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The map label for this gene is tag [H]

Identifier: 99081763

GI number: 99081763

Start: 2023619

End: 2024221

Strand: Reverse

Name: tag [H]

Synonym: TM1040_1922

Alternate gene names: 99081763

Gene position: 2024221-2023619 (Counterclockwise)

Preceding gene: 99081764

Following gene: 99081760

Centisome position: 63.24

GC content: 61.69

Gene sequence:

>603_bases
ATGAGCCGCGTTGTTACAGGCGGGGATGGCCGCACGCGCTGCGCCTGGTCTGCCTCGGCCCCGGAGTTTGACGCCTACCA
TGACACAGAGTGGGGTTTCCCCGTGGGGGATGACCGGCGGCTCTTTGAAAAGATCTGCCTTGAGAGTTTCCAATCTGGGC
TGAGCTGGCGCACGATCCTAGCCAAGCGCGAGAATTTTCGCGCTGCCTTTGATGGTTTCGACTATCACGCGATGGCGGCC
TACGGACCTGAAAAGGTCGCGGCGCTGCTGCAAGATGCGGGGATCATTCGTCATCGCGGCAAGATCGAGGCGGTGATCAA
CAACGCAGCGCGTGCGGTGGAGATGGAGCAAAGCGAGGGCGCGCTCGCGGCGTTTTTCTGGCGTTACGAGGTGGAGACCC
CACCCGAGCCGCAGACGGTCTCGACCTGTCCTGAATCGGTGGCCCTGTCAAAAGAGCTGAAGACGCGCGGCTGGAAATTT
GTCGGACCTACGACCTGTTTTGCCTTCATGCAGGCCATGGGGCTGGTGAATGACCACGCGGAGGGCTGCTATTGCCGCCC
GATCGCGGCCGCAGCTCGTCAGGGTTTTGCCAAACCGGTCTGA

Upstream 100 bases:

>100_bases
CGACAGATCCTTTTGTGCGCGACGGGCTGGTTGCGGTGGATATCACCGCCTTCACCCCCTCTCAGGCGGATCCGCGGCTT
TCATTCCTCAAGGTGGCGGC

Downstream 100 bases:

>100_bases
TCAGCACGCCGAACTCCTGCGGTTTGAAGCCAAGGGATTAGAGACACGTCGAGGGTGTCATTTGAGGGTGTCGCTTTGTG
CTGTGCCCAAAGCGACCCGC

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSRVVTGGDGRTRCAWSASAPEFDAYHDTEWGFPVGDDRRLFEKICLESFQSGLSWRTILAKRENFRAAFDGFDYHAMAA
YGPEKVAALLQDAGIIRHRGKIEAVINNAARAVEMEQSEGALAAFFWRYEVETPPEPQTVSTCPESVALSKELKTRGWKF
VGPTTCFAFMQAMGLVNDHAEGCYCRPIAAAARQGFAKPV

Sequences:

>Translated_200_residues
MSRVVTGGDGRTRCAWSASAPEFDAYHDTEWGFPVGDDRRLFEKICLESFQSGLSWRTILAKRENFRAAFDGFDYHAMAA
YGPEKVAALLQDAGIIRHRGKIEAVINNAARAVEMEQSEGALAAFFWRYEVETPPEPQTVSTCPESVALSKELKTRGWKF
VGPTTCFAFMQAMGLVNDHAEGCYCRPIAAAARQGFAKPV
>Mature_199_residues
SRVVTGGDGRTRCAWSASAPEFDAYHDTEWGFPVGDDRRLFEKICLESFQSGLSWRTILAKRENFRAAFDGFDYHAMAAY
GPEKVAALLQDAGIIRHRGKIEAVINNAARAVEMEQSEGALAAFFWRYEVETPPEPQTVSTCPESVALSKELKTRGWKFV
GPTTCFAFMQAMGLVNDHAEGCYCRPIAAAARQGFAKPV

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=181, Percent_Identity=53.0386740331492, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 22137; Mature: 22006

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVVTGGDGRTRCAWSASAPEFDAYHDTEWGFPVGDDRRLFEKICLESFQSGLSWRTIL
CCCEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
AKRENFRAAFDGFDYHAMAAYGPEKVAALLQDAGIIRHRGKIEAVINNAARAVEMEQSEG
HHHHCCHHHHCCCCCEEHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
ALAAFFWRYEVETPPEPQTVSTCPESVALSKELKTRGWKFVGPTTCFAFMQAMGLVNDHA
CEEEEEEEEECCCCCCCCHHHHCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCCCC
EGCYCRPIAAAARQGFAKPV
CCEEECHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRVVTGGDGRTRCAWSASAPEFDAYHDTEWGFPVGDDRRLFEKICLESFQSGLSWRTIL
CCEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHH
AKRENFRAAFDGFDYHAMAAYGPEKVAALLQDAGIIRHRGKIEAVINNAARAVEMEQSEG
HHHHCCHHHHCCCCCEEHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
ALAAFFWRYEVETPPEPQTVSTCPESVALSKELKTRGWKFVGPTTCFAFMQAMGLVNDHA
CEEEEEEEEECCCCCCCCHHHHCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCCCC
EGCYCRPIAAAARQGFAKPV
CCEEECHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]