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The map label for this gene is paaG [H]

Identifier: 99082080

GI number: 99082080

Start: 2354147

End: 2354950

Strand: Reverse

Name: paaG [H]

Synonym: TM1040_2240

Alternate gene names: 99082080

Gene position: 2354950-2354147 (Counterclockwise)

Preceding gene: 99082081

Following gene: 99082079

Centisome position: 73.57

GC content: 60.45

Gene sequence:

>804_bases
ATGAGCCTCGATGAGACAACGCATTTCAATTGCACGATTGAGGGCGGCATCGCGCGTATCTCGCTCAATCGGCCGGAGCG
TAAGAACCCGCTGACCTTTGAAAGCTACGCAGAGCTGCGCGACTGGTTCCGGGCGTTGCCCTATTCGGACGAGGTGCATG
CGGTTGTGATCGTGCCCAATGGCGGGAATTTTTCCTCTGGCGGGGATGTGCACGACATCATCGGCCCGCTCACCAGGATG
AACATGAAAGAGCTCTTGGCCTTCACCCGCATGACCGGGGATCTTGTGAAGGCGATGCTCAACTGCAGCAAGCCGGTGAT
TTCGGCGGTGGATGGCATTTGTGCGGGGGCAGGGGCGATCATAGCGATGGCCAGTGATCTGCGCATCGCCACACCTGAGG
CCAAGGTGGCGTTTCTCTTTAATCGTGTGGGGCTTGCGGGTTGTGACATGGGCGCTTGCGCCATGCTGCCGCGTATCATC
GGACAGGGCCGCGCGGCGGAGCTGCTTTATATGGGTCGGTCGCTGGGCGCCGAGGAAGGCGAACGCTGGGGGTTTTTTAA
CCGGCTCGCGTCCGCTGAGGCGCTGGAAGCCGAAGCCATGAAGATGGCAGAGCGCATCGTTGAGGGGCCGACCTTTGCCA
ATGGCATGACCAAGACGATGCTGGCGCAAGAATGGTCCATGAGCCTTGAGCAGGCGATTGAGGCCGAGGCGCAGGCGCAG
GCGATCTGCATGCAGGGCAATGATTTCCGCCGCGCCTATGAGGCCTTCGTCGCGAAAGAGCGACCAGTGTTTGAAGGCGA
CTGA

Upstream 100 bases:

>100_bases
GATGGCGGGGCTTGGCGCAGATGAAATCACCGAAATGAGCGCGCTTCTGGACCAGATCCAGCCGGTTGCGGCGCCCCAAG
AAGACAAAGGATGACCCGAC

Downstream 100 bases:

>100_bases
GAGCGCCGAATTTCGCCTTCGGCGAGGATATTTGACAAGAAGATGAAGACAACGGGGAAGATAACGTGGCGGACCAGAGT
TTTCTGAATTGGCCCTTTTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSLDETTHFNCTIEGGIARISLNRPERKNPLTFESYAELRDWFRALPYSDEVHAVVIVPNGGNFSSGGDVHDIIGPLTRM
NMKELLAFTRMTGDLVKAMLNCSKPVISAVDGICAGAGAIIAMASDLRIATPEAKVAFLFNRVGLAGCDMGACAMLPRII
GQGRAAELLYMGRSLGAEEGERWGFFNRLASAEALEAEAMKMAERIVEGPTFANGMTKTMLAQEWSMSLEQAIEAEAQAQ
AICMQGNDFRRAYEAFVAKERPVFEGD

Sequences:

>Translated_267_residues
MSLDETTHFNCTIEGGIARISLNRPERKNPLTFESYAELRDWFRALPYSDEVHAVVIVPNGGNFSSGGDVHDIIGPLTRM
NMKELLAFTRMTGDLVKAMLNCSKPVISAVDGICAGAGAIIAMASDLRIATPEAKVAFLFNRVGLAGCDMGACAMLPRII
GQGRAAELLYMGRSLGAEEGERWGFFNRLASAEALEAEAMKMAERIVEGPTFANGMTKTMLAQEWSMSLEQAIEAEAQAQ
AICMQGNDFRRAYEAFVAKERPVFEGD
>Mature_266_residues
SLDETTHFNCTIEGGIARISLNRPERKNPLTFESYAELRDWFRALPYSDEVHAVVIVPNGGNFSSGGDVHDIIGPLTRMN
MKELLAFTRMTGDLVKAMLNCSKPVISAVDGICAGAGAIIAMASDLRIATPEAKVAFLFNRVGLAGCDMGACAMLPRIIG
QGRAAELLYMGRSLGAEEGERWGFFNRLASAEALEAEAMKMAERIVEGPTFANGMTKTMLAQEWSMSLEQAIEAEAQAQA
ICMQGNDFRRAYEAFVAKERPVFEGD

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=239, Percent_Identity=25.9414225941423, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI70995211, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI31542718, Length=252, Percent_Identity=23.4126984126984, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI68989263, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=31.3953488372093, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI221142681, Length=280, Percent_Identity=26.0714285714286, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788597, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787659, Length=248, Percent_Identity=24.1935483870968, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=22.8426395939086, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788682, Length=225, Percent_Identity=27.1111111111111, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560910, Length=197, Percent_Identity=28.4263959390863, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=257, Percent_Identity=27.2373540856031, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=253, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=25.9911894273128, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=25.6880733944954, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17535521, Length=263, Percent_Identity=24.3346007604563, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17554946, Length=253, Percent_Identity=25.6916996047431, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540306, Length=251, Percent_Identity=22.3107569721116, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920382, Length=265, Percent_Identity=26.7924528301887, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24653139, Length=257, Percent_Identity=26.0700389105058, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357171, Length=203, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24654903, Length=251, Percent_Identity=25.8964143426295, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129971, Length=247, Percent_Identity=24.6963562753036, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653477, Length=247, Percent_Identity=24.6963562753036, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650670, Length=194, Percent_Identity=25.2577319587629, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29057; Mature: 28926

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDETTHFNCTIEGGIARISLNRPERKNPLTFESYAELRDWFRALPYSDEVHAVVIVPN
CCCCCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GGNFSSGGDVHDIIGPLTRMNMKELLAFTRMTGDLVKAMLNCSKPVISAVDGICAGAGAI
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHH
IAMASDLRIATPEAKVAFLFNRVGLAGCDMGACAMLPRIIGQGRAAELLYMGRSLGAEEG
HEEECCCEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
ERWGFFNRLASAEALEAEAMKMAERIVEGPTFANGMTKTMLAQEWSMSLEQAIEAEAQAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AICMQGNDFRRAYEAFVAKERPVFEGD
HHEECCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLDETTHFNCTIEGGIARISLNRPERKNPLTFESYAELRDWFRALPYSDEVHAVVIVPN
CCCCCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GGNFSSGGDVHDIIGPLTRMNMKELLAFTRMTGDLVKAMLNCSKPVISAVDGICAGAGAI
CCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHH
IAMASDLRIATPEAKVAFLFNRVGLAGCDMGACAMLPRIIGQGRAAELLYMGRSLGAEEG
HEEECCCEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
ERWGFFNRLASAEALEAEAMKMAERIVEGPTFANGMTKTMLAQEWSMSLEQAIEAEAQAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AICMQGNDFRRAYEAFVAKERPVFEGD
HHEECCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]