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The map label for this gene is cdsA [H]

Identifier: 99081252

GI number: 99081252

Start: 1504970

End: 1505767

Strand: Reverse

Name: cdsA [H]

Synonym: TM1040_1411

Alternate gene names: 99081252

Gene position: 1505767-1504970 (Counterclockwise)

Preceding gene: 99081253

Following gene: 99081251

Centisome position: 47.04

GC content: 60.15

Gene sequence:

>798_bases
ATGAAAACACCTCTTAGCGCGCATGCCTCCAAGGCGAACCGTTGGGCCGATCTCGGACCGCGCACTGCCTCTGCGGTTGT
GCTGGCCCTGTTGGGCGGCGCTGCGATTTATCTCGGCAACCTTGCGTTTGCCCTGTTTGTGTCCCTGAGCGTGGGCGCGG
TTTTCTGGGAAGTCACCCGGATGTATCGTACCGATGGGAGCCTCCTTGCGCTTGGCTTTGGCGCGCTGGCTGCAGCTGCG
GTGTGCGTTGCGTCAATCGTGCCGCTGTTTCTCGCGCTCTTGGTTCTCGCGGTGCCGATGGTGGTAGGAACCCGCATCCT
CGAAGAGCGCAACCTCTCGTTTCTGGCGATCCTGGTCTGGGTGCTTCTTGGCGGTTTTGGACTGATTTGGATGCGTGAGG
GCATGGGAGTCACCTGGACCATCTGGCTGATTTCCGTCGTCGTTGCGACGGATGTGGCAGGGTACTTTGCTGGAAAGACG
TTCGGCGGACCGAAACTCTGGCCTGCCGTCAGCCCAAAGAAGACCTGGTCCGGCACCTCTGGCGGCTGGGGCGCTGCAGC
AGGCGTGGGGCTGGTCTTTGCGCTCTTTGTCGGTCTTCCCTGGAGCCTCGTTTGGATCTCGGTTTTTGTGTCGATGGCAA
GCCAGGCTGGTGACATCGTGGAAAGCGCGGTCAAACGCTACCGCAATGTCAAGGATTCAAGCCAGATCATCCCGGGCCAC
GGCGGTGTTTTTGACCGTTTTGATGGCATGCTGGGCGCTGGGGCACTCTGTTTCTTGATCGCCATCATCTGGGGATGA

Upstream 100 bases:

>100_bases
AGTTCATCGACACGCTGTGGCCCGATTTTTCATCCGAAGAACTGGCGCGCCTGTGTCGTAACTTCGGCAATCGAGACAGA
CGGTTCGGGGCCACCAAGAA

Downstream 100 bases:

>100_bases
ACCTGCCCCAACGCGGGGCGCGGGGCGGGTGATGCATGGGGTCACTATGAAAAAGATATCGATTTTTGGGGCAACGGGAT
CAATCGGGCAGAGCACCATT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKTPLSAHASKANRWADLGPRTASAVVLALLGGAAIYLGNLAFALFVSLSVGAVFWEVTRMYRTDGSLLALGFGALAAAA
VCVASIVPLFLALLVLAVPMVVGTRILEERNLSFLAILVWVLLGGFGLIWMREGMGVTWTIWLISVVVATDVAGYFAGKT
FGGPKLWPAVSPKKTWSGTSGGWGAAAGVGLVFALFVGLPWSLVWISVFVSMASQAGDIVESAVKRYRNVKDSSQIIPGH
GGVFDRFDGMLGAGALCFLIAIIWG

Sequences:

>Translated_265_residues
MKTPLSAHASKANRWADLGPRTASAVVLALLGGAAIYLGNLAFALFVSLSVGAVFWEVTRMYRTDGSLLALGFGALAAAA
VCVASIVPLFLALLVLAVPMVVGTRILEERNLSFLAILVWVLLGGFGLIWMREGMGVTWTIWLISVVVATDVAGYFAGKT
FGGPKLWPAVSPKKTWSGTSGGWGAAAGVGLVFALFVGLPWSLVWISVFVSMASQAGDIVESAVKRYRNVKDSSQIIPGH
GGVFDRFDGMLGAGALCFLIAIIWG
>Mature_265_residues
MKTPLSAHASKANRWADLGPRTASAVVLALLGGAAIYLGNLAFALFVSLSVGAVFWEVTRMYRTDGSLLALGFGALAAAA
VCVASIVPLFLALLVLAVPMVVGTRILEERNLSFLAILVWVLLGGFGLIWMREGMGVTWTIWLISVVVATDVAGYFAGKT
FGGPKLWPAVSPKKTWSGTSGGWGAAAGVGLVFALFVGLPWSLVWISVFVSMASQAGDIVESAVKRYRNVKDSSQIIPGH
GGVFDRFDGMLGAGALCFLIAIIWG

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=121, Percent_Identity=39.6694214876033, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787677, Length=105, Percent_Identity=35.2380952380952, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 27850; Mature: 27850

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPLSAHASKANRWADLGPRTASAVVLALLGGAAIYLGNLAFALFVSLSVGAVFWEVTR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MYRTDGSLLALGFGALAAAAVCVASIVPLFLALLVLAVPMVVGTRILEERNLSFLAILVW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLLGGFGLIWMREGMGVTWTIWLISVVVATDVAGYFAGKTFGGPKLWPAVSPKKTWSGTS
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GGWGAAAGVGLVFALFVGLPWSLVWISVFVSMASQAGDIVESAVKRYRNVKDSSQIIPGH
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GGVFDRFDGMLGAGALCFLIAIIWG
CCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]