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The map label for this gene is hupB [H]

Identifier: 99082641

GI number: 99082641

Start: 2963731

End: 2964024

Strand: Direct

Name: hupB [H]

Synonym: TM1040_2801

Alternate gene names: 99082641

Gene position: 2963731-2964024 (Clockwise)

Preceding gene: 99082640

Following gene: 99082642

Centisome position: 92.59

GC content: 58.16

Gene sequence:

>294_bases
ATGTCCAAACCGATGACCAAAACTCAGCTTGTGGCAGCACTGGCTGAGGAAATGGACAGCGACAAGAAAACCGCTGGTGC
CGCTCTGGATGCCGTTTGCAACCTGATCACCCGCGAAGTGTCTGGCGGCGGTGCCGTGACTCTGCCGGGTGTTGGCAAGA
TCTACTGCCGTGAGCGTCCCGAGCGCGAAGTCCGCAACCCGGCAACCGGCGAGAAGTTCATGAAAGAAGCAGACAAGGTC
GTGAAAATGACCATCGCCAAAGCGCTCAAGGACAGCGTCAACGGCGAAGGCTGA

Upstream 100 bases:

>100_bases
GCTTGATCTTGTGCGCTACGCGTTGTGTTGTCCCACTACATAACGCTAATGTTACGCGATGAGGCCCCAACACGTCGGGC
AGTTTCAAGGAGAGCTAAGA

Downstream 100 bases:

>100_bases
TCCACATCTGGATCAAGGCCAATGGCTTCGGGGCTGCCCTTTTGGGCGGCCCTTTTCTTTTGTACCAATCTCTTCGCGCT
GCCTTTCCAGCCTCGCGGCA

Product: histone-like DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSKPMTKTQLVAALAEEMDSDKKTAGAALDAVCNLITREVSGGGAVTLPGVGKIYCRERPEREVRNPATGEKFMKEADKV
VKMTIAKALKDSVNGEG

Sequences:

>Translated_97_residues
MSKPMTKTQLVAALAEEMDSDKKTAGAALDAVCNLITREVSGGGAVTLPGVGKIYCRERPEREVRNPATGEKFMKEADKV
VKMTIAKALKDSVNGEG
>Mature_96_residues
SKPMTKTQLVAALAEEMDSDKKTAGAALDAVCNLITREVSGGGAVTLPGVGKIYCRERPEREVRNPATGEKFMKEADKVV
KMTIAKALKDSVNGEG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=41.1111111111111, Blast_Score=62, Evalue=8e-12,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=40.4494382022472, Blast_Score=58, Evalue=1e-10,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10311; Mature: 10180

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPMTKTQLVAALAEEMDSDKKTAGAALDAVCNLITREVSGGGAVTLPGVGKIYCRERP
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCCC
EREVRNPATGEKFMKEADKVVKMTIAKALKDSVNGEG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKPMTKTQLVAALAEEMDSDKKTAGAALDAVCNLITREVSGGGAVTLPGVGKIYCRERP
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHCCCC
EREVRNPATGEKFMKEADKVVKMTIAKALKDSVNGEG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]