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The map label for this gene is speH [H]

Identifier: 99081229

GI number: 99081229

Start: 1482166

End: 1482672

Strand: Direct

Name: speH [H]

Synonym: TM1040_1388

Alternate gene names: 99081229

Gene position: 1482166-1482672 (Clockwise)

Preceding gene: 99081224

Following gene: 99081230

Centisome position: 46.3

GC content: 58.38

Gene sequence:

>507_bases
ATGTCGGACGCCAACCTCTTCCAACTGGGGATCGGTCTGGAGACAGGCGCCCATGAGGAAGATACCGCCCGCGGTGTACC
CACCGCTATTGTTAACTCTTTGGTCGAAGCCGACCGGGAGGATCACTTTATCCGTCGCGACGGCAAGGTCTTTGCCGGGA
CCCATCTGATCATCGAAGTGATGAAAGGCTCCGGACTGGATTGTCAGGCCCGGATCGAAGACGCGTTTCGCAAGATGGTC
GAGGTCTGCGGCGCAACCCTGCTGCATATCCATACCCATAAATTCTCGCCTCAGGGTGTGTCGGGTGTGGCCGTGCTCGC
CGAGAGCCACATCTCTGTGCACACCTGGCCCGAGATCGGCTACGGCGCATTTGACGTCTTCATGTGTGGCGATGCACAGC
CTTGGAAAGCCGTCGATGTGCTAAAAGCCGCCTTTGAGACCGATGTGGTAGAAGTGCGCGAATTGCTGCGCGGCGAGGAA
ATCGTCGCCAAGGAGATCGCAGCATGA

Upstream 100 bases:

>100_bases
CTGCGCCTCACTTTCGGTACCGATCCCAACCCTGAACTCTTATTCGGGGGGGCGCTAAGGACCGTCTGGATTGTCATCTA
CTGGAACGAAGGGGAGTGTC

Downstream 100 bases:

>100_bases
CGAAAGAGGTCTGGAACACAGAACGCCTGCACGATCATTTCGCCCAATCCCTGCGCGTGAGCGAGATGTATTATGACAGC
AAGACCGAGCACCAGCGGCT

Product: S-adenosylmethionine decarboxylase related

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSDANLFQLGIGLETGAHEEDTARGVPTAIVNSLVEADREDHFIRRDGKVFAGTHLIIEVMKGSGLDCQARIEDAFRKMV
EVCGATLLHIHTHKFSPQGVSGVAVLAESHISVHTWPEIGYGAFDVFMCGDAQPWKAVDVLKAAFETDVVEVRELLRGEE
IVAKEIAA

Sequences:

>Translated_168_residues
MSDANLFQLGIGLETGAHEEDTARGVPTAIVNSLVEADREDHFIRRDGKVFAGTHLIIEVMKGSGLDCQARIEDAFRKMV
EVCGATLLHIHTHKFSPQGVSGVAVLAESHISVHTWPEIGYGAFDVFMCGDAQPWKAVDVLKAAFETDVVEVRELLRGEE
IVAKEIAA
>Mature_167_residues
SDANLFQLGIGLETGAHEEDTARGVPTAIVNSLVEADREDHFIRRDGKVFAGTHLIIEVMKGSGLDCQARIEDAFRKMVE
VCGATLLHIHTHKFSPQGVSGVAVLAESHISVHTWPEIGYGAFDVFMCGDAQPWKAVDVLKAAFETDVVEVRELLRGEEI
VAKEIAA

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 18282; Mature: 18151

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDANLFQLGIGLETGAHEEDTARGVPTAIVNSLVEADREDHFIRRDGKVFAGTHLIIEV
CCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCEEEHHHHHHHH
MKGSGLDCQARIEDAFRKMVEVCGATLLHIHTHKFSPQGVSGVAVLAESHISVHTWPEIG
HCCCCCCHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHEEECCCCEEEECCCCC
YGAFDVFMCGDAQPWKAVDVLKAAFETDVVEVRELLRGEEIVAKEIAA
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
SDANLFQLGIGLETGAHEEDTARGVPTAIVNSLVEADREDHFIRRDGKVFAGTHLIIEV
CCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCEEEHHHHHHHH
MKGSGLDCQARIEDAFRKMVEVCGATLLHIHTHKFSPQGVSGVAVLAESHISVHTWPEIG
HCCCCCCHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHEEECCCCEEEECCCCC
YGAFDVFMCGDAQPWKAVDVLKAAFETDVVEVRELLRGEEIVAKEIAA
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA