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The map label for this gene is namA [H]

Identifier: 99082083

GI number: 99082083

Start: 2356185

End: 2358479

Strand: Reverse

Name: namA [H]

Synonym: TM1040_2243

Alternate gene names: 99082083

Gene position: 2358479-2356185 (Counterclockwise)

Preceding gene: 99082084

Following gene: 99082082

Centisome position: 73.68

GC content: 61.44

Gene sequence:

>2295_bases
ATGCGCATTGCATGCTTGGGAGGGGGGCCAGCGGGCCTGTATTTCGGGATCTCGATGAAGCTGCGTGATCCCAGCCATGA
GGTCACGGTGATCGAACGCAATCGGGCCGATGACACCTTTGGCTGGGGCGTGGTGCTCTCGGATGAGACGCTCGACAATC
TGGCAGCCAATGACGCCAAGAGCGCCGAGTCGATCCGGTCTCATTTTGCCTATTGGGATGATGTCGCGCTTCTGTTCAAA
GGCACGCGGCAGGTGTCCTCTGGTCATGGGTTCTGCGGCATCGGGCGCAAGAAGCTGCTGATCCTTCTGCAGGAGCGCGC
CCGTGAACTGGGCGTCAAGATGCAGTTCGAAACCGAAGTGCAAAGCGCCGAGGACTATCGCAAGGATTACGATCTTGTGG
TCGCCAGTGACGGGCTCAATTCGCGCACACGCAGCCTGTATGCCGACACCTTCAAGCCGGATGTGGACACGCGGCTTTGT
AATTTTGTTTGGCTTGGCACCCATCAGACCTTCAAGGATGCGTTCACGTTTATCTTTGAGGAAACCGAGCACGGCTGGGT
CTGGGCGCATGCCTACCAGTTCGACGACGACACCGCGACCTTCATCGTGGAATGCACGCAAGAGACCTTTGACGCCTTTG
GTTTTGGCTCCATGAGCCAGCAGGAAAGCATCAAGACCTGCGAAGAAATCTTCAAGGATCATCTGGGCGGCCATGCGCTG
ATGACCAATGCCAACCATATTCGCGGCTCCGCCTGGATCCGCTTCCCGCGGGTTTTGTGCGAAAAATGGAGTCACGAGAA
TGTGGTCCTGATGGGCGACGCGGCCGCGACGGCGCATTTCTCGATTGGGTCAGGGTCCAAGTTGGCGCTGGAATCCGCGA
TTGCGCTGGCCGATCTGCTGCATGAAAAGCCTGATCTGCAAAGCGCCTTTGACGAATACGAAGACCAGCGCCGTCTTGAG
GTGTTGCGCCTGCAGTCTGCGGCACGCAATTCGATGGAGTGGTTCGAGCGGGTGGAGCGCTATCTGGATCTTGATCCGGT
GCAGCTGAATTACTCGATGCTGACTCGCAGTCAGCGGATCAGCCACGAAAACCTGCGCGAACGGGACAAGGACTGGCTTG
AGAGCGCGGAGCGCTGGTTCATGGATCAGGCGGGGGCGCCCAAGGATGCGCCGCTGCGGGCGCCGATGTTTGCCCCCTTC
CGCCTGCGCGAGATGGACCTCAAGAGCCGCATCGTCGTTTCGCCCATGGCGCAGTACAAGGCCAAGGATGGCAGCCCGAC
CGACTGGCATCTGGTGCATTACGGCGAACGCGCCAAAGGCGGCGCGGGGCTGGTCTACACCGAGATGACCTGTGTATCGC
CAGAGGGCCGGATTACCCCCGGCTGTCCGGGGCTCTATGCGCCGGAGCATGAGGCCGCATGGTCGCGGATCACCGATTTT
GTGCATGCCGAAACCGACGCCAAGATCTGCTGCCAGATCGGCCACTCGGGACGCAAAGGCTCCACCCAGCTTGGTTGGGA
CGAGATGGATGCACCGCTGCCAGAGGGCAACTGGGATATCGTCAGCGCCTCTGCGATCCCGTGGTCTGGGCAGAACGCCA
CCCCGCGCGAAATCACCCGCGCCGAGATGGACGAGGTGCGCGATCAATTTGTGCGCGCGGCTCAGATGGCGGATCGTGCG
GGCTTTGACATGATCGAGCTGCACGCAGCCCATGGCTATCTGATCTCGTCGTTCCTGTCGCCGGTCTCGAACCAGCGCGG
CGATGACTATGGCGGCAGCCTTGAAAACCGCCTGCGCTATCCGCTCGAGGTCTTTGCCGCGATGCGCGCGGTCTGGCCCG
AAGGCAAGCCGATGTCGGTGCGGATCTCCGCCAATGACTGGGTGGGCGAGGATGGCGTCACCCCGGACGAAGCCGTCCAG
ATCGCGCGTGCCTTTTGGGAGGCCGGTGCGGATCTGATCGACGTGTCTGCCGGTCAGACCACCACCGAGGCCAAACCCGT
CTACGGCCGCATGTTCCAGACGCCGTTTTCGGATCAGATCCGCAACGAGGCGGGCATCTGTACCATGGCTGTGGGCAATA
TCTTCGAGGCCGATCATGCCAATTCGATCCTGATGGCAGGCCGCGCGGATCTGGTGGCCGTGGGCCGCCCGCATCTCTCG
GATCCGTATTGGACCCTTCACGAGGGCAGCAAGATCGGTGATCGTGCAGCCCCCGACTGGCCGCTGCCCTATCTGGCGGG
GCGCGATCAGAGCTGGCGTCTTGCGGACAAAGAAGCGGAGACCCTGCGCGCATGA

Upstream 100 bases:

>100_bases
TCGCAGTTAATGCTTTAAAAATAGAAATTTCAAGCTTGAAATTGTTTTGAGATGCGCAGAACCTGACTTCATCAATAACC
GATGTGGGAATGAGGATCAG

Downstream 100 bases:

>100_bases
GCCAAGATCCACGCCAAGAACATGTCCTGATCACGGGCGGCGGCACCGGTGTTGGGGCCGCCTGCGCCCAGGCCTTCGCG
GCCCAGGGGGCCAAAGTGAC

Product: salicylyl-CoA 5-hydroxylase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 764; Mature: 764

Protein sequence:

>764_residues
MRIACLGGGPAGLYFGISMKLRDPSHEVTVIERNRADDTFGWGVVLSDETLDNLAANDAKSAESIRSHFAYWDDVALLFK
GTRQVSSGHGFCGIGRKKLLILLQERARELGVKMQFETEVQSAEDYRKDYDLVVASDGLNSRTRSLYADTFKPDVDTRLC
NFVWLGTHQTFKDAFTFIFEETEHGWVWAHAYQFDDDTATFIVECTQETFDAFGFGSMSQQESIKTCEEIFKDHLGGHAL
MTNANHIRGSAWIRFPRVLCEKWSHENVVLMGDAAATAHFSIGSGSKLALESAIALADLLHEKPDLQSAFDEYEDQRRLE
VLRLQSAARNSMEWFERVERYLDLDPVQLNYSMLTRSQRISHENLRERDKDWLESAERWFMDQAGAPKDAPLRAPMFAPF
RLREMDLKSRIVVSPMAQYKAKDGSPTDWHLVHYGERAKGGAGLVYTEMTCVSPEGRITPGCPGLYAPEHEAAWSRITDF
VHAETDAKICCQIGHSGRKGSTQLGWDEMDAPLPEGNWDIVSASAIPWSGQNATPREITRAEMDEVRDQFVRAAQMADRA
GFDMIELHAAHGYLISSFLSPVSNQRGDDYGGSLENRLRYPLEVFAAMRAVWPEGKPMSVRISANDWVGEDGVTPDEAVQ
IARAFWEAGADLIDVSAGQTTTEAKPVYGRMFQTPFSDQIRNEAGICTMAVGNIFEADHANSILMAGRADLVAVGRPHLS
DPYWTLHEGSKIGDRAAPDWPLPYLAGRDQSWRLADKEAETLRA

Sequences:

>Translated_764_residues
MRIACLGGGPAGLYFGISMKLRDPSHEVTVIERNRADDTFGWGVVLSDETLDNLAANDAKSAESIRSHFAYWDDVALLFK
GTRQVSSGHGFCGIGRKKLLILLQERARELGVKMQFETEVQSAEDYRKDYDLVVASDGLNSRTRSLYADTFKPDVDTRLC
NFVWLGTHQTFKDAFTFIFEETEHGWVWAHAYQFDDDTATFIVECTQETFDAFGFGSMSQQESIKTCEEIFKDHLGGHAL
MTNANHIRGSAWIRFPRVLCEKWSHENVVLMGDAAATAHFSIGSGSKLALESAIALADLLHEKPDLQSAFDEYEDQRRLE
VLRLQSAARNSMEWFERVERYLDLDPVQLNYSMLTRSQRISHENLRERDKDWLESAERWFMDQAGAPKDAPLRAPMFAPF
RLREMDLKSRIVVSPMAQYKAKDGSPTDWHLVHYGERAKGGAGLVYTEMTCVSPEGRITPGCPGLYAPEHEAAWSRITDF
VHAETDAKICCQIGHSGRKGSTQLGWDEMDAPLPEGNWDIVSASAIPWSGQNATPREITRAEMDEVRDQFVRAAQMADRA
GFDMIELHAAHGYLISSFLSPVSNQRGDDYGGSLENRLRYPLEVFAAMRAVWPEGKPMSVRISANDWVGEDGVTPDEAVQ
IARAFWEAGADLIDVSAGQTTTEAKPVYGRMFQTPFSDQIRNEAGICTMAVGNIFEADHANSILMAGRADLVAVGRPHLS
DPYWTLHEGSKIGDRAAPDWPLPYLAGRDQSWRLADKEAETLRA
>Mature_764_residues
MRIACLGGGPAGLYFGISMKLRDPSHEVTVIERNRADDTFGWGVVLSDETLDNLAANDAKSAESIRSHFAYWDDVALLFK
GTRQVSSGHGFCGIGRKKLLILLQERARELGVKMQFETEVQSAEDYRKDYDLVVASDGLNSRTRSLYADTFKPDVDTRLC
NFVWLGTHQTFKDAFTFIFEETEHGWVWAHAYQFDDDTATFIVECTQETFDAFGFGSMSQQESIKTCEEIFKDHLGGHAL
MTNANHIRGSAWIRFPRVLCEKWSHENVVLMGDAAATAHFSIGSGSKLALESAIALADLLHEKPDLQSAFDEYEDQRRLE
VLRLQSAARNSMEWFERVERYLDLDPVQLNYSMLTRSQRISHENLRERDKDWLESAERWFMDQAGAPKDAPLRAPMFAPF
RLREMDLKSRIVVSPMAQYKAKDGSPTDWHLVHYGERAKGGAGLVYTEMTCVSPEGRITPGCPGLYAPEHEAAWSRITDF
VHAETDAKICCQIGHSGRKGSTQLGWDEMDAPLPEGNWDIVSASAIPWSGQNATPREITRAEMDEVRDQFVRAAQMADRA
GFDMIELHAAHGYLISSFLSPVSNQRGDDYGGSLENRLRYPLEVFAAMRAVWPEGKPMSVRISANDWVGEDGVTPDEAVQ
IARAFWEAGADLIDVSAGQTTTEAKPVYGRMFQTPFSDQIRNEAGICTMAVGNIFEADHANSILMAGRADLVAVGRPHLS
DPYWTLHEGSKIGDRAAPDWPLPYLAGRDQSWRLADKEAETLRA

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=339, Percent_Identity=29.7935103244838, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1789463, Length=335, Percent_Identity=30.1492537313433, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI72001454, Length=320, Percent_Identity=29.6875, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17564188, Length=246, Percent_Identity=30.8943089430894, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=248, Percent_Identity=31.4516129032258, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=248, Percent_Identity=31.4516129032258, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=244, Percent_Identity=30.327868852459, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=264, Percent_Identity=29.1666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17566914, Length=282, Percent_Identity=27.6595744680851, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17566916, Length=265, Percent_Identity=25.2830188679245, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=232, Percent_Identity=30.6034482758621, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=29.0598290598291, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 85582; Mature: 85582

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIACLGGGPAGLYFGISMKLRDPSHEVTVIERNRADDTFGWGVVLSDETLDNLAANDAK
CEEEEECCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCEEEECCCHHHHHHCCCHH
SAESIRSHFAYWDDVALLFKGTRQVSSGHGFCGIGRKKLLILLQERARELGVKMQFETEV
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEHHHH
QSAEDYRKDYDLVVASDGLNSRTRSLYADTFKPDVDTRLCNFVWLGTHQTFKDAFTFIFE
HHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCHHHHEEEEEEECCCHHHHHHHHHHHE
ETEHGWVWAHAYQFDDDTATFIVECTQETFDAFGFGSMSQQESIKTCEEIFKDHLGGHAL
ECCCCEEEEEEEEECCCCEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
MTNANHIRGSAWIRFPRVLCEKWSHENVVLMGDAAATAHFSIGSGSKLALESAIALADLL
EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
HEKPDLQSAFDEYEDQRRLEVLRLQSAARNSMEWFERVERYLDLDPVQLNYSMLTRSQRI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHC
SHENLRERDKDWLESAERWFMDQAGAPKDAPLRAPMFAPFRLREMDLKSRIVVSPMAQYK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCHHHHC
AKDGSPTDWHLVHYGERAKGGAGLVYTEMTCVSPEGRITPGCPGLYAPEHEAAWSRITDF
CCCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
VHAETDAKICCQIGHSGRKGSTQLGWDEMDAPLPEGNWDIVSASAIPWSGQNATPREITR
HHCCCCCHHHEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHH
AEMDEVRDQFVRAAQMADRAGFDMIELHAAHGYLISSFLSPVSNQRGDDYGGSLENRLRY
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
PLEVFAAMRAVWPEGKPMSVRISANDWVGEDGVTPDEAVQIARAFWEAGADLIDVSAGQT
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
TTEAKPVYGRMFQTPFSDQIRNEAGICTMAVGNIFEADHANSILMAGRADLVAVGRPHLS
CCCCCCHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCC
DPYWTLHEGSKIGDRAAPDWPLPYLAGRDQSWRLADKEAETLRA
CCCEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MRIACLGGGPAGLYFGISMKLRDPSHEVTVIERNRADDTFGWGVVLSDETLDNLAANDAK
CEEEEECCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCCCEEEECCCHHHHHHCCCHH
SAESIRSHFAYWDDVALLFKGTRQVSSGHGFCGIGRKKLLILLQERARELGVKMQFETEV
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEECCCHHHHHHHHHHHHHHCCCEEEEHHHH
QSAEDYRKDYDLVVASDGLNSRTRSLYADTFKPDVDTRLCNFVWLGTHQTFKDAFTFIFE
HHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCHHHHEEEEEEECCCHHHHHHHHHHHE
ETEHGWVWAHAYQFDDDTATFIVECTQETFDAFGFGSMSQQESIKTCEEIFKDHLGGHAL
ECCCCEEEEEEEEECCCCEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEE
MTNANHIRGSAWIRFPRVLCEKWSHENVVLMGDAAATAHFSIGSGSKLALESAIALADLL
EECCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHH
HEKPDLQSAFDEYEDQRRLEVLRLQSAARNSMEWFERVERYLDLDPVQLNYSMLTRSQRI
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHC
SHENLRERDKDWLESAERWFMDQAGAPKDAPLRAPMFAPFRLREMDLKSRIVVSPMAQYK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEECCHHHHC
AKDGSPTDWHLVHYGERAKGGAGLVYTEMTCVSPEGRITPGCPGLYAPEHEAAWSRITDF
CCCCCCCCEEEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
VHAETDAKICCQIGHSGRKGSTQLGWDEMDAPLPEGNWDIVSASAIPWSGQNATPREITR
HHCCCCCHHHEEECCCCCCCCCCCCCHHCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHH
AEMDEVRDQFVRAAQMADRAGFDMIELHAAHGYLISSFLSPVSNQRGDDYGGSLENRLRY
HHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCC
PLEVFAAMRAVWPEGKPMSVRISANDWVGEDGVTPDEAVQIARAFWEAGADLIDVSAGQT
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
TTEAKPVYGRMFQTPFSDQIRNEAGICTMAVGNIFEADHANSILMAGRADLVAVGRPHLS
CCCCCCHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCCCEEEECCCCCC
DPYWTLHEGSKIGDRAAPDWPLPYLAGRDQSWRLADKEAETLRA
CCCEEECCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA