKYEILLIADEVICGFGRTGNWFGSETMGIRPDIMTIAKGLSSGYAPIGGSIVSDEVAAVIAQDEFNHG
YTYSGHPVAAAVALENLRILEEENVLDHVRNVAAPYLKEKWEALTAHPLVGEAKIVGMMGSIALTPNKATRAAFEAEAGT
VGFICRERCFANNLVMRHVGDRMIISPPLVITPEEIDTLIARATKSLDECYTELQAQGLLKSAA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=28.0952380952381, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=28.3333333333333, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=26.046511627907, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442709, Length=377, Percent_Identity=28.1167108753316, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI13994255, Length=414, Percent_Identity=29.2270531400966, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI4557809, Length=438, Percent_Identity=25.7990867579909, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI284507298, Length=239, Percent_Identity=31.3807531380753, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI145693181, Length=405, Percent_Identity=30.6172839506173, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1786991, Length=451, Percent_Identity=28.8248337028825, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=27.8325123152709, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1788044, Length=407, Percent_Identity=28.2555282555283, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789016, Length=440, Percent_Identity=27.9545454545455, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787560, Length=343, Percent_Identity=30.0291545189504, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1786349, Length=356, Percent_Identity=25.561797752809, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32564660, Length=450, Percent_Identity=27.3333333333333, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=408, Percent_Identity=27.4509803921569, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71992977, Length=369, Percent_Identity=26.5582655826558, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=268, Percent_Identity=30.5970149253731, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324386, Length=472, Percent_Identity=27.5423728813559, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323470, Length=458, Percent_Identity=26.6375545851528, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324432, Length=339, Percent_Identity=27.7286135693215, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321456, Length=360, Percent_Identity=23.8888888888889, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=28.0459770114943, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI161085790, Length=433, Percent_Identity=27.4826789838337, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356575, Length=363, Percent_Identity=30.3030303030303, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI21357415, Length=424, Percent_Identity=24.5283018867925, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281366494, Length=359, Percent_Identity=24.2339832869081, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667139, Length=359, Percent_Identity=24.2339832869081, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24667143, Length=359, Percent_Identity=24.2339832869081, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50203; Mature: 50072

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTITNHLPTAELQALDAAHHMHPFTANGGLAQKGARIITRAKGVTLTDSEGHEILDAMA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHCCCCEEECCCCHHHHHHHH
GLWCVNIGYGRDELAEVAARQMRELPYYNTFFQTTHVPVIALAAKIAELAPDNLNNVFFA
HHEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEE
GSGSEANDTNIRMVRHYWAMKGKPTKSVIISRKNAYHGSSVGSGSLGGMSAMHAQGGLPI
CCCCCCCCCHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCC
PDIHHINQPNWWAEGGNTDPEDFGLQRAQELEKAILELGEDRVAAFIAEPVQGAGGVIVP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEC
PASYWPEIQRICDKYEILLIADEVICGFGRTGNWFGSETMGIRPDIMTIAKGLSSGYAPI
CHHHHHHHHHHHCHHEEEEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
GGSIVSDEVAAVIAQDEFNHGYTYSGHPVAAAVALENLRILEEENVLDHVRNVAAPYLKE
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWEALTAHPLVGEAKIVGMMGSIALTPNKATRAAFEAEAGTVGFICRERCFANNLVMRHV
HHHHHHCCCCCCCHHEEEEECCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
GDRMIISPPLVITPEEIDTLIARATKSLDECYTELQAQGLLKSAA
CCCEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTITNHLPTAELQALDAAHHMHPFTANGGLAQKGARIITRAKGVTLTDSEGHEILDAMA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHCCCCEEECCCCHHHHHHHH
GLWCVNIGYGRDELAEVAARQMRELPYYNTFFQTTHVPVIALAAKIAELAPDNLNNVFFA
HHEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEE
GSGSEANDTNIRMVRHYWAMKGKPTKSVIISRKNAYHGSSVGSGSLGGMSAMHAQGGLPI
CCCCCCCCCHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCCCCHHHHCCCCCCC
PDIHHINQPNWWAEGGNTDPEDFGLQRAQELEKAILELGEDRVAAFIAEPVQGAGGVIVP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEC
PASYWPEIQRICDKYEILLIADEVICGFGRTGNWFGSETMGIRPDIMTIAKGLSSGYAPI
CHHHHHHHHHHHCHHEEEEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
GGSIVSDEVAAVIAQDEFNHGYTYSGHPVAAAVALENLRILEEENVLDHVRNVAAPYLKE
CCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KWEALTAHPLVGEAKIVGMMGSIALTPNKATRAAFEAEAGTVGFICRERCFANNLVMRHV
HHHHHHCCCCCCCHHEEEEECCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
GDRMIISPPLVITPEEIDTLIARATKSLDECYTELQAQGLLKSAA
CCCEEECCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]