Click here to switch to the map view.

The map label for this gene is msrB [H]

Identifier: 99082643

GI number: 99082643

Start: 2965204

End: 2965653

Strand: Direct

Name: msrB [H]

Synonym: TM1040_2803

Alternate gene names: 99082643

Gene position: 2965204-2965653 (Clockwise)

Preceding gene: 99082642

Following gene: 99082644

Centisome position: 92.64

GC content: 57.33

Gene sequence:

>450_bases
ATGACCAAGTATTTCAAGAACCCCGACGCCATCGCTGCGCTGTCAGAAGAAGAATTCTACGTCACACAGAATTCTGGCAC
CGAACGTCCCGGCACCGGCAAGCTCCTGTCCAACAAGGAGCCCGGCATCTATGTGGACATCGTATCGGGCGAGCCGCTGT
TTGCCTCTTCCGACAAATATGAATCAGGCTGTGGCTGGCCAAGCTTCACCAAGCCGATCGAACCCGCACATGTGCAGGAA
CTCGAAGATCGCACCCTCGGCATGATCCGTACCGAGGTGCGCTCTACCCATGGCGACAGCCACCTCGGCCATGTCTTTCC
CGACGGCCCTGCTGATCGCGGCGGTCTGAGATATTGCATCAACTCGGCGTCCTTGCGCTTTATTCACCTCGACGACATGG
AGGCTGAAGGCTATGGCGCCTACATCAACCAAGTGGAGGACCACCGATGA

Upstream 100 bases:

>100_bases
CGCATCTCAAGCACAAGAGAGCCAACAGGGATGGATTGGGGTTTGAAAACGCGCCCGCCAACCCCAGCTATAGACGCATC
CAATCAGGTGGGAGGGCCCC

Downstream 100 bases:

>100_bases
CCACAACTGAACGCGCCGTTCTGGCAGGCGGCTGCTTCTGGGGCATGCAGGAGCTAATCCGTCATCGCAAGGGCGTCCTC
AGCACCCGCGTCGGCTATAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTKYFKNPDAIAALSEEEFYVTQNSGTERPGTGKLLSNKEPGIYVDIVSGEPLFASSDKYESGCGWPSFTKPIEPAHVQE
LEDRTLGMIRTEVRSTHGDSHLGHVFPDGPADRGGLRYCINSASLRFIHLDDMEAEGYGAYINQVEDHR

Sequences:

>Translated_149_residues
MTKYFKNPDAIAALSEEEFYVTQNSGTERPGTGKLLSNKEPGIYVDIVSGEPLFASSDKYESGCGWPSFTKPIEPAHVQE
LEDRTLGMIRTEVRSTHGDSHLGHVFPDGPADRGGLRYCINSASLRFIHLDDMEAEGYGAYINQVEDHR
>Mature_148_residues
TKYFKNPDAIAALSEEEFYVTQNSGTERPGTGKLLSNKEPGIYVDIVSGEPLFASSDKYESGCGWPSFTKPIEPAHVQEL
EDRTLGMIRTEVRSTHGDSHLGHVFPDGPADRGGLRYCINSASLRFIHLDDMEAEGYGAYINQVEDHR

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=121, Percent_Identity=47.9338842975207, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=44, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=44, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=44, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI37620216, Length=118, Percent_Identity=44.0677966101695, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788077, Length=114, Percent_Identity=56.140350877193, Blast_Score=134, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI115532676, Length=126, Percent_Identity=43.6507936507937, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17553450, Length=126, Percent_Identity=43.6507936507937, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319816, Length=123, Percent_Identity=34.1463414634146, Blast_Score=78, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221378662, Length=123, Percent_Identity=44.7154471544715, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221378664, Length=116, Percent_Identity=45.6896551724138, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI45553335, Length=119, Percent_Identity=45.3781512605042, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356369, Length=119, Percent_Identity=45.3781512605042, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645799, Length=119, Percent_Identity=45.3781512605042, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24645801, Length=130, Percent_Identity=41.5384615384615, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24645804, Length=130, Percent_Identity=41.5384615384615, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16538; Mature: 16407

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYFKNPDAIAALSEEEFYVTQNSGTERPGTGKLLSNKEPGIYVDIVSGEPLFASSDKY
CCCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCC
ESGCGWPSFTKPIEPAHVQELEDRTLGMIRTEVRSTHGDSHLGHVFPDGPADRGGLRYCI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFIHLDDMEAEGYGAYINQVEDHR
CCCCEEEEEECCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure 
TKYFKNPDAIAALSEEEFYVTQNSGTERPGTGKLLSNKEPGIYVDIVSGEPLFASSDKY
CCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCC
ESGCGWPSFTKPIEPAHVQELEDRTLGMIRTEVRSTHGDSHLGHVFPDGPADRGGLRYCI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFIHLDDMEAEGYGAYINQVEDHR
CCCCEEEEEECCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]