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The map label for this gene is sufS [H]

Identifier: 99081283

GI number: 99081283

Start: 1540223

End: 1541452

Strand: Reverse

Name: sufS [H]

Synonym: TM1040_1442

Alternate gene names: 99081283

Gene position: 1541452-1540223 (Counterclockwise)

Preceding gene: 99081284

Following gene: 99081282

Centisome position: 48.16

GC content: 60.33

Gene sequence:

>1230_bases
ATGAAACGCGCCATGGATATCGAATTTGTCCGCAAACAATTTCCGGCATTTGAACAGCCCTCTTTGCAGGGTCAGGCCTT
CTTTGAGAATGCAGGCGGCTCTTACACCTGCCGGCAGGTGATCGACCGCCTGTTTCGATTTTACACCGAGCATAAGGTCC
AGCCCTACGCGCCTTATGCCGCCTCCGAGGCAGCCGGCGCCGAGATGGATGAAGCGCGCAGTCGTCTGGCGGCGATGCTG
GGTGTCTCTGCGCAGGATCTGAGCTTCGGTCCTTCGACAACCCAGAATACCTATGTGCTGGCGCAGGCCTTCCGGGGCTT
CTTGAAGCCGGGCGAGAAGATCATCGTTACCAATCAGGACCATGAGGCCAACTCCGGCCCGTGGCGACGCTTGGCCGACG
AGGGCATCGAGGTGCTGGAGTGGCAGATCGATCCTGCCACCGGCCATCTTGAACCGAGCGCGCTGGAGGATCTCTTGGAC
GAGAGCGTGCGGCTGGTCTGTTTTCCCCATTGCTCCAATGTGGTGGGCGAGATCAATCCGGTCACGGAAATCACTGCGCT
GGCCCATGCTGCGGGGGCTTTTGTCTGCGTTGATGGCGTCTCTTACGCGCCGCATGGTTTGCCGAACGTGGGTGAACTGG
GGCCGGATATCTATTTGTTCTCCGCCTATAAAACCTATGGCCCTCATCAAGGGATCATGGTGATCAATCCCGCTCTTGCC
GAGCTTTTGCCCAATCAGGCGCACTACTTTAACGGGGATGTTCCTTACAAACGCTTCACCCCCGCCGGACCCGATCACGC
GCAGGTCGCCGCCTGTGCGGGAATGGTCGACTACTTCGAGGCGCTCGCCGAACATCACAACGCACCTGAGATCACAGGCA
CAGGGGCGGGCGCCTTTGTGCACGATCTGATGCGCGAGCAGGAGATCTCCTTGTTGCAGCCGCTCCTGGATGCGGTGAAG
GGGCGAAACGATGTGCGCTTGCTTGGCCCCGCGAACGCCAAAGAGCGTGCCCCGACCGTCGCGCTTGCGCTTGGGCGGGC
AGCAGAGCCCGTTGCCAAGCAATTGGCAGAGCTTGGGATCATGGCGGGGGGCAGCGACTTTTACGCAGTGCGTGCGCTCA
GGGCAATGGGGGTCGACCCCGCGCAGGGCGTGCTGCGGCTGAGTTTTACTCACTATACCGATCAATTGGAGGTGACAGCG
CTGATCGAGGCCCTAGATCGCGTCCTGTAA

Upstream 100 bases:

>100_bases
CATCCGAGTTCTGGCGCGGCGCGAAGTCGCGCCAGAGCGTTTCCGGGCTTGATCTTGGCGCTTGGAATTGCACTGTCTTT
GCCAAGGCTGCAAAGGGAGC

Downstream 100 bases:

>100_bases
AGACTGATCGAGCAAGGGATAAAACTGACCATGGCTGACACCCGACCGGTGATCTGGTGGATTCGGCGCGACCTGCGCCT
GCGCGACAATCCAGCCCTCA

Product: aminotransferase, class V

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MKRAMDIEFVRKQFPAFEQPSLQGQAFFENAGGSYTCRQVIDRLFRFYTEHKVQPYAPYAASEAAGAEMDEARSRLAAML
GVSAQDLSFGPSTTQNTYVLAQAFRGFLKPGEKIIVTNQDHEANSGPWRRLADEGIEVLEWQIDPATGHLEPSALEDLLD
ESVRLVCFPHCSNVVGEINPVTEITALAHAAGAFVCVDGVSYAPHGLPNVGELGPDIYLFSAYKTYGPHQGIMVINPALA
ELLPNQAHYFNGDVPYKRFTPAGPDHAQVAACAGMVDYFEALAEHHNAPEITGTGAGAFVHDLMREQEISLLQPLLDAVK
GRNDVRLLGPANAKERAPTVALALGRAAEPVAKQLAELGIMAGGSDFYAVRALRAMGVDPAQGVLRLSFTHYTDQLEVTA
LIEALDRVL

Sequences:

>Translated_409_residues
MKRAMDIEFVRKQFPAFEQPSLQGQAFFENAGGSYTCRQVIDRLFRFYTEHKVQPYAPYAASEAAGAEMDEARSRLAAML
GVSAQDLSFGPSTTQNTYVLAQAFRGFLKPGEKIIVTNQDHEANSGPWRRLADEGIEVLEWQIDPATGHLEPSALEDLLD
ESVRLVCFPHCSNVVGEINPVTEITALAHAAGAFVCVDGVSYAPHGLPNVGELGPDIYLFSAYKTYGPHQGIMVINPALA
ELLPNQAHYFNGDVPYKRFTPAGPDHAQVAACAGMVDYFEALAEHHNAPEITGTGAGAFVHDLMREQEISLLQPLLDAVK
GRNDVRLLGPANAKERAPTVALALGRAAEPVAKQLAELGIMAGGSDFYAVRALRAMGVDPAQGVLRLSFTHYTDQLEVTA
LIEALDRVL
>Mature_409_residues
MKRAMDIEFVRKQFPAFEQPSLQGQAFFENAGGSYTCRQVIDRLFRFYTEHKVQPYAPYAASEAAGAEMDEARSRLAAML
GVSAQDLSFGPSTTQNTYVLAQAFRGFLKPGEKIIVTNQDHEANSGPWRRLADEGIEVLEWQIDPATGHLEPSALEDLLD
ESVRLVCFPHCSNVVGEINPVTEITALAHAAGAFVCVDGVSYAPHGLPNVGELGPDIYLFSAYKTYGPHQGIMVINPALA
ELLPNQAHYFNGDVPYKRFTPAGPDHAQVAACAGMVDYFEALAEHHNAPEITGTGAGAFVHDLMREQEISLLQPLLDAVK
GRNDVRLLGPANAKERAPTVALALGRAAEPVAKQLAELGIMAGGSDFYAVRALRAMGVDPAQGVLRLSFTHYTDQLEVTA
LIEALDRVL

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=423, Percent_Identity=28.1323877068558, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789175, Length=428, Percent_Identity=26.8691588785047, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6319831, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 44361; Mature: 44361

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAMDIEFVRKQFPAFEQPSLQGQAFFENAGGSYTCRQVIDRLFRFYTEHKVQPYAPYA
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ASEAAGAEMDEARSRLAAMLGVSAQDLSFGPSTTQNTYVLAQAFRGFLKPGEKIIVTNQD
CCHHCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
HEANSGPWRRLADEGIEVLEWQIDPATGHLEPSALEDLLDESVRLVCFPHCSNVVGEINP
CCCCCCHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHCCCC
VTEITALAHAAGAFVCVDGVSYAPHGLPNVGELGPDIYLFSAYKTYGPHQGIMVINPALA
HHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHCCCCEEEEEEHHCCCCCCCEEEECHHHH
ELLPNQAHYFNGDVPYKRFTPAGPDHAQVAACAGMVDYFEALAEHHNAPEITGTGAGAFV
HHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
HDLMREQEISLLQPLLDAVKGRNDVRLLGPANAKERAPTVALALGRAAEPVAKQLAELGI
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCEEHHCCCCCHHHHHHHHHHE
MAGGSDFYAVRALRAMGVDPAQGVLRLSFTHYTDQLEVTALIEALDRVL
ECCCCHHHHHHHHHHHCCCHHCCEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRAMDIEFVRKQFPAFEQPSLQGQAFFENAGGSYTCRQVIDRLFRFYTEHKVQPYAPYA
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
ASEAAGAEMDEARSRLAAMLGVSAQDLSFGPSTTQNTYVLAQAFRGFLKPGEKIIVTNQD
CCHHCCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC
HEANSGPWRRLADEGIEVLEWQIDPATGHLEPSALEDLLDESVRLVCFPHCSNVVGEINP
CCCCCCHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHCCCC
VTEITALAHAAGAFVCVDGVSYAPHGLPNVGELGPDIYLFSAYKTYGPHQGIMVINPALA
HHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHCCCCEEEEEEHHCCCCCCCEEEECHHHH
ELLPNQAHYFNGDVPYKRFTPAGPDHAQVAACAGMVDYFEALAEHHNAPEITGTGAGAFV
HHCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
HDLMREQEISLLQPLLDAVKGRNDVRLLGPANAKERAPTVALALGRAAEPVAKQLAELGI
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHCCCCEEHHCCCCCHHHHHHHHHHE
MAGGSDFYAVRALRAMGVDPAQGVLRLSFTHYTDQLEVTALIEALDRVL
ECCCCHHHHHHHHHHHCCCHHCCEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA