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The map label for this gene is tolQ [H]

Identifier: 99082208

GI number: 99082208

Start: 2489742

End: 2490437

Strand: Reverse

Name: tolQ [H]

Synonym: TM1040_2368

Alternate gene names: 99082208

Gene position: 2490437-2489742 (Counterclockwise)

Preceding gene: 99082209

Following gene: 99082207

Centisome position: 77.8

GC content: 58.62

Gene sequence:

>696_bases
ATGGAAGCAGAAACTCTGGCACTGGCACAGGAGATTGATTTCTCCATGTGGGGGCTGTTCGCACGCGCGACGCTCACCGT
AAAACTTGTGATGATCATGTTGATCGTGGCGTCGATCTGGTCGTGGTCCATTATCATTCAGAAAGTGATCACCTATCGCA
CAGCACGTCGCGAAGCGCAGGTGTTTGAGCGCGCCTTTTGGTCCGGCAACCCGCTGGACGAGCTGTTTGAGGAGATCGGA
GCCGAGCCCTCGGGCCGGTCAGAGCGCATCTTTGCAGCTGGCATGATCGAATGGCGCCGCAGTCACCGAACGGACGGAGC
GCTGATACCGGGCGCGCAGGCGCGCATCGACCGCTCCATGGATGTGGCGATCTCCAAGGAGAGCGAGGGTCTTCAGAGCG
GACTACAGGTGCTGGCGACCATCGGCTCGACCACGCCCTTCATCGGGCTTTTCGGAACGGTCTGGGGTATCATGAATGCG
TTCATCGAGATCGCAGAGCAGCAAAACACCAACCTTGCCGTTGTCGCACCGGGGATTGCCGAGGCGCTTTTGGCGACGGG
GCTGGGGCTATTGGCTGCGATCCCGGCGGTGATCTTTTATAACAAACTCTCGGCGGATTCTGATCGCATCATTGGCGGCT
ATGAGGCCTTTGCTGATGAATTCGCGACCATCTTCTCGCGCCAGTTGGACAGCTGA

Upstream 100 bases:

>100_bases
CCCCCTGTTTCCTTGGCAATGTCGCTTGTTTTGCGCTAGCGTTCGCCCCAATTGGGCTGCGCAACCTAAACGACGCGGCA
ACTGGCGATAGAGCAGGCAG

Downstream 100 bases:

>100_bases
GCCATGGGAGCCGGTGTTCAGACAAAGGATGCAGGCGGTGGCCGCCGGCGCGGACGGCGTCGGTCGCGCGCGCGCCCGAT
GGCAGAGATCAACATCACGC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEAETLALAQEIDFSMWGLFARATLTVKLVMIMLIVASIWSWSIIIQKVITYRTARREAQVFERAFWSGNPLDELFEEIG
AEPSGRSERIFAAGMIEWRRSHRTDGALIPGAQARIDRSMDVAISKESEGLQSGLQVLATIGSTTPFIGLFGTVWGIMNA
FIEIAEQQNTNLAVVAPGIAEALLATGLGLLAAIPAVIFYNKLSADSDRIIGGYEAFADEFATIFSRQLDS

Sequences:

>Translated_231_residues
MEAETLALAQEIDFSMWGLFARATLTVKLVMIMLIVASIWSWSIIIQKVITYRTARREAQVFERAFWSGNPLDELFEEIG
AEPSGRSERIFAAGMIEWRRSHRTDGALIPGAQARIDRSMDVAISKESEGLQSGLQVLATIGSTTPFIGLFGTVWGIMNA
FIEIAEQQNTNLAVVAPGIAEALLATGLGLLAAIPAVIFYNKLSADSDRIIGGYEAFADEFATIFSRQLDS
>Mature_231_residues
MEAETLALAQEIDFSMWGLFARATLTVKLVMIMLIVASIWSWSIIIQKVITYRTARREAQVFERAFWSGNPLDELFEEIG
AEPSGRSERIFAAGMIEWRRSHRTDGALIPGAQARIDRSMDVAISKESEGLQSGLQVLATIGSTTPFIGLFGTVWGIMNA
FIEIAEQQNTNLAVVAPGIAEALLATGLGLLAAIPAVIFYNKLSADSDRIIGGYEAFADEFATIFSRQLDS

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=222, Percent_Identity=44.1441441441441, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1789381, Length=228, Percent_Identity=40.3508771929825, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25280; Mature: 25280

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAETLALAQEIDFSMWGLFARATLTVKLVMIMLIVASIWSWSIIIQKVITYRTARREAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFERAFWSGNPLDELFEEIGAEPSGRSERIFAAGMIEWRRSHRTDGALIPGAQARIDRSM
HHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCH
DVAISKESEGLQSGLQVLATIGSTTPFIGLFGTVWGIMNAFIEIAEQQNTNLAVVAPGIA
HHEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHH
EALLATGLGLLAAIPAVIFYNKLSADSDRIIGGYEAFADEFATIFSRQLDS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEAETLALAQEIDFSMWGLFARATLTVKLVMIMLIVASIWSWSIIIQKVITYRTARREAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFERAFWSGNPLDELFEEIGAEPSGRSERIFAAGMIEWRRSHRTDGALIPGAQARIDRSM
HHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCH
DVAISKESEGLQSGLQVLATIGSTTPFIGLFGTVWGIMNAFIEIAEQQNTNLAVVAPGIA
HHEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHH
EALLATGLGLLAAIPAVIFYNKLSADSDRIIGGYEAFADEFATIFSRQLDS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]