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The map label for this gene is atpC

Identifier: 99081925

GI number: 99081925

Start: 2188825

End: 2189238

Strand: Reverse

Name: atpC

Synonym: TM1040_2085

Alternate gene names: 99081925

Gene position: 2189238-2188825 (Counterclockwise)

Preceding gene: 99081926

Following gene: 99081924

Centisome position: 68.39

GC content: 63.53

Gene sequence:

>414_bases
ATGGCTGATACGATGCAATTCGATCTCGTGAGCCCGGAGCGGAGCCTTGCTTCGCTTCAGGCCCGCGCGGTCCAGATCCC
CGGTGCTGAGGGTGACATGACGGCGATGCCTTTGCACGCGCCGACACTGACCACCCTGCGTCCGGGCATCCTGAAGGTGG
ACGCACCGGAAGGCACAACGGAGTATCTCGTCACTGGCGGGTTTGCCCAGATCACTGCCGAGGGCCTGTCGGTCCTCGCG
GAGCGGGCGATCCCCATGGACGAGATGACCCGCGCCCATCTGGACGAGCTCATCGAGGAAGCCCGCACCATGTACAAGAC
CGCGCAGGAGGACAACTCTGAGCATGGTCTGGTGGAAGACGCGGCCAAGATGCTTGCAGACATGGAAGCGCTCGGGACCC
ACATGAGCCTCTGA

Upstream 100 bases:

>100_bases
ACCACCTTCCCGAAGGCGCCTTCTACATGGTTGGCGGCATCGACGAAGTGATCGCAAAAGCCGAGAAAATGGCTGCTGAC
GCGGCCTAAGGAGGGCCCTC

Downstream 100 bases:

>100_bases
TCCTCCGGGAACAGATGAAACCTATAGAAACCGGCCCGCAGATCTGCGGGCCGGTTTTCTTTTTGTTAAGCATCATTTTG
ATATGAGTAATTTTAGATGT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MADTMQFDLVSPERSLASLQARAVQIPGAEGDMTAMPLHAPTLTTLRPGILKVDAPEGTTEYLVTGGFAQITAEGLSVLA
ERAIPMDEMTRAHLDELIEEARTMYKTAQEDNSEHGLVEDAAKMLADMEALGTHMSL

Sequences:

>Translated_137_residues
MADTMQFDLVSPERSLASLQARAVQIPGAEGDMTAMPLHAPTLTTLRPGILKVDAPEGTTEYLVTGGFAQITAEGLSVLA
ERAIPMDEMTRAHLDELIEEARTMYKTAQEDNSEHGLVEDAAKMLADMEALGTHMSL
>Mature_136_residues
ADTMQFDLVSPERSLASLQARAVQIPGAEGDMTAMPLHAPTLTTLRPGILKVDAPEGTTEYLVTGGFAQITAEGLSVLAE
RAIPMDEMTRAHLDELIEEARTMYKTAQEDNSEHGLVEDAAKMLADMEALGTHMSL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=125, Percent_Identity=31.2, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_SILST (Q1GEU9)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_614079.1
- ProteinModelPortal:   Q1GEU9
- STRING:   Q1GEU9
- GeneID:   4077836
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_2085
- NMPDR:   fig|292414.1.peg.454
- eggNOG:   COG0355
- HOGENOM:   HBG663981
- OMA:   HAPTMTT
- PhylomeDB:   Q1GEU9
- ProtClustDB:   PRK13443
- BioCyc:   SSP292414:TM1040_2085-MONOMER
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020546
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF02823 ATP-synt_DE_N; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 14771; Mature: 14640

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.6 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTMQFDLVSPERSLASLQARAVQIPGAEGDMTAMPLHAPTLTTLRPGILKVDAPEGTT
CCCCCEEECCCCHHHHHHHHHHHEECCCCCCCCEECCCCCCCHHHCCCCEEEEECCCCCC
EYLVTGGFAQITAEGLSVLAERAIPMDEMTRAHLDELIEEARTMYKTAQEDNSEHGLVED
CEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AAKMLADMEALGTHMSL
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADTMQFDLVSPERSLASLQARAVQIPGAEGDMTAMPLHAPTLTTLRPGILKVDAPEGTT
CCCCEEECCCCHHHHHHHHHHHEECCCCCCCCEECCCCCCCHHHCCCCEEEEECCCCCC
EYLVTGGFAQITAEGLSVLAERAIPMDEMTRAHLDELIEEARTMYKTAQEDNSEHGLVED
CEEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
AAKMLADMEALGTHMSL
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA