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The map label for this gene is yfhC [C]

Identifier: 99081767

GI number: 99081767

Start: 2025549

End: 2025983

Strand: Reverse

Name: yfhC [C]

Synonym: TM1040_1926

Alternate gene names: 99081767

Gene position: 2025983-2025549 (Counterclockwise)

Preceding gene: 99081772

Following gene: 99081766

Centisome position: 63.29

GC content: 67.13

Gene sequence:

>435_bases
ATGGCAGAGGCGCTCGACGAGGCGCGCGCAGCGGCCGCGCGTGGCGAAGTGCCCGTAGGCGCGGTGCTGGTGAGCCCAGA
GGGCAAGGTCGTCGCGCGGGCGGGAAATCGCACCCGGGAACTCAATGATCCGACGGCCCATGCCGAGGTGCTGGCGATCC
GCGCCGCCTGCGCCGCACTGGGGAGCGAGCGGCTCTTGGGGCATGATCTTTACGTGACGCTGGAGCCCTGTGCCATGTGT
GCGGCTGCCATTGCAGCGGCCCGCATCGCGCGCGTTTATTACGGTGCCTCTGATCCGAAATCTGGCGGAGTTGCCCATGG
CGCTTGTGTGTTCGACCATCCGCAGTCCCATCATGCGCCCGAGGTCTATGAGGGCTTCTCGGCGGCCCAATCCGAGGCGC
TGTTGCGCGCGTTCTTTGCGCTACGCCGCAAATGA

Upstream 100 bases:

>100_bases
CAGCCGCACGGACGTCCCGCGATGATGGGGCCGGAGCGTGCCAACGGGCATTGGAACGGGCGACAAAAGGAGCAACGCAG
AGGTGGAGTTTCGATCCTTC

Downstream 100 bases:

>100_bases
GGCCGCCGCCCGAGGCGCTCTTGCGGCGCTTTGATCTCAGAGATCCTGATTGGGTTGCGGGCACCCGGCACGCGCAGGTC
TGGAAGGTGCGGTTGCGCTC

Product: CMP/dCMP deaminase, zinc-binding

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MAEALDEARAAAARGEVPVGAVLVSPEGKVVARAGNRTRELNDPTAHAEVLAIRAACAALGSERLLGHDLYVTLEPCAMC
AAAIAAARIARVYYGASDPKSGGVAHGACVFDHPQSHHAPEVYEGFSAAQSEALLRAFFALRRK

Sequences:

>Translated_144_residues
MAEALDEARAAAARGEVPVGAVLVSPEGKVVARAGNRTRELNDPTAHAEVLAIRAACAALGSERLLGHDLYVTLEPCAMC
AAAIAAARIARVYYGASDPKSGGVAHGACVFDHPQSHHAPEVYEGFSAAQSEALLRAFFALRRK
>Mature_143_residues
AEALDEARAAAARGEVPVGAVLVSPEGKVVARAGNRTRELNDPTAHAEVLAIRAACAALGSERLLGHDLYVTLEPCAMCA
AAIAAARIARVYYGASDPKSGGVAHGACVFDHPQSHHAPEVYEGFSAAQSEALLRAFFALRRK

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=147, Percent_Identity=32.6530612244898, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=44.4444444444444, Blast_Score=115, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17555996, Length=101, Percent_Identity=46.5346534653465, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17541138, Length=142, Percent_Identity=34.5070422535211, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554608, Length=108, Percent_Identity=37.962962962963, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=153, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=38.7755102040816, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 15020; Mature: 14889

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEALDEARAAAARGEVPVGAVLVSPEGKVVARAGNRTRELNDPTAHAEVLAIRAACAAL
CCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
GSERLLGHDLYVTLEPCAMCAAAIAAARIARVYYGASDPKSGGVAHGACVFDHPQSHHAP
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCC
EVYEGFSAAQSEALLRAFFALRRK
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEALDEARAAAARGEVPVGAVLVSPEGKVVARAGNRTRELNDPTAHAEVLAIRAACAAL
CCHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
GSERLLGHDLYVTLEPCAMCAAAIAAARIARVYYGASDPKSGGVAHGACVFDHPQSHHAP
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCC
EVYEGFSAAQSEALLRAFFALRRK
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA