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The map label for this gene is cyaA [H]

Identifier: 99082459

GI number: 99082459

Start: 2751599

End: 2752744

Strand: Reverse

Name: cyaA [H]

Synonym: TM1040_2619

Alternate gene names: 99082459

Gene position: 2752744-2751599 (Counterclockwise)

Preceding gene: 99082460

Following gene: 99082454

Centisome position: 86.0

GC content: 62.22

Gene sequence:

>1146_bases
TTGCGCCGCTTCTGCGAGGAACTGGTCAACCACGGCGTGCCTCTGTTGCGGATGCAACTGTCGCAGCGCGCGCTGCATCC
GGAATTCGGGGGGATCGGTTTCACCTGGACCCGTCAGGACGGGTTGAATTCCGAGTATTTTGAGCGCGTGGACCACAAGG
AGCCACGCAATGAATGGGTGCAAAGTCCGTTCTTTGCTCTGATCAGCTCGGGCGAAGCGGAGTACTACAGTCGCTTCAGC
CGCGAGGACGAAGCGCGCTTTCCGATCTTTACCCGCCTGAAGGAGATGGGGGCGACGAGCTATTTTGCCCATTGGCAGCC
CTTTGGCGATTTCAGTCAGGCGCAGTTTGACCCCGATAGCCCCAATGCCGAAGGCTTGGTCGCGTCCTGGAGTTTTGATG
GCCCGCCAGAGGAGGCCGAACCCTGTCTCGCGTTGCTGCGCAATGTGTTCGGGACGCTGGCACTGGTGTTGGCCGCTGCC
GGAAACCGGGAGATGGGGCGCGCCCTTTTGCAAGTCTACCTGGGGCGCGATGCCGGGGCGCGGGTGCTGTCGGGTGAGAT
CGCGCGCGGCTCATCGCAACGTATTGATGCAGTGATCTGCCTGTTTGATCTGCGCGGCTTTACGGCCCTCTCAGAGTCGT
TGCCGGGTGAAGAGCTTGTTGATTTGCTCAATGATTACTTCGGTCACGTTGTCCAGCTGATCCAGTCCCATGGGGGCAAT
ATCCTGAAGTTCATGGGCGATGCGGTGATGGCGATGTTCAACCTCGGCACCCTGCAGGAGGACGCGCAGGCGGCCCTGCG
GGCGGTGGCGGAGCTTGGTCCGCGCATGAGGGCCGTGAATGAGGTCCGCGCCGCCGAAGGCCTGCCGCTGGCGGAATACA
CGATGGCCCTGCACGCCGGCGAGATCCTCTATGGCAACATCGGCGCGCCGAACCGGCTGGATTTCACCGTGATTGGCCCG
GCTGTGAACCTGACGGCGCGGATAGCCGACATGCATCGCGCCGTGGAGCGGTCGATCATTCTGTCGGAAGATGTCCGCGA
CGCCGCAGGCGCGGATGGCGCGGATCTGGTGTCCGTGGGCCGTTACATGTTGCGCGGCGTGGCGGAACCCATTGAGCTCT
TTACGCTCTATCAACCGGAAACCTGA

Upstream 100 bases:

>100_bases
TGATCAGCAACAGGGGGATGGGGCCATTCACGCCGCGACCGAGGATCTGAAGAACTGGCTGACCGAACAGGGTCTGAAGG
CGGTAGGGCGCGAAGAGCTC

Downstream 100 bases:

>100_bases
ACACCCAAAAGAGCGGAGCGCCTGAGGGACGTGCCGACCTTTCGAAAGGGGTTTCCCCTCGTGACCGGGTGGACCCGCGC
GCGCCGGGCCTTTGGCCCGG

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRRFCEELVNHGVPLLRMQLSQRALHPEFGGIGFTWTRQDGLNSEYFERVDHKEPRNEWVQSPFFALISSGEAEYYSRFS
REDEARFPIFTRLKEMGATSYFAHWQPFGDFSQAQFDPDSPNAEGLVASWSFDGPPEEAEPCLALLRNVFGTLALVLAAA
GNREMGRALLQVYLGRDAGARVLSGEIARGSSQRIDAVICLFDLRGFTALSESLPGEELVDLLNDYFGHVVQLIQSHGGN
ILKFMGDAVMAMFNLGTLQEDAQAALRAVAELGPRMRAVNEVRAAEGLPLAEYTMALHAGEILYGNIGAPNRLDFTVIGP
AVNLTARIADMHRAVERSIILSEDVRDAAGADGADLVSVGRYMLRGVAEPIELFTLYQPET

Sequences:

>Translated_381_residues
MRRFCEELVNHGVPLLRMQLSQRALHPEFGGIGFTWTRQDGLNSEYFERVDHKEPRNEWVQSPFFALISSGEAEYYSRFS
REDEARFPIFTRLKEMGATSYFAHWQPFGDFSQAQFDPDSPNAEGLVASWSFDGPPEEAEPCLALLRNVFGTLALVLAAA
GNREMGRALLQVYLGRDAGARVLSGEIARGSSQRIDAVICLFDLRGFTALSESLPGEELVDLLNDYFGHVVQLIQSHGGN
ILKFMGDAVMAMFNLGTLQEDAQAALRAVAELGPRMRAVNEVRAAEGLPLAEYTMALHAGEILYGNIGAPNRLDFTVIGP
AVNLTARIADMHRAVERSIILSEDVRDAAGADGADLVSVGRYMLRGVAEPIELFTLYQPET
>Mature_381_residues
MRRFCEELVNHGVPLLRMQLSQRALHPEFGGIGFTWTRQDGLNSEYFERVDHKEPRNEWVQSPFFALISSGEAEYYSRFS
REDEARFPIFTRLKEMGATSYFAHWQPFGDFSQAQFDPDSPNAEGLVASWSFDGPPEEAEPCLALLRNVFGTLALVLAAA
GNREMGRALLQVYLGRDAGARVLSGEIARGSSQRIDAVICLFDLRGFTALSESLPGEELVDLLNDYFGHVVQLIQSHGGN
ILKFMGDAVMAMFNLGTLQEDAQAALRAVAELGPRMRAVNEVRAAEGLPLAEYTMALHAGEILYGNIGAPNRLDFTVIGP
AVNLTARIADMHRAVERSIILSEDVRDAAGADGADLVSVGRYMLRGVAEPIELFTLYQPET

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 42063; Mature: 42063

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFCEELVNHGVPLLRMQLSQRALHPEFGGIGFTWTRQDGLNSEYFERVDHKEPRNEWV
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCHHHHH
QSPFFALISSGEAEYYSRFSREDEARFPIFTRLKEMGATSYFAHWQPFGDFSQAQFDPDS
HCHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCC
PNAEGLVASWSFDGPPEEAEPCLALLRNVFGTLALVLAAAGNREMGRALLQVYLGRDAGA
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
RVLSGEIARGSSQRIDAVICLFDLRGFTALSESLPGEELVDLLNDYFGHVVQLIQSHGGN
HHHHHHHCCCCCHHHHHHHEEHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCH
ILKFMGDAVMAMFNLGTLQEDAQAALRAVAELGPRMRAVNEVRAAEGLPLAEYTMALHAG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHCC
EILYGNIGAPNRLDFTVIGPAVNLTARIADMHRAVERSIILSEDVRDAAGADGADLVSVG
CEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RYMLRGVAEPIELFTLYQPET
HHHHHHHCCHHHHHEECCCCC
>Mature Secondary Structure
MRRFCEELVNHGVPLLRMQLSQRALHPEFGGIGFTWTRQDGLNSEYFERVDHKEPRNEWV
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCHHHHH
QSPFFALISSGEAEYYSRFSREDEARFPIFTRLKEMGATSYFAHWQPFGDFSQAQFDPDS
HCHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCC
PNAEGLVASWSFDGPPEEAEPCLALLRNVFGTLALVLAAAGNREMGRALLQVYLGRDAGA
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
RVLSGEIARGSSQRIDAVICLFDLRGFTALSESLPGEELVDLLNDYFGHVVQLIQSHGGN
HHHHHHHCCCCCHHHHHHHEEHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCH
ILKFMGDAVMAMFNLGTLQEDAQAALRAVAELGPRMRAVNEVRAAEGLPLAEYTMALHAG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHCC
EILYGNIGAPNRLDFTVIGPAVNLTARIADMHRAVERSIILSEDVRDAAGADGADLVSVG
CEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RYMLRGVAEPIELFTLYQPET
HHHHHHHCCHHHHHEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]