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The map label for this gene is ccrMIM [H]

Identifier: 99082489

GI number: 99082489

Start: 2784374

End: 2785543

Strand: Reverse

Name: ccrMIM [H]

Synonym: TM1040_2649

Alternate gene names: 99082489

Gene position: 2785543-2784374 (Counterclockwise)

Preceding gene: 99082490

Following gene: 99082488

Centisome position: 87.02

GC content: 59.06

Gene sequence:

>1170_bases
ATGACTCATCTTGTGGATAACCAGAATGAGCGCAAAAGCGCCGTGGTTATCGAGGCAGAGCAAATGAACAAAACCATCGC
GAAGGGCGCCGCTACGGCGCTCCCTTTAAACACGATTCTTGATGGCGACTGTATCGAGCGGATGGCAAGCCTGCCGTCCA
ATTCGATCGACATGATCTTCGCGGATCCGCCCTATAATCTCCAGCTCAAAGGGCAGTTGCACCGCCCTGACAACTCCAAG
GTGGATGCGGTCGACGACGAGTGGGACCAGTTTTCCAGCTTTGGCGTCTATGACCAGTTCACGCGCGCGTGGTTGAAAGA
GGCCCGCCGGATCCTGAAACCCAATGGCGCGCTTTGGGTGATCGGCTCTTATCACAACATCTTTCGCGTGGGCACGGCGC
TGCAGGACGAGGGCTTCTGGATCCTGAACGATGTGGTCTGGCGCAAGTCGAACCCGATGCCGAACTTCCGTGGCAAGCGC
TACACCAACGCCCATGAGACGATGATCTGGGCGTCGAAATCCGAAGGTGCCAAATATACCTTCAACTACGAGGCGCTGAA
GGCGCTCAACGAAGGTATCCAGATGCGCTCGGACTGGGTGATGCCGATCTGTACCGGCCATGAGCGTCTGAAAGATGCCA
ATGGCGACAAGGCGCATCCGACCCAGAAGCCCGAGGCGCTGTTGCACCGTATTCTGGTGGGCTCTACCAACCCCGGTGAC
GTGGTTCTGGACCCGTTCTTTGGCACCGGCACCACCGGCGCGGTGGCCAAGATGCTCGGGCGGGAGTTCATCGGCATCGA
GCGCGAGGAAGCCTATCGCAAGGTTGCCGAAGAGCGCATCAAGAACGTGCGCAAATTTGACCGTGAGGCGCTGCAGGTCT
CGGCCTCCAAACGGGCAGAGCCACGGGTGCCCTTTGGCCAGCTGGTTGAACGCGGCATGCTGCGTCCGGGCGAGGAGCTC
TATTCGATGAACCGACGCCACAAGGCGAAGGTCCGCGCGGATGGCACCTTGATCGGCGACAATATCAAGGGCTCGATCCA
TCAGGTCGGCGCGCATCTTGAAAATGCGCCCTCCTGCAATGGCTGGACCTACTGGTGCTTCAAGAAGGACGGGAAGACCG
TACCGATTGATGTGCTGCGCCAGCAGATCCGGGCGGAAATGCAAGCCTGA

Upstream 100 bases:

>100_bases
CCCACATCATAGAAGGTCGTTCAAGCCGGTCCACAAGATATTGTATCAAGAGTGAACCGTAGCCTGCTGATTCAAAAAAC
AAATTGACCTCGAATCCGGG

Downstream 100 bases:

>100_bases
CCGGCGCTTAGCCGAATTCCGAATTTATTCGAACGCCGACAGCGCGCTGCCCAAGGGTTCAGCGCGCTGCACCTTGCCCC
GCCGGTCTGGCGGGGTTTTT

Product: DNA methylase N-4/N-6

Products: NA

Alternate protein names: M.CcrMI; Adenine-specific methyltransferase CcrMI [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTHLVDNQNERKSAVVIEAEQMNKTIAKGAATALPLNTILDGDCIERMASLPSNSIDMIFADPPYNLQLKGQLHRPDNSK
VDAVDDEWDQFSSFGVYDQFTRAWLKEARRILKPNGALWVIGSYHNIFRVGTALQDEGFWILNDVVWRKSNPMPNFRGKR
YTNAHETMIWASKSEGAKYTFNYEALKALNEGIQMRSDWVMPICTGHERLKDANGDKAHPTQKPEALLHRILVGSTNPGD
VVLDPFFGTGTTGAVAKMLGREFIGIEREEAYRKVAEERIKNVRKFDREALQVSASKRAEPRVPFGQLVERGMLRPGEEL
YSMNRRHKAKVRADGTLIGDNIKGSIHQVGAHLENAPSCNGWTYWCFKKDGKTVPIDVLRQQIRAEMQA

Sequences:

>Translated_389_residues
MTHLVDNQNERKSAVVIEAEQMNKTIAKGAATALPLNTILDGDCIERMASLPSNSIDMIFADPPYNLQLKGQLHRPDNSK
VDAVDDEWDQFSSFGVYDQFTRAWLKEARRILKPNGALWVIGSYHNIFRVGTALQDEGFWILNDVVWRKSNPMPNFRGKR
YTNAHETMIWASKSEGAKYTFNYEALKALNEGIQMRSDWVMPICTGHERLKDANGDKAHPTQKPEALLHRILVGSTNPGD
VVLDPFFGTGTTGAVAKMLGREFIGIEREEAYRKVAEERIKNVRKFDREALQVSASKRAEPRVPFGQLVERGMLRPGEEL
YSMNRRHKAKVRADGTLIGDNIKGSIHQVGAHLENAPSCNGWTYWCFKKDGKTVPIDVLRQQIRAEMQA
>Mature_388_residues
THLVDNQNERKSAVVIEAEQMNKTIAKGAATALPLNTILDGDCIERMASLPSNSIDMIFADPPYNLQLKGQLHRPDNSKV
DAVDDEWDQFSSFGVYDQFTRAWLKEARRILKPNGALWVIGSYHNIFRVGTALQDEGFWILNDVVWRKSNPMPNFRGKRY
TNAHETMIWASKSEGAKYTFNYEALKALNEGIQMRSDWVMPICTGHERLKDANGDKAHPTQKPEALLHRILVGSTNPGDV
VLDPFFGTGTTGAVAKMLGREFIGIEREEAYRKVAEERIKNVRKFDREALQVSASKRAEPRVPFGQLVERGMLRPGEELY
SMNRRHKAKVRADGTLIGDNIKGSIHQVGAHLENAPSCNGWTYWCFKKDGKTVPIDVLRQQIRAEMQA

Specific function: This methylase recognizes the double-stranded sequence GANTC and causes specific methylation on A-2 on both strands. Ccrm-mediated methylation has important cellular functions. Appears to contribute to the accurate cell-cycle control of DNA replication an

COG id: COG0863

COG function: function code L; DNA modification methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI87082238, Length=269, Percent_Identity=30.8550185873606, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002941
- InterPro:   IPR002052
- InterPro:   IPR001091 [H]

Pfam domain/function: PF01555 N6_N4_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 43968; Mature: 43836

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLVDNQNERKSAVVIEAEQMNKTIAKGAATALPLNTILDGDCIERMASLPSNSIDMIF
CCCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHCCHHHHCCCHHHHHHHHCCCCCCEEEE
ADPPYNLQLKGQLHRPDNSKVDAVDDEWDQFSSFGVYDQFTRAWLKEARRILKPNGALWV
CCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
IGSYHNIFRVGTALQDEGFWILNDVVWRKSNPMPNFRGKRYTNAHETMIWASKSEGAKYT
EECCCCHHHHCCEECCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
FNYEALKALNEGIQMRSDWVMPICTGHERLKDANGDKAHPTQKPEALLHRILVGSTNPGD
ECHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
VVLDPFFGTGTTGAVAKMLGREFIGIEREEAYRKVAEERIKNVRKFDREALQVSASKRAE
EEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRVPFGQLVERGMLRPGEELYSMNRRHKAKVRADGTLIGDNIKGSIHQVGAHLENAPSCN
CCCCHHHHHHHHCCCCCHHHHHCCHHHHCEEEECCEEECCCCCCHHHHHHHHHCCCCCCC
GWTYWCFKKDGKTVPIDVLRQQIRAEMQA
CEEEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
THLVDNQNERKSAVVIEAEQMNKTIAKGAATALPLNTILDGDCIERMASLPSNSIDMIF
CCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHCCHHHHCCCHHHHHHHHCCCCCCEEEE
ADPPYNLQLKGQLHRPDNSKVDAVDDEWDQFSSFGVYDQFTRAWLKEARRILKPNGALWV
CCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEE
IGSYHNIFRVGTALQDEGFWILNDVVWRKSNPMPNFRGKRYTNAHETMIWASKSEGAKYT
EECCCCHHHHCCEECCCCCEEEEHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEE
FNYEALKALNEGIQMRSDWVMPICTGHERLKDANGDKAHPTQKPEALLHRILVGSTNPGD
ECHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
VVLDPFFGTGTTGAVAKMLGREFIGIEREEAYRKVAEERIKNVRKFDREALQVSASKRAE
EEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PRVPFGQLVERGMLRPGEELYSMNRRHKAKVRADGTLIGDNIKGSIHQVGAHLENAPSCN
CCCCHHHHHHHHCCCCCHHHHHCCHHHHCEEEECCEEECCCCCCHHHHHHHHHCCCCCCC
GWTYWCFKKDGKTVPIDVLRQQIRAEMQA
CEEEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8289276 [H]