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The map label for this gene is nahR [H]

Identifier: 99081592

GI number: 99081592

Start: 1843922

End: 1844821

Strand: Direct

Name: nahR [H]

Synonym: TM1040_1751

Alternate gene names: 99081592

Gene position: 1843922-1844821 (Clockwise)

Preceding gene: 99081590

Following gene: 99081593

Centisome position: 57.61

GC content: 62.44

Gene sequence:

>900_bases
ATGACTGTTGATATATCGCTCCTTCGCGTCTTCCACGCCGTTATGGAAGAGCGCAATGTCACTGCCGCTGCGCGCCGTCT
GGGACAATCACAAAGCACGGTCAGTGCAGCGCTCGCACGGTTGCGGGATGCGTTGGGCGATGAGTTGTTCCTGCGCGCAC
GCTATGGTGTTGAGCCAACTGAAAAAGCGCTACAGATCGCGCCCGACATCGCCGCCGGCCTCGATCGACTCGAACAGGCG
TTTCGCGCTGCAGAACCCTTTGACCCCATTCGCAGCACCCGGCGTTTCCGGTTACTGCTGGGCCCTTACGCCGAAGTGGT
GCTGGCGCCGGATCTGGCCGAAGCCTTTGCTCAGCACGCCCCCAAAGCCCAGCTTGAGCTTGCGCCGATCGGTCCTGACC
TAGATCCACGCAAGCTCGCCGCCCAAAGCTTTGACCTCGCCATTGGCCGCTTTGCACCGCCCCCCGACGATCTTGTGGTC
TCGGATCTCTTTAGTGACGGGTTTCGCTGCATCGTCGCCCCAGCCGCTCTGCCCGAGGGCGCCAGTCTGGATCTCGATCT
CTATGAGACCCTGCCCCATGTGATCGTCGCGCCCCCCGGCAGATGGCGGACAGGAGTGCATAAGTTGACCGCTGCCAGCG
GCTTGCAGCGCAATACAGCCGTGGCAGTGTCGCATTTTCTGACGGCCGCCCCGACCGTGGCCCGTATCAACGGGATCGCC
ACTGTCCCTGCCCGCATCGCCGCCATGGTCGCGGCACCTTATGGGCTGCGCAATGTTGCAGTGCCGCGCGATCTTGGGAC
TTTTCCAACCCAGATCGCCTGGCACCCGCACCAGCGCAGAGATCCCCGTCATGTCTGGCTGAGAGACCTACTTTTGTCTC
TCACCGCGACAAGCACCTGA

Upstream 100 bases:

>100_bases
CCCCAGGAGGAGTGTGCGGGGCGCGTCTCACCTCATATAAGCAGGATCAGAAGATCGAGAAATTGATGCATACCATGACA
GAAATCGATATTCTGGACAT

Downstream 100 bases:

>100_bases
TTTTTCGGAGCTTTCAGCCCCACCACGGTCTTATGGCCGCCTTTATGCCACGCCTTTTTGGGAGCCCCATCAAAGTCGCC
AGCGCAATCGCTTCGCCGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTVDISLLRVFHAVMEERNVTAAARRLGQSQSTVSAALARLRDALGDELFLRARYGVEPTEKALQIAPDIAAGLDRLEQA
FRAAEPFDPIRSTRRFRLLLGPYAEVVLAPDLAEAFAQHAPKAQLELAPIGPDLDPRKLAAQSFDLAIGRFAPPPDDLVV
SDLFSDGFRCIVAPAALPEGASLDLDLYETLPHVIVAPPGRWRTGVHKLTAASGLQRNTAVAVSHFLTAAPTVARINGIA
TVPARIAAMVAAPYGLRNVAVPRDLGTFPTQIAWHPHQRRDPRHVWLRDLLLSLTATST

Sequences:

>Translated_299_residues
MTVDISLLRVFHAVMEERNVTAAARRLGQSQSTVSAALARLRDALGDELFLRARYGVEPTEKALQIAPDIAAGLDRLEQA
FRAAEPFDPIRSTRRFRLLLGPYAEVVLAPDLAEAFAQHAPKAQLELAPIGPDLDPRKLAAQSFDLAIGRFAPPPDDLVV
SDLFSDGFRCIVAPAALPEGASLDLDLYETLPHVIVAPPGRWRTGVHKLTAASGLQRNTAVAVSHFLTAAPTVARINGIA
TVPARIAAMVAAPYGLRNVAVPRDLGTFPTQIAWHPHQRRDPRHVWLRDLLLSLTATST
>Mature_298_residues
TVDISLLRVFHAVMEERNVTAAARRLGQSQSTVSAALARLRDALGDELFLRARYGVEPTEKALQIAPDIAAGLDRLEQAF
RAAEPFDPIRSTRRFRLLLGPYAEVVLAPDLAEAFAQHAPKAQLELAPIGPDLDPRKLAAQSFDLAIGRFAPPPDDLVVS
DLFSDGFRCIVAPAALPEGASLDLDLYETLPHVIVAPPGRWRTGVHKLTAASGLQRNTAVAVSHFLTAAPTVARINGIAT
VPARIAAMVAAPYGLRNVAVPRDLGTFPTQIAWHPHQRRDPRHVWLRDLLLSLTATST

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=27.1186440677966, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081766, Length=282, Percent_Identity=22.6950354609929, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789204, Length=173, Percent_Identity=28.9017341040462, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32406; Mature: 32274

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDISLLRVFHAVMEERNVTAAARRLGQSQSTVSAALARLRDALGDELFLRARYGVEPT
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHEEEHHHCCCCHH
EKALQIAPDIAAGLDRLEQAFRAAEPFDPIRSTRRFRLLLGPYAEVVLAPDLAEAFAQHA
HHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCHHHHEECCHHHHHHHHHC
PKAQLELAPIGPDLDPRKLAAQSFDLAIGRFAPPPDDLVVSDLFSDGFRCIVAPAALPEG
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
ASLDLDLYETLPHVIVAPPGRWRTGVHKLTAASGLQRNTAVAVSHFLTAAPTVARINGIA
CCCCCHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCH
TVPARIAAMVAAPYGLRNVAVPRDLGTFPTQIAWHPHQRRDPRHVWLRDLLLSLTATST
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVDISLLRVFHAVMEERNVTAAARRLGQSQSTVSAALARLRDALGDELFLRARYGVEPT
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHEEEHHHCCCCHH
EKALQIAPDIAAGLDRLEQAFRAAEPFDPIRSTRRFRLLLGPYAEVVLAPDLAEAFAQHA
HHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCHHHHEECCHHHHHHHHHC
PKAQLELAPIGPDLDPRKLAAQSFDLAIGRFAPPPDDLVVSDLFSDGFRCIVAPAALPEG
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
ASLDLDLYETLPHVIVAPPGRWRTGVHKLTAASGLQRNTAVAVSHFLTAAPTVARINGIA
CCCCCHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCH
TVPARIAAMVAAPYGLRNVAVPRDLGTFPTQIAWHPHQRRDPRHVWLRDLLLSLTATST
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]