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The map label for this gene is glpR [H]

Identifier: 99082514

GI number: 99082514

Start: 2809876

End: 2810637

Strand: Direct

Name: glpR [H]

Synonym: TM1040_2674

Alternate gene names: 99082514

Gene position: 2809876-2810637 (Clockwise)

Preceding gene: 99082513

Following gene: 99082519

Centisome position: 87.78

GC content: 66.54

Gene sequence:

>762_bases
ATGAATGCCACCGACCTGAGCGAGAGACAGCGCGATATTCTGCGGCTGCTGGAGCAAAGCGGCTTTGCCACCATCGAGGA
TCTGGCGGGGCGTTTTGGCGTCACCACACAGACCATCCGCCGCGATGTCAACGACCTGCGCGACCGGGCACTGCTGATGC
GGGTGCATCGGGGCGTCAGGCCGCATGAGGGCGCGCGGCCTTATGCCTCGCGCGCTGTGGAGCAACAGCGTGAGAAGGCC
GCATTGGCGCGCGAGGTGCTGCGGCTCATTCCGGCGGGGGCGTCGGTGTCGATCGGTCTTGGCAGCACCCCGGCAGAGGT
GGCGCGGCTTTTGGCCCATGCGGGCGGGCGTGACGTCATCACCAACAATCTGGTGGCGGCAAGCCATCTGTGGGACGCCG
AGGACATCACCCTATCGATCTGCGGCGGCGCCGTGCGCGATCGCAGTGTCTCGGGCAGTGCGGCGGCAGAGTTCTTTGCC
GCCTACCGCGTGGATTTTGCGATCTTTGGCGTGGCGGGTGTGGATGACGACGGCGCGCTTTTGGATTTTCGCACCGAAGA
GGCACGCGCGCGGGCCGCGATGCAAACCCACGCACGGCAGTCGGTTCTGGTGCTCGATCAGGTCAAGTTCCAGCGCCGCG
CGCCGGCGCGGGGCGGTTGGCTCCACGATCCCGATTATGTCGTCACAAATGCGCCGCCCCCAAAAGCCCTCGCTGCTGGG
CTCTGCGCGGGGGCCTTGGTGCTGATATCGGAAGCGCCCTAG

Upstream 100 bases:

>100_bases
CCTCAAATGAGCACAAACAGAGCCTAATCAAAGAGTTTTCTTGCATCATGCGCGGCGCCCCCTACAAAGGTAATGTTCGT
ATGAACAGGGGAGCGTGCGG

Downstream 100 bases:

>100_bases
CCGTTCTCGCGCAGGATATTGCCCGCCAGATAGAGCGAGCCGCAGATCAGCACGCGGCTGTCTGGGTCGCGCGCCAGAAT
GGCGGTGAGCGCCTCGGCAA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNATDLSERQRDILRLLEQSGFATIEDLAGRFGVTTQTIRRDVNDLRDRALLMRVHRGVRPHEGARPYASRAVEQQREKA
ALAREVLRLIPAGASVSIGLGSTPAEVARLLAHAGGRDVITNNLVAASHLWDAEDITLSICGGAVRDRSVSGSAAAEFFA
AYRVDFAIFGVAGVDDDGALLDFRTEEARARAAMQTHARQSVLVLDQVKFQRRAPARGGWLHDPDYVVTNAPPPKALAAG
LCAGALVLISEAP

Sequences:

>Translated_253_residues
MNATDLSERQRDILRLLEQSGFATIEDLAGRFGVTTQTIRRDVNDLRDRALLMRVHRGVRPHEGARPYASRAVEQQREKA
ALAREVLRLIPAGASVSIGLGSTPAEVARLLAHAGGRDVITNNLVAASHLWDAEDITLSICGGAVRDRSVSGSAAAEFFA
AYRVDFAIFGVAGVDDDGALLDFRTEEARARAAMQTHARQSVLVLDQVKFQRRAPARGGWLHDPDYVVTNAPPPKALAAG
LCAGALVLISEAP
>Mature_253_residues
MNATDLSERQRDILRLLEQSGFATIEDLAGRFGVTTQTIRRDVNDLRDRALLMRVHRGVRPHEGARPYASRAVEQQREKA
ALAREVLRLIPAGASVSIGLGSTPAEVARLLAHAGGRDVITNNLVAASHLWDAEDITLSICGGAVRDRSVSGSAAAEFFA
AYRVDFAIFGVAGVDDDGALLDFRTEEARARAAMQTHARQSVLVLDQVKFQRRAPARGGWLHDPDYVVTNAPPPKALAAG
LCAGALVLISEAP

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=241, Percent_Identity=37.344398340249, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI87082344, Length=255, Percent_Identity=31.7647058823529, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=26.7241379310345, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789519, Length=245, Percent_Identity=27.7551020408163, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789059, Length=229, Percent_Identity=28.3842794759825, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=29.5652173913043, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790635, Length=217, Percent_Identity=27.1889400921659, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27209; Mature: 27209

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATDLSERQRDILRLLEQSGFATIEDLAGRFGVTTQTIRRDVNDLRDRALLMRVHRGVR
CCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PHEGARPYASRAVEQQREKAALAREVLRLIPAGASVSIGLGSTPAEVARLLAHAGGRDVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCHHH
TNNLVAASHLWDAEDITLSICGGAVRDRSVSGSAAAEFFAAYRVDFAIFGVAGVDDDGAL
HCCHHHHHHCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCE
LDFRTEEARARAAMQTHARQSVLVLDQVKFQRRAPARGGWLHDPDYVVTNAPPPKALAAG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHH
LCAGALVLISEAP
HHHHHHHEEECCC
>Mature Secondary Structure
MNATDLSERQRDILRLLEQSGFATIEDLAGRFGVTTQTIRRDVNDLRDRALLMRVHRGVR
CCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PHEGARPYASRAVEQQREKAALAREVLRLIPAGASVSIGLGSTPAEVARLLAHAGGRDVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCHHH
TNNLVAASHLWDAEDITLSICGGAVRDRSVSGSAAAEFFAAYRVDFAIFGVAGVDDDGAL
HCCHHHHHHCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCE
LDFRTEEARARAAMQTHARQSVLVLDQVKFQRRAPARGGWLHDPDYVVTNAPPPKALAAG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHH
LCAGALVLISEAP
HHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]