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The map label for this gene is ruvB [H]

Identifier: 99082211

GI number: 99082211

Start: 2491837

End: 2492856

Strand: Reverse

Name: ruvB [H]

Synonym: TM1040_2371

Alternate gene names: 99082211

Gene position: 2492856-2491837 (Counterclockwise)

Preceding gene: 99082212

Following gene: 99082210

Centisome position: 77.88

GC content: 63.63

Gene sequence:

>1020_bases
ATGATTGATGCAGACCCCACCCTGCGCCCGGAGCCTCTGCCCGAAGACAATGATCGCGCCCTGCGCCCGCAGGGCCTGGG
TGAGTTTATTGGCCAGGCCGAAGCCCGGGCAAACCTGCGGGTGTTCATCGAATCCGCCCGTCGCCGTGGCGAGGCTATGG
ATCACACGCTGTTTCATGGCCCTCCAGGCCTCGGCAAGACCACTCTGGCACAGATCGTTGCGCGCGAGCTGGGCGTAAAT
TTCCGGATGACATCGGGCCCGGTGCTTGCGAAGGCCGGAGATCTGGCGGCAATCCTGACCAACCTTGAGGCGCGCGATGT
GTTGTTCATCGACGAAATTCACCGCCTGAACCCTGCCGTCGAGGAAGTCCTTTACCCGGCGATGGAGGATTTCGAGCTGG
ATCTCGTGATTGGGGAGGGGCCAGCCGCGCGTACGGTGCGTATCGAGTTGCAGCCCTTCACGCTTGTGGGGGCCACCACC
CGGATGGGGCTTTTGACCACACCGCTGCGGGATCGGTTTGGGATTCCAACCCGGCTGCAGTTTTACACCATCGACGAGCT
TTTTGAGATTGTCAGCCGAAACGCGCGCAAACTGGGCGCGCCCGCCGATGACGCAGGCGCGCGTGAGATCGCGCGGCGCG
CGCGCGGCACCCCAAGGATCGCCGGACGGCTCTTGCGCCGCGTGGTGGACTTTGCGGTTGTCGAGGGCGATGGCACTATC
ACCCGCGAACTGGCGGATGGGGCTCTGACACGGCTTGGCGTGGATCAGCTGGGCCTTGATGGCGCGGACCGACGCTATTT
GCGACTGGTTGCGGAGAATTATGGTGGGGGCCCTGTCGGCATCGAAACCATGTCCGCCGCCCTGAGCGAAAGCCGCGATG
CGCTGGAAGAGGTGATCGAGCCCTATCTGCTGCAGCAGGGCCTTATTCAGCGCACGCCGCGCGGTCGGATGCTGGCGCAA
AAGGCCTGGACTCATCTCGGGATTGCGCCGCCTAAATCCCAGAGCGATCTCTTTGGCTGA

Upstream 100 bases:

>100_bases
CGGTCGCAGAGGCCGCCGCCAACAATCCAGACGCAGGCGAAGCGGAATTGATCCGTGCCGCGCTTCGGCTCTTGGCACCC
AAAGGGTGAGGACGCTTTGA

Downstream 100 bases:

>100_bases
CACCGTGGGTAGCGGCGCAGGCCGAAGAGTTTCTAGATCGATCACGGATCAATGACAGGCCGGCAACGCGCCTGATGCAG
CCCAATGGCGGCGGGCCCAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIDADPTLRPEPLPEDNDRALRPQGLGEFIGQAEARANLRVFIESARRRGEAMDHTLFHGPPGLGKTTLAQIVARELGVN
FRMTSGPVLAKAGDLAAILTNLEARDVLFIDEIHRLNPAVEEVLYPAMEDFELDLVIGEGPAARTVRIELQPFTLVGATT
RMGLLTTPLRDRFGIPTRLQFYTIDELFEIVSRNARKLGAPADDAGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGTI
TRELADGALTRLGVDQLGLDGADRRYLRLVAENYGGGPVGIETMSAALSESRDALEEVIEPYLLQQGLIQRTPRGRMLAQ
KAWTHLGIAPPKSQSDLFG

Sequences:

>Translated_339_residues
MIDADPTLRPEPLPEDNDRALRPQGLGEFIGQAEARANLRVFIESARRRGEAMDHTLFHGPPGLGKTTLAQIVARELGVN
FRMTSGPVLAKAGDLAAILTNLEARDVLFIDEIHRLNPAVEEVLYPAMEDFELDLVIGEGPAARTVRIELQPFTLVGATT
RMGLLTTPLRDRFGIPTRLQFYTIDELFEIVSRNARKLGAPADDAGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGTI
TRELADGALTRLGVDQLGLDGADRRYLRLVAENYGGGPVGIETMSAALSESRDALEEVIEPYLLQQGLIQRTPRGRMLAQ
KAWTHLGIAPPKSQSDLFG
>Mature_339_residues
MIDADPTLRPEPLPEDNDRALRPQGLGEFIGQAEARANLRVFIESARRRGEAMDHTLFHGPPGLGKTTLAQIVARELGVN
FRMTSGPVLAKAGDLAAILTNLEARDVLFIDEIHRLNPAVEEVLYPAMEDFELDLVIGEGPAARTVRIELQPFTLVGATT
RMGLLTTPLRDRFGIPTRLQFYTIDELFEIVSRNARKLGAPADDAGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGTI
TRELADGALTRLGVDQLGLDGADRRYLRLVAENYGGGPVGIETMSAALSESRDALEEVIEPYLLQQGLIQRTPRGRMLAQ
KAWTHLGIAPPKSQSDLFG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=334, Percent_Identity=61.377245508982, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37113; Mature: 37113

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDADPTLRPEPLPEDNDRALRPQGLGEFIGQAEARANLRVFIESARRRGEAMDHTLFHG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHCCC
PPGLGKTTLAQIVARELGVNFRMTSGPVLAKAGDLAAILTNLEARDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHCCHHH
EEVLYPAMEDFELDLVIGEGPAARTVRIELQPFTLVGATTRMGLLTTPLRDRFGIPTRLQ
HHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCHHHCCCEECCHHHHCCCCCEEE
FYTIDELFEIVSRNARKLGAPADDAGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGTI
EEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCC
TRELADGALTRLGVDQLGLDGADRRYLRLVAENYGGGPVGIETMSAALSESRDALEEVIE
HHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
PYLLQQGLIQRTPRGRMLAQKAWTHLGIAPPKSQSDLFG
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDADPTLRPEPLPEDNDRALRPQGLGEFIGQAEARANLRVFIESARRRGEAMDHTLFHG
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHCCC
PPGLGKTTLAQIVARELGVNFRMTSGPVLAKAGDLAAILTNLEARDVLFIDEIHRLNPAV
CCCCCHHHHHHHHHHHHCCCEEECCCCCEECCCHHHHHHHCCCCCCCHHHHHHHHCCHHH
EEVLYPAMEDFELDLVIGEGPAARTVRIELQPFTLVGATTRMGLLTTPLRDRFGIPTRLQ
HHHHHHHHCCCEEEEEECCCCCCEEEEEEECCEEEECCHHHCCCEECCHHHHCCCCCEEE
FYTIDELFEIVSRNARKLGAPADDAGAREIARRARGTPRIAGRLLRRVVDFAVVEGDGTI
EEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCC
TRELADGALTRLGVDQLGLDGADRRYLRLVAENYGGGPVGIETMSAALSESRDALEEVIE
HHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
PYLLQQGLIQRTPRGRMLAQKAWTHLGIAPPKSQSDLFG
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA