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The map label for this gene is kdgK [H]

Identifier: 99082593

GI number: 99082593

Start: 2901701

End: 2902627

Strand: Direct

Name: kdgK [H]

Synonym: TM1040_2753

Alternate gene names: 99082593

Gene position: 2901701-2902627 (Clockwise)

Preceding gene: 99082592

Following gene: 99082594

Centisome position: 90.65

GC content: 61.6

Gene sequence:

>927_bases
GTGAATACGCCTCAGATCCTCTGTCTTGGTGAGCCGCTGGTAGAGTTCAACCAGACCCCCGAAGGCCCCTTTGCCATGGG
GTTTGGTGGCGATGTCTCCAACGTCGCCATCTCCGCCGCCCGTCACGGCGCACAGACCGGGTTGATCACCCGCGTGGGCG
ATGATCCGTTTGGCGCAGCGCTCTGCGATCTTTGGGCCAACGAAGGCCTTGTAACTGATCATGCAGCGCGTGCTCAGGGA
GAGGAAACAGGGGTCTATTTCGTGACCCATGATGCCAGCGGCCATCATTTCACCTACCGCCGCAAGGGCTCTGCCGCATC
GCGCCTGACACCTCAAGATCTGCCGATGAACGCCCTACAGACCTGCCCCATTTTCTACGCCTCTGGCATCAGCCTTGCAG
TGTCATCGAGCATGCAGGATGCGGTCATCGAAGCCGCCCAACAGGCGCGCGCTGGTGGCGGTATTTTTGCCTTTGACCCC
AATCTGCGCGTGGCGCTCTGGCCGCTTGAGGTCGCGCGTGAGACCACGCATCGCTGCATGCAGATCTGCGACGTGGCCTT
GCCAGGGCTTGAGGATGCGCGCCAGTTGACCGGCCTGCATGATGCCAAGGACATCGCCAGCTTTTATCACGAGCTGGGAC
CACGCATTGTCGCACTGACGCTTGGCGCCGAAGGTGTTCTGATCTCAGTCGAAGGCACGCAGCGCGTTCTTTCCGGGCAC
CGGGTCGATGCCAAGGACGCCACCGGCGCAGGCGATTGTTTCAACGGAGCGTTCCTCGCGACCCTCTTGGCCACGAACGA
TCCTTTTTCAGCGGCAGAGCACGCCAATATGGCGGCGGCTCTGTCGACCACTGGATATGGCGCTGTGACGCCGATCCCAA
CCCTTTCCCAAACCCGCAGCGCGCTTGAAACCGCTCAGCGGGCCTAA

Upstream 100 bases:

>100_bases
ACCACGCCTGCGTTGTCGCCAATATGCTCGATCATATCACCCTGATGCGCGCGGAAGAGGTCGCAGGTCAGGAAACCGTC
GCGGCACGGGGGCAAGTTTG

Downstream 100 bases:

>100_bases
ACTCCCCAACTATCAGGAGACTCCTCATGACTATCGAACGTATCGGCGCAGAGCGCACCGGCGCAGGTGGACAGAACCTG
CCGTTTTCCCCTGCCACCCG

Product: PfkB

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNTPQILCLGEPLVEFNQTPEGPFAMGFGGDVSNVAISAARHGAQTGLITRVGDDPFGAALCDLWANEGLVTDHAARAQG
EETGVYFVTHDASGHHFTYRRKGSAASRLTPQDLPMNALQTCPIFYASGISLAVSSSMQDAVIEAAQQARAGGGIFAFDP
NLRVALWPLEVARETTHRCMQICDVALPGLEDARQLTGLHDAKDIASFYHELGPRIVALTLGAEGVLISVEGTQRVLSGH
RVDAKDATGAGDCFNGAFLATLLATNDPFSAAEHANMAAALSTTGYGAVTPIPTLSQTRSALETAQRA

Sequences:

>Translated_308_residues
MNTPQILCLGEPLVEFNQTPEGPFAMGFGGDVSNVAISAARHGAQTGLITRVGDDPFGAALCDLWANEGLVTDHAARAQG
EETGVYFVTHDASGHHFTYRRKGSAASRLTPQDLPMNALQTCPIFYASGISLAVSSSMQDAVIEAAQQARAGGGIFAFDP
NLRVALWPLEVARETTHRCMQICDVALPGLEDARQLTGLHDAKDIASFYHELGPRIVALTLGAEGVLISVEGTQRVLSGH
RVDAKDATGAGDCFNGAFLATLLATNDPFSAAEHANMAAALSTTGYGAVTPIPTLSQTRSALETAQRA
>Mature_308_residues
MNTPQILCLGEPLVEFNQTPEGPFAMGFGGDVSNVAISAARHGAQTGLITRVGDDPFGAALCDLWANEGLVTDHAARAQG
EETGVYFVTHDASGHHFTYRRKGSAASRLTPQDLPMNALQTCPIFYASGISLAVSSSMQDAVIEAAQQARAGGGIFAFDP
NLRVALWPLEVARETTHRCMQICDVALPGLEDARQLTGLHDAKDIASFYHELGPRIVALTLGAEGVLISVEGTQRVLSGH
RVDAKDATGAGDCFNGAFLATLLATNDPFSAAEHANMAAALSTTGYGAVTPIPTLSQTRSALETAQRA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=282, Percent_Identity=28.0141843971631, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87082281, Length=303, Percent_Identity=27.0627062706271, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1790193, Length=245, Percent_Identity=31.0204081632653, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87081971, Length=323, Percent_Identity=25.3869969040248, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17532905, Length=289, Percent_Identity=26.2975778546713, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 32335; Mature: 32335

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPQILCLGEPLVEFNQTPEGPFAMGFGGDVSNVAISAARHGAQTGLITRVGDDPFGAA
CCCCCEEEECCCHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHH
LCDLWANEGLVTDHAARAQGEETGVYFVTHDASGHHFTYRRKGSAASRLTPQDLPMNALQ
HHHHHCCCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHH
TCPIFYASGISLAVSSSMQDAVIEAAQQARAGGGIFAFDPNLRVALWPLEVARETTHRCM
HCCHHEECCCCEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHHHH
QICDVALPGLEDARQLTGLHDAKDIASFYHELGPRIVALTLGAEGVLISVEGTQRVLSGH
HHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEEECCHHHHHCCC
RVDAKDATGAGDCFNGAFLATLLATNDPFSAAEHANMAAALSTTGYGAVTPIPTLSQTRS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCHHEEEECCCCCCCCCCCCHHHHHH
ALETAQRA
HHHHHHCC
>Mature Secondary Structure
MNTPQILCLGEPLVEFNQTPEGPFAMGFGGDVSNVAISAARHGAQTGLITRVGDDPFGAA
CCCCCEEEECCCHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCHHHH
LCDLWANEGLVTDHAARAQGEETGVYFVTHDASGHHFTYRRKGSAASRLTPQDLPMNALQ
HHHHHCCCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCHHHH
TCPIFYASGISLAVSSSMQDAVIEAAQQARAGGGIFAFDPNLRVALWPLEVARETTHRCM
HCCHHEECCCCEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHHHHHHHHHH
QICDVALPGLEDARQLTGLHDAKDIASFYHELGPRIVALTLGAEGVLISVEGTQRVLSGH
HHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCEEEEEECCHHHHHCCC
RVDAKDATGAGDCFNGAFLATLLATNDPFSAAEHANMAAALSTTGYGAVTPIPTLSQTRS
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHCCHHEEEECCCCCCCCCCCCHHHHHH
ALETAQRA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]