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The map label for this gene is yhdH [H]

Identifier: 99081284

GI number: 99081284

Start: 1541561

End: 1542556

Strand: Reverse

Name: yhdH [H]

Synonym: TM1040_1443

Alternate gene names: 99081284

Gene position: 1542556-1541561 (Counterclockwise)

Preceding gene: 99081285

Following gene: 99081283

Centisome position: 48.19

GC content: 64.36

Gene sequence:

>996_bases
ATGTTCAAAGCCCTTGTTATGACGCAAGACAGCGAGAGCGGCAAAGCCGCTGCTGAAATTCAGGATCTGACCCTTGAGGA
TCTGCCGGAAGGAGAGGTCACGGTCGCCGTCTACTATTCCACCGTGAACTACAAGGATGGCCTGTGTCTCAGCCCCAAGG
GCGGCGGATTGGTGCGCAATTATCCGCATGTGCCGGGGATCGATTTTGCCGGCACCGTCGAGAGCTCCTCTGATGAGCGC
TACGCCCCGGGCGATAAGGTGGTCCTGACCGGCTGGCGCGTGGGCGAAGCCCATTGGGGCGGCTATGCACAAAAGGCCCG
TGTCAAGGCGGATTGGCTGGTGCCGCTGCCCGAAGGGATCACGCCCCGTCAGGCGATGGCCGTGGGCACTGCAGGCTTTA
CTGCGATGCTGGCGGTGATGGCGCTGGAGGATCACGGGCTGAAACCCGGAACGGGACCGGTTCTGGTCACAGGCGCGGCC
GGGGGCGTTGGCTCCGTGGCGACGGCGATCCTCGCCAACCTCGGTTACGAGGTGGCTGCCGTTACCGGGCGTCCCGAGAC
AGCCGACTACCTCCAGAGCCTCGGCGCAACCCAGATCGTGCCCCGCGAGGATCTGAACGAGACCGTAAAACGCCCGCTCG
AAAGCGAGACCTGGGCAGGCTGTGTCGACGCGGTCGGGGGGGATATGCTGGCGCGCGTGCTCGGGCAGATGAAATACGGT
GCCTCGGTTGCGGCCGTGGGGCTTGCGGGCGGTGCGGCTCTGCCGGCCACTGTGATTCCCTTCCTTCTGCGTGGTGTGAA
CCTCCTCGGCATCGATTCCGTGATGCAGCCCTTTGAGAACCGCCAGCGCGCTTGGCAGCGAATTGCCAGCGATCTGCCGC
TCGAAAAGCTCGACGCCATGATCCAGCCCGCATCACTGACCGACCTGCCAAAACTCGGCGCCGATATTCTGGCCGGGCAG
GTGAAGGGGCGCGTCGTCGTCGACGTCAACGCCTGA

Upstream 100 bases:

>100_bases
CGCATTGGGATGCGGGGACGCAGCTAGAGGTGGAGACACCGGATGGAATGCGTACTGCTCTGGTGCGCGAAAATTTCTGG
AATTAATGGGAGAGATCAAC

Downstream 100 bases:

>100_bases
GACCATGACATCCGAGTTCTGGCGCGGCGCGAAGTCGCGCCAGAGCGTTTCCGGGCTTGATCTTGGCGCTTGGAATTGCA
CTGTCTTTGCCAAGGCTGCA

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MFKALVMTQDSESGKAAAEIQDLTLEDLPEGEVTVAVYYSTVNYKDGLCLSPKGGGLVRNYPHVPGIDFAGTVESSSDER
YAPGDKVVLTGWRVGEAHWGGYAQKARVKADWLVPLPEGITPRQAMAVGTAGFTAMLAVMALEDHGLKPGTGPVLVTGAA
GGVGSVATAILANLGYEVAAVTGRPETADYLQSLGATQIVPREDLNETVKRPLESETWAGCVDAVGGDMLARVLGQMKYG
ASVAAVGLAGGAALPATVIPFLLRGVNLLGIDSVMQPFENRQRAWQRIASDLPLEKLDAMIQPASLTDLPKLGADILAGQ
VKGRVVVDVNA

Sequences:

>Translated_331_residues
MFKALVMTQDSESGKAAAEIQDLTLEDLPEGEVTVAVYYSTVNYKDGLCLSPKGGGLVRNYPHVPGIDFAGTVESSSDER
YAPGDKVVLTGWRVGEAHWGGYAQKARVKADWLVPLPEGITPRQAMAVGTAGFTAMLAVMALEDHGLKPGTGPVLVTGAA
GGVGSVATAILANLGYEVAAVTGRPETADYLQSLGATQIVPREDLNETVKRPLESETWAGCVDAVGGDMLARVLGQMKYG
ASVAAVGLAGGAALPATVIPFLLRGVNLLGIDSVMQPFENRQRAWQRIASDLPLEKLDAMIQPASLTDLPKLGADILAGQ
VKGRVVVDVNA
>Mature_331_residues
MFKALVMTQDSESGKAAAEIQDLTLEDLPEGEVTVAVYYSTVNYKDGLCLSPKGGGLVRNYPHVPGIDFAGTVESSSDER
YAPGDKVVLTGWRVGEAHWGGYAQKARVKADWLVPLPEGITPRQAMAVGTAGFTAMLAVMALEDHGLKPGTGPVLVTGAA
GGVGSVATAILANLGYEVAAVTGRPETADYLQSLGATQIVPREDLNETVKRPLESETWAGCVDAVGGDMLARVLGQMKYG
ASVAAVGLAGGAALPATVIPFLLRGVNLLGIDSVMQPFENRQRAWQRIASDLPLEKLDAMIQPASLTDLPKLGADILAGQ
VKGRVVVDVNA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789651, Length=329, Percent_Identity=53.1914893617021, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 34580; Mature: 34580

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKALVMTQDSESGKAAAEIQDLTLEDLPEGEVTVAVYYSTVNYKDGLCLSPKGGGLVRN
CCEEEEEECCCCCCCHHHHHHHCHHHCCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCC
YPHVPGIDFAGTVESSSDERYAPGDKVVLTGWRVGEAHWGGYAQKARVKADWLVPLPEGI
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHCEECEEEEEECCCCC
TPRQAMAVGTAGFTAMLAVMALEDHGLKPGTGPVLVTGAAGGVGSVATAILANLGYEVAA
CCHHHHEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
VTGRPETADYLQSLGATQIVPREDLNETVKRPLESETWAGCVDAVGGDMLARVLGQMKYG
ECCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
ASVAAVGLAGGAALPATVIPFLLRGVNLLGIDSVMQPFENRQRAWQRIASDLPLEKLDAM
CCEEEEECCCCCCCHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IQPASLTDLPKLGADILAGQVKGRVVVDVNA
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MFKALVMTQDSESGKAAAEIQDLTLEDLPEGEVTVAVYYSTVNYKDGLCLSPKGGGLVRN
CCEEEEEECCCCCCCHHHHHHHCHHHCCCCCCEEEEEEEEEECCCCCEEECCCCCCCCCC
YPHVPGIDFAGTVESSSDERYAPGDKVVLTGWRVGEAHWGGYAQKARVKADWLVPLPEGI
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHCEECEEEEEECCCCC
TPRQAMAVGTAGFTAMLAVMALEDHGLKPGTGPVLVTGAAGGVGSVATAILANLGYEVAA
CCHHHHEECCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEE
VTGRPETADYLQSLGATQIVPREDLNETVKRPLESETWAGCVDAVGGDMLARVLGQMKYG
ECCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
ASVAAVGLAGGAALPATVIPFLLRGVNLLGIDSVMQPFENRQRAWQRIASDLPLEKLDAM
CCEEEEECCCCCCCHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IQPASLTDLPKLGADILAGQVKGRVVVDVNA
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]