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The map label for this gene is glpX [H]

Identifier: 99082005

GI number: 99082005

Start: 2274543

End: 2275526

Strand: Direct

Name: glpX [H]

Synonym: TM1040_2165

Alternate gene names: 99082005

Gene position: 2274543-2275526 (Clockwise)

Preceding gene: 99082004

Following gene: 99082006

Centisome position: 71.06

GC content: 65.55

Gene sequence:

>984_bases
ATGACTTCGACCACCGCCGACGCGCCGTTTCACGACCGCCTGCTGTCCCTGGGCCTCGCCCGAGTTGCGGAACAGGCTGC
TCTGGCCTCTGCCCCGCTGATCGGACGCGGCGATGAAAAGGCCGCAGACCAAGCCGCCGTAAACGCGATGCGCGAACAGC
TGAACCTTCTGGACATCGCCGGTGTGGTGGTGATCGGCGAAGGCGAGCGCGACGAGGCGCCGATGCTCTATATCGGCGAG
GAAGTGGGCACCGGCAACGGCCCCGGCGTGGACATCGCGCTGGACCCGCTCGAAGGCACCACGCTCACCGCAAAGGACAT
GCCCAACGCGCTCACCGTGATCGCCATGGGTCCACGTGGCTCCATGCTGCATGCGCCCGACACCTATATGGACAAGCTGG
CCGTGGGTCCGGGCTACCCCGAGGGCGTGGTCTCTCTGGACATGTCGCCACGCGAACGCGTTGAGGCGCTGGCCAAGGCC
AAGGGCTGCACACCCGCGGACATCACTGTCTGCATCCTGGAACGTCCCCGCCATGAGGCGATGATCGCTGAGGTGCGCGA
AACCGGCGCGTCAATCCGCCTGATCACCGACGGCGATGTGGCGGGCGTCATGCATTGCGCAGAAGCAGAGGTCACAGGCA
TCGACATGTATATGGGCCAAGGCGGCGCGCCCGAAGGCGTGCTGGCGGCAGCGGCGCTCAAATGCATGGGCGGTCAGATC
TTTGGCCGTCTCTTGTTCCGCAACGACGACGAAAAAGCCCGCGCCGCCAAGGCCGGCATCACCGATCTGGACCGCGTCTA
TTCCCGCGACGAGATGGTGACACAGGATGTGATCTTTGCCGCTACCGGCGTCACCGGAGGCTCGCTGCTGCCGCGCATCA
AGCGTGAGCCGGGCTGGGTCGAGACCACCACACTGCTGATGCGCTCCAAGACCGGCTCGGTGCGCCGCATGAGCTATCGC
ACACCTCTGAGCGCGCATCAGTAA

Upstream 100 bases:

>100_bases
ATGTTGTTAGCGACATCAGCCGCGCTGCAGCCTTGCCCCCGTGGGGCTGGGCGGGCTATGCCGGGCGAGATCGCGCAAGT
TTGAGATAGGATTACTGGGA

Downstream 100 bases:

>100_bases
CCCAGAACAAACCTCAGCGCTTGCAGCGCGGAGCGGGATTTAGGTATTTGGGAAAAGATGAAGGCCGGGTCCCGCGCGGG
TCCGGCCTTTTTTACACAGA

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTSTTADAPFHDRLLSLGLARVAEQAALASAPLIGRGDEKAADQAAVNAMREQLNLLDIAGVVVIGEGERDEAPMLYIGE
EVGTGNGPGVDIALDPLEGTTLTAKDMPNALTVIAMGPRGSMLHAPDTYMDKLAVGPGYPEGVVSLDMSPRERVEALAKA
KGCTPADITVCILERPRHEAMIAEVRETGASIRLITDGDVAGVMHCAEAEVTGIDMYMGQGGAPEGVLAAAALKCMGGQI
FGRLLFRNDDEKARAAKAGITDLDRVYSRDEMVTQDVIFAATGVTGGSLLPRIKREPGWVETTTLLMRSKTGSVRRMSYR
TPLSAHQ

Sequences:

>Translated_327_residues
MTSTTADAPFHDRLLSLGLARVAEQAALASAPLIGRGDEKAADQAAVNAMREQLNLLDIAGVVVIGEGERDEAPMLYIGE
EVGTGNGPGVDIALDPLEGTTLTAKDMPNALTVIAMGPRGSMLHAPDTYMDKLAVGPGYPEGVVSLDMSPRERVEALAKA
KGCTPADITVCILERPRHEAMIAEVRETGASIRLITDGDVAGVMHCAEAEVTGIDMYMGQGGAPEGVLAAAALKCMGGQI
FGRLLFRNDDEKARAAKAGITDLDRVYSRDEMVTQDVIFAATGVTGGSLLPRIKREPGWVETTTLLMRSKTGSVRRMSYR
TPLSAHQ
>Mature_326_residues
TSTTADAPFHDRLLSLGLARVAEQAALASAPLIGRGDEKAADQAAVNAMREQLNLLDIAGVVVIGEGERDEAPMLYIGEE
VGTGNGPGVDIALDPLEGTTLTAKDMPNALTVIAMGPRGSMLHAPDTYMDKLAVGPGYPEGVVSLDMSPRERVEALAKAK
GCTPADITVCILERPRHEAMIAEVRETGASIRLITDGDVAGVMHCAEAEVTGIDMYMGQGGAPEGVLAAAALKCMGGQIF
GRLLFRNDDEKARAAKAGITDLDRVYSRDEMVTQDVIFAATGVTGGSLLPRIKREPGWVETTTLLMRSKTGSVRRMSYRT
PLSAHQ

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=322, Percent_Identity=46.2732919254658, Blast_Score=246, Evalue=1e-66,
Organism=Escherichia coli, GI1789298, Length=308, Percent_Identity=43.5064935064935, Blast_Score=211, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 34559; Mature: 34428

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTTADAPFHDRLLSLGLARVAEQAALASAPLIGRGDEKAADQAAVNAMREQLNLLDIA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEE
GVVVIGEGERDEAPMLYIGEEVGTGNGPGVDIALDPLEGTTLTAKDMPNALTVIAMGPRG
EEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCEEECCCCCCEEEEEEECCCC
SMLHAPDTYMDKLAVGPGYPEGVVSLDMSPRERVEALAKAKGCTPADITVCILERPRHEA
CEEECCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
MIAEVRETGASIRLITDGDVAGVMHCAEAEVTGIDMYMGQGGAPEGVLAAAALKCMGGQI
HHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCHHH
FGRLLFRNDDEKARAAKAGITDLDRVYSRDEMVTQDVIFAATGVTGGSLLPRIKREPGWV
HHHHEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHCCCCCCE
ETTTLLMRSKTGSVRRMSYRTPLSAHQ
EHHHEEEECCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
TSTTADAPFHDRLLSLGLARVAEQAALASAPLIGRGDEKAADQAAVNAMREQLNLLDIA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEE
GVVVIGEGERDEAPMLYIGEEVGTGNGPGVDIALDPLEGTTLTAKDMPNALTVIAMGPRG
EEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCEEECCCCCCEEEEEEECCCC
SMLHAPDTYMDKLAVGPGYPEGVVSLDMSPRERVEALAKAKGCTPADITVCILERPRHEA
CEEECCHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHH
MIAEVRETGASIRLITDGDVAGVMHCAEAEVTGIDMYMGQGGAPEGVLAAAALKCMGGQI
HHHHHHHCCCEEEEEECCCHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCHHH
FGRLLFRNDDEKARAAKAGITDLDRVYSRDEMVTQDVIFAATGVTGGSLLPRIKREPGWV
HHHHEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHCCCCCCE
ETTTLLMRSKTGSVRRMSYRTPLSAHQ
EHHHEEEECCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]