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The map label for this gene is rutR [H]

Identifier: 99081340

GI number: 99081340

Start: 1605177

End: 1605788

Strand: Direct

Name: rutR [H]

Synonym: TM1040_1499

Alternate gene names: 99081340

Gene position: 1605177-1605788 (Clockwise)

Preceding gene: 99081332

Following gene: 99081344

Centisome position: 50.15

GC content: 56.21

Gene sequence:

>612_bases
ATGGCCTCAGACCGCAGCCCCACGAGAATTCAAAAACGAAACCGTGCCAATATCTTAGAGGCCGCTCTGGAAGTGTTTTC
CCAACATGGGTTTCGTGGCTCCACGGTAGATCAGGTGGCCACCGCCGCCGGTCTTTCAAAGCCCAATCTGCTCTATTATT
ACCCCTCAAAAGAAGCGATCTTTACAGAGCTTTTGTCAAAGCTTCTTGACGATTGGCTGGCGCCCTTGCATGAAATCGAC
CCGGATGGCGAACCGATGGAGGAAATCCTCGGCTATGTGCAGCGCAAATTGCTGATGAGTCAGAGCATGCCGCGCGAAAG
CCGTCTCTTTGCCAATGAGATCGTGCAAGGCGCACCGCGCATGATCGACACGCTTTCGACCGACCTGCGTGCGCTGGTGG
ACAAGACCGAACTGATTTTCCAGAACTGGATGGACGCCGGCAAGATCGCCCCGGTTCACCCGCGCCATCTGCTGTTTTCA
ATCTGGTCGCTCACGCAACACTACGCCGATTTCGAGGTCCAGGTGCAGGCGCTGATGACCCCCGAAGATCCGTTTGAGGC
CGCACCGGAGTTTCTCGACACGCTCTATCGCAGGATGTTGACCCCGCCCTGA

Upstream 100 bases:

>100_bases
GCGCGTCCTGATTTCAGGATAAGATTTTGGCTGCTTATGATATGAGCAATTTTCAAGCAGCTTCGCGACCTCTCACAGCA
AGAGAAAGAATCGGCACGAT

Downstream 100 bases:

>100_bases
TCCGATCCCCCGCGCCCTGGCCAGAAGACGGCTGGGTGCAGAGATCCTGTGCCTCGAACTGGCACCACCTCCCGAGATAG
ATCTGCCTGCGCAAGTCACT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: Rut operon repressor [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MASDRSPTRIQKRNRANILEAALEVFSQHGFRGSTVDQVATAAGLSKPNLLYYYPSKEAIFTELLSKLLDDWLAPLHEID
PDGEPMEEILGYVQRKLLMSQSMPRESRLFANEIVQGAPRMIDTLSTDLRALVDKTELIFQNWMDAGKIAPVHPRHLLFS
IWSLTQHYADFEVQVQALMTPEDPFEAAPEFLDTLYRRMLTPP

Sequences:

>Translated_203_residues
MASDRSPTRIQKRNRANILEAALEVFSQHGFRGSTVDQVATAAGLSKPNLLYYYPSKEAIFTELLSKLLDDWLAPLHEID
PDGEPMEEILGYVQRKLLMSQSMPRESRLFANEIVQGAPRMIDTLSTDLRALVDKTELIFQNWMDAGKIAPVHPRHLLFS
IWSLTQHYADFEVQVQALMTPEDPFEAAPEFLDTLYRRMLTPP
>Mature_202_residues
ASDRSPTRIQKRNRANILEAALEVFSQHGFRGSTVDQVATAAGLSKPNLLYYYPSKEAIFTELLSKLLDDWLAPLHEIDP
DGEPMEEILGYVQRKLLMSQSMPRESRLFANEIVQGAPRMIDTLSTDLRALVDKTELIFQNWMDAGKIAPVHPRHLLFSI
WSLTQHYADFEVQVQALMTPEDPFEAAPEFLDTLYRRMLTPP

Specific function: Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787249, Length=173, Percent_Identity=47.9768786127168, Blast_Score=174, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR019915
- InterPro:   IPR001647
- InterPro:   IPR013573 [H]

Pfam domain/function: PF08362 TetR_C_3; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23174; Mature: 23043

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDRSPTRIQKRNRANILEAALEVFSQHGFRGSTVDQVATAAGLSKPNLLYYYPSKEAI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCHHHH
FTELLSKLLDDWLAPLHEIDPDGEPMEEILGYVQRKLLMSQSMPRESRLFANEIVQGAPR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
MIDTLSTDLRALVDKTELIFQNWMDAGKIAPVHPRHLLFSIWSLTQHYADFEVQVQALMT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCC
PEDPFEAAPEFLDTLYRRMLTPP
CCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASDRSPTRIQKRNRANILEAALEVFSQHGFRGSTVDQVATAAGLSKPNLLYYYPSKEAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECCHHHH
FTELLSKLLDDWLAPLHEIDPDGEPMEEILGYVQRKLLMSQSMPRESRLFANEIVQGAPR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
MIDTLSTDLRALVDKTELIFQNWMDAGKIAPVHPRHLLFSIWSLTQHYADFEVQVQALMT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCC
PEDPFEAAPEFLDTLYRRMLTPP
CCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]