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The map label for this gene is acdA [H]

Identifier: 99082079

GI number: 99082079

Start: 2352927

End: 2354081

Strand: Reverse

Name: acdA [H]

Synonym: TM1040_2239

Alternate gene names: 99082079

Gene position: 2354081-2352927 (Counterclockwise)

Preceding gene: 99082080

Following gene: 99082078

Centisome position: 73.54

GC content: 64.68

Gene sequence:

>1155_bases
GTGGCGGACCAGAGTTTTCTGAATTGGCCCTTTTTCGACGAAGAGCATCGAGCTTGGGCTGCCAAGGTCGAAGCTGTGGC
CGAGGGCCTTGAGGTGGATCACAGCGATACCGATGCGGCCTGTCGCAGGCTGGTGGCGGACCTTGGCGCGGCTGGGGTGT
TGCAGCCGACTGCGGCTGCGGGTGCCTCGAAGAGCCTCGATGTGCGCAAGCTGTGCCTAGCGCGTGAGATCCTCGCCCGC
CACGATGGGCTTGCGGATTTTGCCTTTGCCATGCAGGGGCTTGGCACAGGCGCGATTTCGCTGTTTGGAACCGACGCGCA
GAAAGCGGAGTGGCTGCCGAAAACCCGCAGCGGCGCGGCGATTGCTGCTTTTGCGCTGACGGAGCCGCAGTCGGGGTCGG
ATGTGGCGAACTCCACCATGACGGCGGTGCGCGATGGTGATGACTATGTGCTGAATGGTGAAAAGACCTGGATCTCCAAT
GGGGGGATCGCCGATGTCTACACGCTGTTTGCCCGCACCGGAGAGGCACCGGGCGCCAAGGGGCTCTCGGCCTTCATAGT
CACACCGGATCTGGACGGGTTTGAGGTGGTGGAGCGGCTCGAGACCATCGCACCGCACCCGCTGGCGACCTTGCGGTTCA
GCGATGTGCGCATCCCCGCAAGCGCCATGATCGGTGCGCCGGGGCAGGGGTTCCGTATCGCCATGTCGGTGCTGGATGTG
TTCCGCTCTACCGTGGCGGCGGCGGCGCTCGGCTTTGCGCGCCGGGCATTGGACGAGGCCTTGTGGCGTGTCACCGAGCG
TCATGTGCAGGGCGCGCCGCTCTTTGATTTGCAGATGGTGCAGGGGCATATCGCCGATATGGCGCTGGATGTGGATGCGG
CCGCGCTGCTGGTCTACCGCGCGGCCTGGACCAAGGACAGTGGTGCGGCGCGGGTCACGCGCGAGGCGGCAATGGCCAAG
CTGTTCTCGACCGAGGCGGCACAGGTCGTCATCGACAAGGCGGTGCAGCTCTTTGGGGGGGAGGGCGTGCGTTCGGGCGC
GATGGTTGAAAAACTCTATCGCGAAATCAGGGCGTTGCGCATCTATGAGGGCGCGAGCGACGTTCAGCGCGTGGTGATCG
CGCGGCAGGCGATGATGGCATTGGAGGGCAAATGA

Upstream 100 bases:

>100_bases
TCGCGAAAGAGCGACCAGTGTTTGAAGGCGACTGAGAGCGCCGAATTTCGCCTTCGGCGAGGATATTTGACAAGAAGATG
AAGACAACGGGGAAGATAAC

Downstream 100 bases:

>100_bases
TGACGCTCGGAGCATCCGCACATACCGATACATTCACCCGCGACGCCTTGCCGCCTGCGGATCAGTGGCCCGATTTTATG
CTTGAGGGGTTTGAGTATCC

Product: acyl-CoA dehydrogenase-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MADQSFLNWPFFDEEHRAWAAKVEAVAEGLEVDHSDTDAACRRLVADLGAAGVLQPTAAAGASKSLDVRKLCLAREILAR
HDGLADFAFAMQGLGTGAISLFGTDAQKAEWLPKTRSGAAIAAFALTEPQSGSDVANSTMTAVRDGDDYVLNGEKTWISN
GGIADVYTLFARTGEAPGAKGLSAFIVTPDLDGFEVVERLETIAPHPLATLRFSDVRIPASAMIGAPGQGFRIAMSVLDV
FRSTVAAAALGFARRALDEALWRVTERHVQGAPLFDLQMVQGHIADMALDVDAAALLVYRAAWTKDSGAARVTREAAMAK
LFSTEAAQVVIDKAVQLFGGEGVRSGAMVEKLYREIRALRIYEGASDVQRVVIARQAMMALEGK

Sequences:

>Translated_384_residues
MADQSFLNWPFFDEEHRAWAAKVEAVAEGLEVDHSDTDAACRRLVADLGAAGVLQPTAAAGASKSLDVRKLCLAREILAR
HDGLADFAFAMQGLGTGAISLFGTDAQKAEWLPKTRSGAAIAAFALTEPQSGSDVANSTMTAVRDGDDYVLNGEKTWISN
GGIADVYTLFARTGEAPGAKGLSAFIVTPDLDGFEVVERLETIAPHPLATLRFSDVRIPASAMIGAPGQGFRIAMSVLDV
FRSTVAAAALGFARRALDEALWRVTERHVQGAPLFDLQMVQGHIADMALDVDAAALLVYRAAWTKDSGAARVTREAAMAK
LFSTEAAQVVIDKAVQLFGGEGVRSGAMVEKLYREIRALRIYEGASDVQRVVIARQAMMALEGK
>Mature_383_residues
ADQSFLNWPFFDEEHRAWAAKVEAVAEGLEVDHSDTDAACRRLVADLGAAGVLQPTAAAGASKSLDVRKLCLAREILARH
DGLADFAFAMQGLGTGAISLFGTDAQKAEWLPKTRSGAAIAAFALTEPQSGSDVANSTMTAVRDGDDYVLNGEKTWISNG
GIADVYTLFARTGEAPGAKGLSAFIVTPDLDGFEVVERLETIAPHPLATLRFSDVRIPASAMIGAPGQGFRIAMSVLDVF
RSTVAAAALGFARRALDEALWRVTERHVQGAPLFDLQMVQGHIADMALDVDAAALLVYRAAWTKDSGAARVTREAAMAKL
FSTEAAQVVIDKAVQLFGGEGVRSGAMVEKLYREIRALRIYEGASDVQRVVIARQAMMALEGK

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=338, Percent_Identity=40.2366863905325, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI4557231, Length=314, Percent_Identity=37.5796178343949, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI187960098, Length=314, Percent_Identity=37.5796178343949, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI76496475, Length=350, Percent_Identity=35.7142857142857, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI4557235, Length=350, Percent_Identity=35.7142857142857, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI226958412, Length=370, Percent_Identity=32.7027027027027, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI226958414, Length=338, Percent_Identity=32.2485207100592, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI21361497, Length=295, Percent_Identity=35.2542372881356, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI7656849, Length=339, Percent_Identity=31.5634218289086, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4501859, Length=307, Percent_Identity=33.2247557003257, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI48976061, Length=294, Percent_Identity=34.3537414965986, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI211971008, Length=294, Percent_Identity=34.3537414965986, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4501857, Length=289, Percent_Identity=31.8339100346021, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI38505218, Length=317, Percent_Identity=29.0220820189274, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4503943, Length=355, Percent_Identity=26.4788732394366, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI7669494, Length=343, Percent_Identity=26.530612244898, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI87081958, Length=284, Percent_Identity=31.3380281690141, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1786223, Length=275, Percent_Identity=28, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082384, Length=290, Percent_Identity=28.6206896551724, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=287, Percent_Identity=39.7212543554007, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17569725, Length=287, Percent_Identity=36.9337979094077, Blast_Score=187, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=35.7142857142857, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17508101, Length=279, Percent_Identity=37.2759856630824, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17570075, Length=320, Percent_Identity=35.3125, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17506239, Length=337, Percent_Identity=33.5311572700297, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17533517, Length=280, Percent_Identity=33.2142857142857, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17538396, Length=336, Percent_Identity=29.7619047619048, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=225, Percent_Identity=37.7777777777778, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=297, Percent_Identity=34.6801346801347, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17505929, Length=337, Percent_Identity=27.5964391691395, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17551932, Length=337, Percent_Identity=27.5964391691395, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=30.8016877637131, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=345, Percent_Identity=26.6666666666667, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32563615, Length=181, Percent_Identity=31.4917127071823, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=308, Percent_Identity=29.8701298701299, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71982178, Length=211, Percent_Identity=31.2796208530806, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI86563381, Length=317, Percent_Identity=26.1829652996845, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=317, Percent_Identity=26.1829652996845, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540912, Length=300, Percent_Identity=28, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21356377, Length=337, Percent_Identity=37.9821958456973, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24646207, Length=318, Percent_Identity=37.4213836477987, Blast_Score=201, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24660351, Length=324, Percent_Identity=37.6543209876543, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI281363737, Length=352, Percent_Identity=33.5227272727273, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21355753, Length=355, Percent_Identity=31.830985915493, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24666513, Length=357, Percent_Identity=30.812324929972, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI19920834, Length=346, Percent_Identity=27.1676300578035, Blast_Score=101, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40927; Mature: 40796

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQSFLNWPFFDEEHRAWAAKVEAVAEGLEVDHSDTDAACRRLVADLGAAGVLQPTAAA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHC
GASKSLDVRKLCLAREILARHDGLADFAFAMQGLGTGAISLFGTDAQKAEWLPKTRSGAA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCE
IAAFALTEPQSGSDVANSTMTAVRDGDDYVLNGEKTWISNGGIADVYTLFARTGEAPGAK
EEEEEECCCCCCCHHHHHHHHHEECCCCEEECCCEEEECCCCHHHHHHHHHHCCCCCCCC
GLSAFIVTPDLDGFEVVERLETIAPHPLATLRFSDVRIPASAMIGAPGQGFRIAMSVLDV
CCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHH
FRSTVAAAALGFARRALDEALWRVTERHVQGAPLFDLQMVQGHIADMALDVDAAALLVYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
AAWTKDSGAARVTREAAMAKLFSTEAAQVVIDKAVQLFGGEGVRSGAMVEKLYREIRALR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IYEGASDVQRVVIARQAMMALEGK
HHCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADQSFLNWPFFDEEHRAWAAKVEAVAEGLEVDHSDTDAACRRLVADLGAAGVLQPTAAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHC
GASKSLDVRKLCLAREILARHDGLADFAFAMQGLGTGAISLFGTDAQKAEWLPKTRSGAA
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCE
IAAFALTEPQSGSDVANSTMTAVRDGDDYVLNGEKTWISNGGIADVYTLFARTGEAPGAK
EEEEEECCCCCCCHHHHHHHHHEECCCCEEECCCEEEECCCCHHHHHHHHHHCCCCCCCC
GLSAFIVTPDLDGFEVVERLETIAPHPLATLRFSDVRIPASAMIGAPGQGFRIAMSVLDV
CCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHH
FRSTVAAAALGFARRALDEALWRVTERHVQGAPLFDLQMVQGHIADMALDVDAAALLVYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
AAWTKDSGAARVTREAAMAKLFSTEAAQVVIDKAVQLFGGEGVRSGAMVEKLYREIRALR
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IYEGASDVQRVVIARQAMMALEGK
HHCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]