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The map label for this gene is aat

Identifier: 99081360

GI number: 99081360

Start: 1625590

End: 1626222

Strand: Direct

Name: aat

Synonym: TM1040_1519

Alternate gene names: 99081360

Gene position: 1625590-1626222 (Clockwise)

Preceding gene: 99081359

Following gene: 99081369

Centisome position: 50.78

GC content: 59.24

Gene sequence:

>633_bases
ATGACGCTCAGCGCTGATCTCCTGCTTCATGCTTACGCGAACGGCGTCTTCCCCATGGCGGAGAGCCGCGACGATCCAGA
GGTGTTCTGGGTCGATCCAAAGCGCCGTGGCATTCTGCCTTTGGACGGTTTTCGGATTTCTCGTTCTCTGGCCAAACGCC
TTCGCCGCGATGATTACAGCATCAGCGTAAACCGCGATTTTGCGGGCGTGGTGCAGGGGTGTGCCGATCGCGAAGAGACC
TGGATCAACGGTGAAATCTTTGACCGTTACCAAGAGCTGCATCACGACGGATTTGCTCACTCTCTCGAAGTCTGGATGGA
CGATGCGCTGGTGGGGGGCGTCTACGGCGTCTCACTTGGGGGCGCCTTTTTTGGCGAAAGCATGTTCTCGCGCCGGCGAG
ATGCCTCCAAGATTGCACTCGCCTATCTCGTGGATCGTCTGAACGCAGGCGGCTACATTCTATGTGACACCCAGTTCATC
ACGCCTCATCTGGCGTCTCTTGGGGGGCGGGAAATCAGCCGCGCGGCTTATCGCAGAAGGCTCGCCGAGGCGCTGGACCA
GCCGGGAGATTTCATCTCTCCCGCGCTCCCGTCACCTCAGGTGCTCTTGCAGCGCAGAACCCAGACGTCGTAA

Upstream 100 bases:

>100_bases
TGGAAAAATGGCTTGAAGCCAACCTTCAGGCCTGAGACATCTTTCTGGGGGCGGCGGTTTAAAACCTCCGCCCCTCTGCT
ACCCCGTGCTAGGCTAATCT

Downstream 100 bases:

>100_bases
CGGCGATGATCGAGTGCGTTGAGCGCGGGGCTCGATGCAATCATCCAACCATCAAAGAACACTTTGCCGTCCTGGCGATC
CCGGATCGTCAGATACGCAA

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTLSADLLLHAYANGVFPMAESRDDPEVFWVDPKRRGILPLDGFRISRSLAKRLRRDDYSISVNRDFAGVVQGCADREET
WINGEIFDRYQELHHDGFAHSLEVWMDDALVGGVYGVSLGGAFFGESMFSRRRDASKIALAYLVDRLNAGGYILCDTQFI
TPHLASLGGREISRAAYRRRLAEALDQPGDFISPALPSPQVLLQRRTQTS

Sequences:

>Translated_210_residues
MTLSADLLLHAYANGVFPMAESRDDPEVFWVDPKRRGILPLDGFRISRSLAKRLRRDDYSISVNRDFAGVVQGCADREET
WINGEIFDRYQELHHDGFAHSLEVWMDDALVGGVYGVSLGGAFFGESMFSRRRDASKIALAYLVDRLNAGGYILCDTQFI
TPHLASLGGREISRAAYRRRLAEALDQPGDFISPALPSPQVLLQRRTQTS
>Mature_209_residues
TLSADLLLHAYANGVFPMAESRDDPEVFWVDPKRRGILPLDGFRISRSLAKRLRRDDYSISVNRDFAGVVQGCADREETW
INGEIFDRYQELHHDGFAHSLEVWMDDALVGGVYGVSLGGAFFGESMFSRRRDASKIALAYLVDRLNAGGYILCDTQFIT
PHLASLGGREISRAAYRRRLAEALDQPGDFISPALPSPQVLLQRRTQTS

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=203, Percent_Identity=43.3497536945813, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_SILST (Q1GGG4)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613514.1
- ProteinModelPortal:   Q1GGG4
- SMR:   Q1GGG4
- STRING:   Q1GGG4
- GeneID:   4077075
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1519
- NMPDR:   fig|292414.1.peg.3380
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   IGESMFY
- PhylomeDB:   Q1GGG4
- ProtClustDB:   PRK00301
- BioCyc:   SSP292414:TM1040_1519-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 23538; Mature: 23407

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSADLLLHAYANGVFPMAESRDDPEVFWVDPKRRGILPLDGFRISRSLAKRLRRDDYS
CCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCE
ISVNRDFAGVVQGCADREETWINGEIFDRYQELHHDGFAHSLEVWMDDALVGGVYGVSLG
EEECCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GAFFGESMFSRRRDASKIALAYLVDRLNAGGYILCDTQFITPHLASLGGREISRAAYRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHH
LAEALDQPGDFISPALPSPQVLLQRRTQTS
HHHHHCCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
TLSADLLLHAYANGVFPMAESRDDPEVFWVDPKRRGILPLDGFRISRSLAKRLRRDDYS
CCCHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCE
ISVNRDFAGVVQGCADREETWINGEIFDRYQELHHDGFAHSLEVWMDDALVGGVYGVSLG
EEECCCHHHHHHHHCCCCHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GAFFGESMFSRRRDASKIALAYLVDRLNAGGYILCDTQFITPHLASLGGREISRAAYRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHH
LAEALDQPGDFISPALPSPQVLLQRRTQTS
HHHHHCCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA