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The map label for this gene is yqaB [C]

Identifier: 99081301

GI number: 99081301

Start: 1560700

End: 1561389

Strand: Reverse

Name: yqaB [C]

Synonym: TM1040_1460

Alternate gene names: 99081301

Gene position: 1561389-1560700 (Counterclockwise)

Preceding gene: 99081302

Following gene: 99081300

Centisome position: 48.78

GC content: 63.19

Gene sequence:

>690_bases
ATGCCCGCGGGGTATCTCTTTGATATGGATGGGCTGCTCCTTGATACGGAGCGGCTCACGCTGGACGCCTTTCTCGATTG
CGCGCCGGAGTTCGATCTGGATCCCGGCGAGATGCGCGCGTTCTTCATGACCCTCATTGGCAGCGCCCGGACGCAGGGCG
AGGCCATGGTGCGCGACTTCATCGGGCCGGATCGCGATTTCGACGCACTTGATCTGGCCTGGCAGCACCACAGCCAGAGG
CGGCTTGCGGCGGGCATCCCCGTCAAGCCGACGGTCGCAGAGACGATCTCAGCCCTTCATGCATCTGGGGCGGTCATGGC
TGTTGTGACTTCGACATTTGGTGACAAGGCCCGCCATCACCTTGACCGAGCCGGGTTGTTGAGGTGTTTTCGGACCGTAA
TCGGCGGTGATGAGGTCCCTGCAAACAAACCGGATCCTGCACCTTATGTTCAGGCGGCAGAGCAGCTTGGCGTACCGCCC
CAGAACTGCGCGGCTTTTGAGGACAGCGACACAGGGATCACGGCGGCGGCGCGGGCAGGCTGTTTTGCAGTGCAAATCCC
GGATCTGCGCCCAAGCGCGCGGGCGTTTCCGGATGTTGGACAGCGTTTCGCGACGACCCTCACAGAGGCCGTCACCACCG
CTCAGGCCCACTTTCACCATGAGCGCCGTCGGCAGGGCCGCAGTCTCTGA

Upstream 100 bases:

>100_bases
GGTCTATCGCTTCGGTGATGGAAGAGCTCTGCCTGCCGCGTCGAACGCTGAATGAGAAAATGGCGAAATACGGCCTGCAG
CGCTCCGACTATCTCGGCTG

Downstream 100 bases:

>100_bases
CGTAAACCGGGATAGTTTTGCATCAAAACGCCGCTCCACGCCCCGGTCTTAACCTTGCCTTTGAAATTTGCAGGCAAGGA
TGAAAATACCTCTCTCGGCG

Product: HAD family hydrolase

Products: glycolate; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPAGYLFDMDGLLLDTERLTLDAFLDCAPEFDLDPGEMRAFFMTLIGSARTQGEAMVRDFIGPDRDFDALDLAWQHHSQR
RLAAGIPVKPTVAETISALHASGAVMAVVTSTFGDKARHHLDRAGLLRCFRTVIGGDEVPANKPDPAPYVQAAEQLGVPP
QNCAAFEDSDTGITAAARAGCFAVQIPDLRPSARAFPDVGQRFATTLTEAVTTAQAHFHHERRRQGRSL

Sequences:

>Translated_229_residues
MPAGYLFDMDGLLLDTERLTLDAFLDCAPEFDLDPGEMRAFFMTLIGSARTQGEAMVRDFIGPDRDFDALDLAWQHHSQR
RLAAGIPVKPTVAETISALHASGAVMAVVTSTFGDKARHHLDRAGLLRCFRTVIGGDEVPANKPDPAPYVQAAEQLGVPP
QNCAAFEDSDTGITAAARAGCFAVQIPDLRPSARAFPDVGQRFATTLTEAVTTAQAHFHHERRRQGRSL
>Mature_228_residues
PAGYLFDMDGLLLDTERLTLDAFLDCAPEFDLDPGEMRAFFMTLIGSARTQGEAMVRDFIGPDRDFDALDLAWQHHSQRR
LAAGIPVKPTVAETISALHASGAVMAVVTSTFGDKARHHLDRAGLLRCFRTVIGGDEVPANKPDPAPYVQAAEQLGVPPQ
NCAAFEDSDTGITAAARAGCFAVQIPDLRPSARAFPDVGQRFATTLTEAVTTAQAHFHHERRRQGRSL

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1789046, Length=184, Percent_Identity=30.9782608695652, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789787, Length=172, Percent_Identity=27.906976744186, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082080, Length=184, Percent_Identity=28.804347826087, Blast_Score=60, Evalue=1e-10,
Organism=Drosophila melanogaster, GI17137324, Length=216, Percent_Identity=30.5555555555556, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116008157, Length=210, Percent_Identity=30.952380952381, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.18

Molecular weight: Translated: 24844; Mature: 24713

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGYLFDMDGLLLDTERLTLDAFLDCAPEFDLDPGEMRAFFMTLIGSARTQGEAMVRDF
CCCCCEEECCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
IGPDRDFDALDLAWQHHSQRRLAAGIPVKPTVAETISALHASGAVMAVVTSTFGDKARHH
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LDRAGLLRCFRTVIGGDEVPANKPDPAPYVQAAEQLGVPPQNCAAFEDSDTGITAAARAG
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCC
CFAVQIPDLRPSARAFPDVGQRFATTLTEAVTTAQAHFHHERRRQGRSL
EEEEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAGYLFDMDGLLLDTERLTLDAFLDCAPEFDLDPGEMRAFFMTLIGSARTQGEAMVRDF
CCCCEEECCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
IGPDRDFDALDLAWQHHSQRRLAAGIPVKPTVAETISALHASGAVMAVVTSTFGDKARHH
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LDRAGLLRCFRTVIGGDEVPANKPDPAPYVQAAEQLGVPPQNCAAFEDSDTGITAAARAG
HHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCC
CFAVQIPDLRPSARAFPDVGQRFATTLTEAVTTAQAHFHHERRRQGRSL
EEEEECCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phosphoglycolate; H2O

Specific reaction: 2-phosphoglycolate + H2O = glycolate + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]