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The map label for this gene is selD [H]

Identifier: 99081385

GI number: 99081385

Start: 1650329

End: 1652491

Strand: Direct

Name: selD [H]

Synonym: TM1040_1544

Alternate gene names: 99081385

Gene position: 1650329-1652491 (Clockwise)

Preceding gene: 99081384

Following gene: 99081387

Centisome position: 51.56

GC content: 63.25

Gene sequence:

>2163_bases
ATGCACGCTCCCCGCCTTCCCCTGACCCGCGATCTGGTTCTTGTGGGAGGCGGACACACCCATGCGCTTTTGCTCCGGAT
GTGGGGCATGAAGCCGCTTCCCGGCGTGCGACTAACGCTGATCAATCCCGGACCAACCGCGCCCTATTCAGGGATGCTGC
CGGGGTTTGTCGCCGGTCACTACACGCGGGATGCCCTCGACATCGACCTGGTAAAGCTCGCGCGTTTTGCAGGCGCGCGG
CTGATCTTGGGAGCCGCTGAAGAAATCGACCCGATCTCAAAGCGCATCACCGTGCCGGGACGACCCGCGATCGCCTATGA
CGTGGCCTCCATCGACATCGGCATAACATCGGCAATGCCAGAACTGGTGGGTTTTGACGATTTTGCCATTCCAGCCAAGC
CCCTGGGCAGGTTTGCAACCCGCTGGGATGCCTTTCGCAATGGCTCCGATCCGGCCCGCATCGCCTGCATCGGTGGCGGT
GTCGCTGGCGTAGAGCTGATCCTCGCAATGGCCCATGCGCTGCGCCAGCAGCAGCGACTGGCTCAGGCGACCCTGATCGA
TAGCGGATCTGTCCTTTCTGTGCTGACCTCGCAGAGCCAGACCCGCCTGCGCAAGGCGCTGGACGCCAACGGGGTACGCA
TCCTACAACAGACCCGGATCGACCACCTGAGCGCGGGTCGCATTCATCTTGAAGGCGGCCGGGTGATCGACAGCGATTTC
ACGGTTGGTGCAGCAGGCGCGCGCGCCTACGGCTGGCTTGAGACCTCGGGCCTTCAGCAGCATGAGGGGGCGCTGGTCAT
CTCTGAAACGCTCCAGACGTCGGACCCGGATGTATTTGCCTGTGGCGATTGCGCTCATATGGCCTATGCGCCCCGACCCA
AGGCGGGCGTCTATGCCGTGCGTCAGGCTCCCGTGCTCTATCACAATCTCAAGGCGGTGCTTGGGGGCGGATCGCTGAAG
TCTTATCAGCCGCAAAAGGACTATCTGAAGCTCATTTCCATGGGCGATAAATCGGCGCTCGCGGATCGTGACGGGCGCAG
CTTTGCCGGTGGCCTCCTGTGGCGGTGGAAGGATCACATCGACCGCAAATTTATGGGCAAGTTTTCCGCCCTGCCACAGA
TGCCCGCCCCCGCCCTGCCCCGCAGCCGCGCCAAAGGCATGGAGGCGGTGCTTGGGAGCAAACCCATGTGTGGGGGCTGT
GGCTCGAAAGTCGGGCGGCACGCGCTACACGCGGGGCTTGGTGCTTTTTCCGGTGCGCAACGCGCTGATGTGACGCCCCT
GCCGGGGGATGACGCCGCACAGCTCATGACGGGCAGCGCGACACAGGTCATCAGCACCGATCACTTGCGGGCCTTTACCG
AAGATCCGGTGGTGATGACTGCGATCGCCGCGCAACACGCGCTCAATGACATCTGGGCGATGGGAGCGCATCCACAGGCC
GCAACCGTAACCCTGATCCTGCCCCGCCAATCAGCGGACTTGCAGGAACGTCTGCTCGCCGAGATCATGCATAGCGCCCA
TCAGGAAATGACAGCCGCCGGCGCGGCCATCGTGGGCGGTCATACCTCTTTGGGTGAAGAACTCACCATTGGTTTTACCC
TGACCGGCCTATGCGAGACGCCCCCGTTGACGCTTGCGGGGGCGCAGGCGGGGGATCACCTGATCCTCACCAAACCGATT
GGCTCCGGCACGCTGATGGCAGCAGAGATGTCGGGCACAGCGCCGGGCGCCTGTGTGGCAGAGGCGCTTGATCTGATGTG
CCAGAGCCAGCGCGACGCCGCCACTGTTTTGCGCCCGGTGGCCCATGCGATGACGGATGTCACCGGCTTTGGCCTCTTGG
GGCATTTGCAGGGCCTCTGTGCGGCCTCCGACCTCGGAGCCGAAGTTGACTTTGATGCCATCCCGCTGATGGCGGGCGCT
GCGGCGCTTGCGGAGGCAGGTGTGCGCTCTACCATCTTCGAGGACAACGCGGCTCTTCTGCCAGGGATCGGCACAGCCGG
TGCGCGCGCGCTGCTCTTTGACCCGCAGACCTCGGGCGGGCTATTGGCCTCGGTTGATCCAGCGCGCGCATCCGACGCCC
TTCGTGAGTTGAAAAACCATGGCTATCACGCTGCAAAGATTGGAGAAATACGTGATGCAGACCAAGGTATCGTGATCCGT
TAG

Upstream 100 bases:

>100_bases
GCAAGCTCTGGGCGACGCACAACAAACCTGAACACCACACGGCCAGCAGCCCCGACGCCTAACGCAGGGGGCCGCGGCCC
GCGCCCCCCGGAGGCCCATG

Downstream 100 bases:

>100_bases
CAGGAGCGCTCTTGGCCCTCTAAGGCTCAGGATGCGTCGAGCAGCTCCAAGATCCGCTGAGCTGCCTGTTTGCGCGCGGC
CTCGTCAAGTCCCGTCAAGG

Product: AIR synthase related protein-like

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase [H]

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MHAPRLPLTRDLVLVGGGHTHALLLRMWGMKPLPGVRLTLINPGPTAPYSGMLPGFVAGHYTRDALDIDLVKLARFAGAR
LILGAAEEIDPISKRITVPGRPAIAYDVASIDIGITSAMPELVGFDDFAIPAKPLGRFATRWDAFRNGSDPARIACIGGG
VAGVELILAMAHALRQQQRLAQATLIDSGSVLSVLTSQSQTRLRKALDANGVRILQQTRIDHLSAGRIHLEGGRVIDSDF
TVGAAGARAYGWLETSGLQQHEGALVISETLQTSDPDVFACGDCAHMAYAPRPKAGVYAVRQAPVLYHNLKAVLGGGSLK
SYQPQKDYLKLISMGDKSALADRDGRSFAGGLLWRWKDHIDRKFMGKFSALPQMPAPALPRSRAKGMEAVLGSKPMCGGC
GSKVGRHALHAGLGAFSGAQRADVTPLPGDDAAQLMTGSATQVISTDHLRAFTEDPVVMTAIAAQHALNDIWAMGAHPQA
ATVTLILPRQSADLQERLLAEIMHSAHQEMTAAGAAIVGGHTSLGEELTIGFTLTGLCETPPLTLAGAQAGDHLILTKPI
GSGTLMAAEMSGTAPGACVAEALDLMCQSQRDAATVLRPVAHAMTDVTGFGLLGHLQGLCAASDLGAEVDFDAIPLMAGA
AALAEAGVRSTIFEDNAALLPGIGTAGARALLFDPQTSGGLLASVDPARASDALRELKNHGYHAAKIGEIRDADQGIVIR

Sequences:

>Translated_720_residues
MHAPRLPLTRDLVLVGGGHTHALLLRMWGMKPLPGVRLTLINPGPTAPYSGMLPGFVAGHYTRDALDIDLVKLARFAGAR
LILGAAEEIDPISKRITVPGRPAIAYDVASIDIGITSAMPELVGFDDFAIPAKPLGRFATRWDAFRNGSDPARIACIGGG
VAGVELILAMAHALRQQQRLAQATLIDSGSVLSVLTSQSQTRLRKALDANGVRILQQTRIDHLSAGRIHLEGGRVIDSDF
TVGAAGARAYGWLETSGLQQHEGALVISETLQTSDPDVFACGDCAHMAYAPRPKAGVYAVRQAPVLYHNLKAVLGGGSLK
SYQPQKDYLKLISMGDKSALADRDGRSFAGGLLWRWKDHIDRKFMGKFSALPQMPAPALPRSRAKGMEAVLGSKPMCGGC
GSKVGRHALHAGLGAFSGAQRADVTPLPGDDAAQLMTGSATQVISTDHLRAFTEDPVVMTAIAAQHALNDIWAMGAHPQA
ATVTLILPRQSADLQERLLAEIMHSAHQEMTAAGAAIVGGHTSLGEELTIGFTLTGLCETPPLTLAGAQAGDHLILTKPI
GSGTLMAAEMSGTAPGACVAEALDLMCQSQRDAATVLRPVAHAMTDVTGFGLLGHLQGLCAASDLGAEVDFDAIPLMAGA
AALAEAGVRSTIFEDNAALLPGIGTAGARALLFDPQTSGGLLASVDPARASDALRELKNHGYHAAKIGEIRDADQGIVIR
>Mature_720_residues
MHAPRLPLTRDLVLVGGGHTHALLLRMWGMKPLPGVRLTLINPGPTAPYSGMLPGFVAGHYTRDALDIDLVKLARFAGAR
LILGAAEEIDPISKRITVPGRPAIAYDVASIDIGITSAMPELVGFDDFAIPAKPLGRFATRWDAFRNGSDPARIACIGGG
VAGVELILAMAHALRQQQRLAQATLIDSGSVLSVLTSQSQTRLRKALDANGVRILQQTRIDHLSAGRIHLEGGRVIDSDF
TVGAAGARAYGWLETSGLQQHEGALVISETLQTSDPDVFACGDCAHMAYAPRPKAGVYAVRQAPVLYHNLKAVLGGGSLK
SYQPQKDYLKLISMGDKSALADRDGRSFAGGLLWRWKDHIDRKFMGKFSALPQMPAPALPRSRAKGMEAVLGSKPMCGGC
GSKVGRHALHAGLGAFSGAQRADVTPLPGDDAAQLMTGSATQVISTDHLRAFTEDPVVMTAIAAQHALNDIWAMGAHPQA
ATVTLILPRQSADLQERLLAEIMHSAHQEMTAAGAAIVGGHTSLGEELTIGFTLTGLCETPPLTLAGAQAGDHLILTKPI
GSGTLMAAEMSGTAPGACVAEALDLMCQSQRDAATVLRPVAHAMTDVTGFGLLGHLQGLCAASDLGAEVDFDAIPLMAGA
AALAEAGVRSTIFEDNAALLPGIGTAGARALLFDPQTSGGLLASVDPARASDALRELKNHGYHAAKIGEIRDADQGIVIR

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI15011844, Length=292, Percent_Identity=29.1095890410959, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI24797148, Length=289, Percent_Identity=28.0276816608997, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1788062, Length=328, Percent_Identity=34.7560975609756, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1787352, Length=370, Percent_Identity=27.027027027027, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17543426, Length=326, Percent_Identity=25.4601226993865, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653602, Length=301, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24653604, Length=301, Percent_Identity=27.906976744186, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28574119, Length=300, Percent_Identity=24, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 75335; Mature: 75335

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAPRLPLTRDLVLVGGGHTHALLLRMWGMKPLPGVRLTLINPGPTAPYSGMLPGFVAGH
CCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCC
YTRDALDIDLVKLARFAGARLILGAAEEIDPISKRITVPGRPAIAYDVASIDIGITSAMP
CCCCCHHHHHHHHHHHCCCEEEEECHHHCCHHHHEEECCCCCCEEEEEEEEEEEHHHHHH
ELVGFDDFAIPAKPLGRFATRWDAFRNGSDPARIACIGGGVAGVELILAMAHALRQQQRL
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
AQATLIDSGSVLSVLTSQSQTRLRKALDANGVRILQQTRIDHLSAGRIHLEGGRVIDSDF
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCEEECCCC
TVGAAGARAYGWLETSGLQQHEGALVISETLQTSDPDVFACGDCAHMAYAPRPKAGVYAV
CCCCCCCCCCCEEECCCCCCCCCCEEEEEHHCCCCCCEEEECCHHHCCCCCCCCCCEEEE
RQAPVLYHNLKAVLGGGSLKSYQPQKDYLKLISMGDKSALADRDGRSFAGGLLWRWKDHI
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCHHHCHHHHHHHHHH
DRKFMGKFSALPQMPAPALPRSRAKGMEAVLGSKPMCGGCGSKVGRHALHAGLGAFSGAQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
RADVTPLPGDDAAQLMTGSATQVISTDHLRAFTEDPVVMTAIAAQHALNDIWAMGAHPQA
CCCCCCCCCCCHHHHHCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ATVTLILPRQSADLQERLLAEIMHSAHQEMTAAGAAIVGGHTSLGEELTIGFTLTGLCET
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEEECCCC
PPLTLAGAQAGDHLILTKPIGSGTLMAAEMSGTAPGACVAEALDLMCQSQRDAATVLRPV
CCCEEECCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
AHAMTDVTGFGLLGHLQGLCAASDLGAEVDFDAIPLMAGAAALAEAGVRSTIFEDNAALL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCEEC
PGIGTAGARALLFDPQTSGGLLASVDPARASDALRELKNHGYHAAKIGEIRDADQGIVIR
CCCCCCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEC
>Mature Secondary Structure
MHAPRLPLTRDLVLVGGGHTHALLLRMWGMKPLPGVRLTLINPGPTAPYSGMLPGFVAGH
CCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCC
YTRDALDIDLVKLARFAGARLILGAAEEIDPISKRITVPGRPAIAYDVASIDIGITSAMP
CCCCCHHHHHHHHHHHCCCEEEEECHHHCCHHHHEEECCCCCCEEEEEEEEEEEHHHHHH
ELVGFDDFAIPAKPLGRFATRWDAFRNGSDPARIACIGGGVAGVELILAMAHALRQQQRL
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
AQATLIDSGSVLSVLTSQSQTRLRKALDANGVRILQQTRIDHLSAGRIHLEGGRVIDSDF
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCEEECCCC
TVGAAGARAYGWLETSGLQQHEGALVISETLQTSDPDVFACGDCAHMAYAPRPKAGVYAV
CCCCCCCCCCCEEECCCCCCCCCCEEEEEHHCCCCCCEEEECCHHHCCCCCCCCCCEEEE
RQAPVLYHNLKAVLGGGSLKSYQPQKDYLKLISMGDKSALADRDGRSFAGGLLWRWKDHI
CCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHCCCCCCHHHCHHHHHHHHHH
DRKFMGKFSALPQMPAPALPRSRAKGMEAVLGSKPMCGGCGSKVGRHALHAGLGAFSGAQ
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
RADVTPLPGDDAAQLMTGSATQVISTDHLRAFTEDPVVMTAIAAQHALNDIWAMGAHPQA
CCCCCCCCCCCHHHHHCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ATVTLILPRQSADLQERLLAEIMHSAHQEMTAAGAAIVGGHTSLGEELTIGFTLTGLCET
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEEECCCC
PPLTLAGAQAGDHLILTKPIGSGTLMAAEMSGTAPGACVAEALDLMCQSQRDAATVLRPV
CCCEEECCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
AHAMTDVTGFGLLGHLQGLCAASDLGAEVDFDAIPLMAGAAALAEAGVRSTIFEDNAALL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCCCCEEC
PGIGTAGARALLFDPQTSGGLLASVDPARASDALRELKNHGYHAAKIGEIRDADQGIVIR
CCCCCCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA