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The map label for this gene is atpD2 [H]

Identifier: 99081926

GI number: 99081926

Start: 2189250

End: 2190674

Strand: Reverse

Name: atpD2 [H]

Synonym: TM1040_2086

Alternate gene names: 99081926

Gene position: 2190674-2189250 (Counterclockwise)

Preceding gene: 99081927

Following gene: 99081925

Centisome position: 68.44

GC content: 60.0

Gene sequence:

>1425_bases
ATGGCAAATGCAAAAGGCAAGGTGACTCAGATCATCGGCGCCGTTGTGGACGTCCAGTTCGACGGCGAGCTGCCGGCGAT
TTTGAACGCCCTCACCACCGACAACAACGGCAAGAAACTCGTTCTCGAGGTTGCTCAGCACCTCGGCGAGAACTCTGTCC
GTACCATCGCGATGGACGCGACCGAAGGTCTCGTGCGTGGTCAGGAAGTGACCGACACCGGTGCTCCGATCTCGATTCCG
GTCGGCAACGCAACCCTGGGCCGCATCCTGAACGTTGTGGGTGAGCCGGTTGACGAAGGCGAGCCGATCGTTGCGAAAGA
GACCCGCGCGATCCACCAGCCCGCGCCCGAGTTCAACGACCAGTCCACCGAATCCGAGGTCCTCGTGACCGGCATCAAGG
TGATCGACCTTCTCGCGCCTTATGCGAAGGGTGGTAAGATCGGTCTGTTCGGCGGCGCCGGCGTTGGTAAAACCGTTCTC
ATCATGGAACTGATCAACAACATCGCAAAAGTGCACTCGGGTTACTCCGTGTTCGCGGGTGTTGGCGAACGGACCCGTGA
AGGCAACGACCTTTACCACGAGATGATCGAATCCAACGTGATTAAGCCCGACAACCTCGAAGAGTCGCAGGTTGCTCTGG
TTTACGGCCAGATGAACGAGCCTCCGGGTGCGCGTGCCCGTGTTGCCCTGACCGGTCTGACCCTTGCAGAGCAGTTCCGT
GACCAGTCCGGTACCGACGTTCTGTTCTTCGTGGACAACATCTTCCGCTTCACGCAGGCCGGTTCCGAGGTGTCCGCACT
TCTCGGCCGTATCCCCTCCGCTGTGGGCTACCAGCCGACGCTGGCGACCGACATGGGTGCGATGCAGGAGCGTATTACCT
CCACCAAGAACGGCTCGATCACCTCGATCCAGGCTGTGTATGTTCCCGCGGACGACCTTACCGACCCGGCACCTGCAACA
ACCTTTGCCCACTTGGACGCGACCACCGTTCTCAACCGTGCGATCTCCGAGCTCGGCATCTACCCCGCTGTGGACCCGCT
CGACTCCTCGTCGCGCCTGATGGACCCGCAGATCGTTGGCGAAGAGCACTACAAAGTGGCCTCCGACGTTCAGCAGATCC
TTCAGCGCTACAAGTCGCTGCAGGACATCATCGCGATCCTCGGCATGGACGAACTCTCCGAAGAGGATAAGCTGACCGTT
GCGCGTGCGCGTAAGATCCAGCGCTTCCTGTCGCAGCCGTTCGACGTTGCAAAAGTCTTCACCGGTTCCGACGGTGTGCA
GGTTTCCCTCGAGGACACCATCGCGTCGTTCAAAGCCGTTGTGGCTGGCGAATACGACCACCTTCCCGAAGGCGCCTTCT
ACATGGTTGGCGGCATCGACGAAGTGATCGCAAAAGCCGAGAAAATGGCTGCTGACGCGGCCTAA

Upstream 100 bases:

>100_bases
CCATCGAGTACAACCGCTCGCGTCAGGCCGTCATCACCAACGAGCTTATTGAAATCATTTCGGGCGCCGAGGCGCTCTAA
GAGACAACCGGAGACGAAAC

Downstream 100 bases:

>100_bases
GGAGGGCCCTCATGGCTGATACGATGCAATTCGATCTCGTGAGCCCGGAGCGGAGCCTTGCTTCGCTTCAGGCCCGCGCG
GTCCAGATCCCCGGTGCTGA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 2; F-ATPase subunit beta 2 [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MANAKGKVTQIIGAVVDVQFDGELPAILNALTTDNNGKKLVLEVAQHLGENSVRTIAMDATEGLVRGQEVTDTGAPISIP
VGNATLGRILNVVGEPVDEGEPIVAKETRAIHQPAPEFNDQSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVL
IMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFR
DQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSITSIQAVYVPADDLTDPAPAT
TFAHLDATTVLNRAISELGIYPAVDPLDSSSRLMDPQIVGEEHYKVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTV
ARARKIQRFLSQPFDVAKVFTGSDGVQVSLEDTIASFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA

Sequences:

>Translated_474_residues
MANAKGKVTQIIGAVVDVQFDGELPAILNALTTDNNGKKLVLEVAQHLGENSVRTIAMDATEGLVRGQEVTDTGAPISIP
VGNATLGRILNVVGEPVDEGEPIVAKETRAIHQPAPEFNDQSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVL
IMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFR
DQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSITSIQAVYVPADDLTDPAPAT
TFAHLDATTVLNRAISELGIYPAVDPLDSSSRLMDPQIVGEEHYKVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTV
ARARKIQRFLSQPFDVAKVFTGSDGVQVSLEDTIASFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
>Mature_473_residues
ANAKGKVTQIIGAVVDVQFDGELPAILNALTTDNNGKKLVLEVAQHLGENSVRTIAMDATEGLVRGQEVTDTGAPISIPV
GNATLGRILNVVGEPVDEGEPIVAKETRAIHQPAPEFNDQSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLI
MELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFRD
QSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSITSIQAVYVPADDLTDPAPATT
FAHLDATTVLNRAISELGIYPAVDPLDSSSRLMDPQIVGEEHYKVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTVA
RARKIQRFLSQPFDVAKVFTGSDGVQVSLEDTIASFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=471, Percent_Identity=77.7070063694268, Blast_Score=738, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=337, Percent_Identity=28.7833827893175, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913428, Length=374, Percent_Identity=28.0748663101604, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI19913426, Length=404, Percent_Identity=26.4851485148515, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI50345984, Length=298, Percent_Identity=24.1610738255034, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI4757810, Length=298, Percent_Identity=24.1610738255034, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1790170, Length=467, Percent_Identity=68.9507494646681, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=395, Percent_Identity=29.620253164557, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790172, Length=436, Percent_Identity=22.9357798165138, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144756, Length=469, Percent_Identity=75.6929637526652, Blast_Score=725, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=309, Percent_Identity=30.0970873786408, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=355, Percent_Identity=27.6056338028169, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=390, Percent_Identity=26.4102564102564, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=321, Percent_Identity=22.1183800623053, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71988063, Length=321, Percent_Identity=22.1183800623053, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=460, Percent_Identity=76.5217391304348, Blast_Score=708, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=374, Percent_Identity=28.8770053475936, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319370, Length=372, Percent_Identity=24.4623655913978, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320016, Length=218, Percent_Identity=26.605504587156, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24638766, Length=469, Percent_Identity=78.4648187633262, Blast_Score=744, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=468, Percent_Identity=71.3675213675214, Blast_Score=667, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=91, Percent_Identity=72.5274725274725, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24583992, Length=379, Percent_Identity=28.4960422163588, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24583988, Length=363, Percent_Identity=28.9256198347107, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583986, Length=363, Percent_Identity=28.9256198347107, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583984, Length=363, Percent_Identity=28.9256198347107, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI20129479, Length=313, Percent_Identity=27.7955271565495, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281361666, Length=360, Percent_Identity=28.8888888888889, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646341, Length=360, Percent_Identity=28.8888888888889, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136796, Length=360, Percent_Identity=28.8888888888889, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658560, Length=299, Percent_Identity=23.0769230769231, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50581; Mature: 50450

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAKGKVTQIIGAVVDVQFDGELPAILNALTTDNNGKKLVLEVAQHLGENSVRTIAMDA
CCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEC
TEGLVRGQEVTDTGAPISIPVGNATLGRILNVVGEPVDEGEPIVAKETRAIHQPAPEFND
HHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCCC
QSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGYSVFAG
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEC
VGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHC
DQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSI
CCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCE
TSIQAVYVPADDLTDPAPATTFAHLDATTVLNRAISELGIYPAVDPLDSSSRLMDPQIVG
EEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCC
EEHYKVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEE
TGSDGVQVSLEDTIASFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
ECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANAKGKVTQIIGAVVDVQFDGELPAILNALTTDNNGKKLVLEVAQHLGENSVRTIAMDA
CCCCHHHHHHHHHHEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEEEC
TEGLVRGQEVTDTGAPISIPVGNATLGRILNVVGEPVDEGEPIVAKETRAIHQPAPEFND
HHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCCC
QSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGYSVFAG
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEC
VGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEHHHHHHHHHC
DQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSI
CCCCCEEEEHHHHHHHHHHCCHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHCCCCCCE
TSIQAVYVPADDLTDPAPATTFAHLDATTVLNRAISELGIYPAVDPLDSSSRLMDPQIVG
EEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCC
EEHYKVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHCCCCCCHHEE
TGSDGVQVSLEDTIASFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
ECCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA