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The map label for this gene is pheA [H]

Identifier: 99082394

GI number: 99082394

Start: 2697641

End: 2698471

Strand: Direct

Name: pheA [H]

Synonym: TM1040_2554

Alternate gene names: 99082394

Gene position: 2697641-2698471 (Clockwise)

Preceding gene: 99082388

Following gene: 99082408

Centisome position: 84.28

GC content: 60.77

Gene sequence:

>831_bases
ATGACCCAGAAAATCGCAATTCAGGGCGAACTCGGCTCCTACAGCCACGAGGCCTGCCGCAACAAACGGCCCGATATGGA
GGTGCTGCCCTGCCGGGGATTTGAGGATGCCATCAACGCCGTGCGCTCCGGCGAGGCCGAGCTCGCGATGCTGCCGGTGG
AAAACACCACCTATGGCCGGGTCGCAGATATTCACCGCCTGCTGCCCCATTCCGGCCTCAAGATCATCGATGAGGCTTTT
GTGCGCGTCCACATCAACCTCCTGGGGGTGCCCGGAGCCACCCTTGATGACATCAAGGAAGCGCATTCGCATCTGGTGCT
GTTGCCACAATGCGCAACTTTCCTGCGCCAACACCAGATCCAGGGCCGCGTCAGCCCTGACAACGCGCGCGCCGCCCGCG
AGGTGGCCGAGCGCGGGGAGATCACCCACGCTGCGCTCGCGTCGGAACTGGCCGGTGAGATCTACGGTCTCAATGTACTG
GCCCGCCACATTGAGGATCAGGGCAACAACACCACGCGGTTCCTGACCATGGCACGCGAGGCCGATACAAGCCGCCGCGG
CGATAACGGCATGATCACCAGTTTTGTCTTTCAGGTACGCAACATTCCCGCCGCGCTTTATAAGGCGATGGGCGGGTTTG
CCACCAATGGCGTCAACATGACCAAGCTCGAGAGCTACATGGTCAATGGCTCTTTTACGGCGACCCAGTTCTATGCCGAC
ATCGACGGCCACCCGGAGGATGAGAACGTCCGCCTCGCCATGGATGAGCTGAGCTATTTCACAACCGATGTGGAAATCCT
CGGCGTCTATCCCGCAGATCGCAAACGCTGA

Upstream 100 bases:

>100_bases
TGTCTAACAGGGTGTCTAAGGCTTCCCCTATCAACTGGCAAGGTATAGACACCGCGACTAAACGACCAAATTCCCAAGTT
TTTGCAAAGATGACGCAGCT

Downstream 100 bases:

>100_bases
GGGCGCAAACTGGCCCCGTTGATTGGGGCCAGCCACAGATACACGGATCGGCCTTAGCCGATCATCGCACCATCTTCGCG
CCAGACCGCCACGATCGACG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTQKIAIQGELGSYSHEACRNKRPDMEVLPCRGFEDAINAVRSGEAELAMLPVENTTYGRVADIHRLLPHSGLKIIDEAF
VRVHINLLGVPGATLDDIKEAHSHLVLLPQCATFLRQHQIQGRVSPDNARAAREVAERGEITHAALASELAGEIYGLNVL
ARHIEDQGNNTTRFLTMAREADTSRRGDNGMITSFVFQVRNIPAALYKAMGGFATNGVNMTKLESYMVNGSFTATQFYAD
IDGHPEDENVRLAMDELSYFTTDVEILGVYPADRKR

Sequences:

>Translated_276_residues
MTQKIAIQGELGSYSHEACRNKRPDMEVLPCRGFEDAINAVRSGEAELAMLPVENTTYGRVADIHRLLPHSGLKIIDEAF
VRVHINLLGVPGATLDDIKEAHSHLVLLPQCATFLRQHQIQGRVSPDNARAAREVAERGEITHAALASELAGEIYGLNVL
ARHIEDQGNNTTRFLTMAREADTSRRGDNGMITSFVFQVRNIPAALYKAMGGFATNGVNMTKLESYMVNGSFTATQFYAD
IDGHPEDENVRLAMDELSYFTTDVEILGVYPADRKR
>Mature_275_residues
TQKIAIQGELGSYSHEACRNKRPDMEVLPCRGFEDAINAVRSGEAELAMLPVENTTYGRVADIHRLLPHSGLKIIDEAFV
RVHINLLGVPGATLDDIKEAHSHLVLLPQCATFLRQHQIQGRVSPDNARAAREVAERGEITHAALASELAGEIYGLNVLA
RHIEDQGNNTTRFLTMAREADTSRRGDNGMITSFVFQVRNIPAALYKAMGGFATNGVNMTKLESYMVNGSFTATQFYADI
DGHPEDENVRLAMDELSYFTTDVEILGVYPADRKR

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=276, Percent_Identity=32.9710144927536, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30514; Mature: 30383

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKIAIQGELGSYSHEACRNKRPDMEVLPCRGFEDAINAVRSGEAELAMLPVENTTYGR
CCCEEEEECCCCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCH
VADIHRLLPHSGLKIIDEAFVRVHINLLGVPGATLDDIKEAHSHLVLLPQCATFLRQHQI
HHHHHHHCCCCCHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCEEEHHHHHHHHHHHHH
QGRVSPDNARAAREVAERGEITHAALASELAGEIYGLNVLARHIEDQGNNTTRFLTMARE
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHH
ADTSRRGDNGMITSFVFQVRNIPAALYKAMGGFATNGVNMTKLESYMVNGSFTATQFYAD
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHEEECCCEEEEEEEEE
IDGHPEDENVRLAMDELSYFTTDVEILGVYPADRKR
CCCCCCCCCEEEEHHHHHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TQKIAIQGELGSYSHEACRNKRPDMEVLPCRGFEDAINAVRSGEAELAMLPVENTTYGR
CCEEEEECCCCCCCHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCH
VADIHRLLPHSGLKIIDEAFVRVHINLLGVPGATLDDIKEAHSHLVLLPQCATFLRQHQI
HHHHHHHCCCCCHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHCEEEHHHHHHHHHHHHH
QGRVSPDNARAAREVAERGEITHAALASELAGEIYGLNVLARHIEDQGNNTTRFLTMARE
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHH
ADTSRRGDNGMITSFVFQVRNIPAALYKAMGGFATNGVNMTKLESYMVNGSFTATQFYAD
CCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHEEECCCEEEEEEEEE
IDGHPEDENVRLAMDELSYFTTDVEILGVYPADRKR
CCCCCCCCCEEEEHHHHHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]