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The map label for this gene is ydcR [C]

Identifier: 99081227

GI number: 99081227

Start: 1480196

End: 1481611

Strand: Reverse

Name: ydcR [C]

Synonym: TM1040_1386

Alternate gene names: 99081227

Gene position: 1481611-1480196 (Counterclockwise)

Preceding gene: 99081228

Following gene: 99081226

Centisome position: 46.29

GC content: 60.88

Gene sequence:

>1416_bases
ATGGGTACAATTTGGCCCTCCACCCTGACCGGGTCCCTGACCGAAAAGCCGGGGCCCAAGTACAAGCGCGTGGCTGATAC
GATACGATTGGCGGTGGAGAGTGGTACATTGCAGGTGGGCGCAAAGCTGCCGCCTGTCCGCGAGCTCGCCTATCAGCTCA
GTATCACGCCTGGCACCGTCGCGCGGGCCTACACGATCCTGACAGACGAGGGCATCTTGCAGGCCGAGGTCGGACGCGGA
ACCTTTGTGGCCGAACGCGAAACGGCTGTGATGGATGACGTCTGGTCGCGGCAGTTGCATCTTCTTGAACGCAGCAACCC
CAATCACGTCTCTCTGTTCAGCCCGCGTCTTGTCGACGTGGGTCAAGTCAAGCTGATCCGCGAAGCGCTCCGAAAAGCCG
CTGATTGCGACCGCTTGGCGTTGTTGAATTATCCGACGCGCGACGCCTATCAGCCGGTGCGCCAAGCGGTTGTCGACTGG
CTATCCGATACCCCGCTCGGGCCACTGAGTGAGCGCGATGTGGTCTTGACCCATGGGGGCCAGAATGCCGTCATGACGGT
GATGCAAGCGATCCTGAAAGAGAGCAATCCCACCATCTTGGTCGAGGACCTCTCTTATGCCGGGTTCAGGCGCGCTGCAG
AGATCCTGCGTGCCAAAGTGGTCGGTGTTGCGATCGACGAAAACGGCATTGTGCCAGAGGCGTTGGAGGCTGCGATCAAG
AAATCGGGTGCATCTGTACTTTGTACCAGTCCCGAAGTGCACAATCCAACCGGCGCTTTTACCCCGCTTGAACGGCGCAA
AGAGATCCTCGCCATATTGAGACGACACAATGTACAATTGATCGAGGACGATTGTTATCGCATGGGGGAGGCCCGCGCGC
CGACCTATCGCGCGCTCGCGCCGGAGCTCAGCTGGCATGTGACATCGATTTCCAAATCGCTCACCCCGGCGCTGCGGGTG
GGGTTTGCAATCGCCCCCGTCGGCAAATCCGCAGATCTGCGCCGCGTTGCGGAATACGGTTTCTTTGGGCTTGCGCAGCC
GCTCGCCGAGGTGACACGCCTGCTATTGTCGGACCCGCGCAGCAAGAAGCTGGTCCAGACCGTGCGCGACGAGATGGCGG
AATATGTCCGTGTCGCCGTAAACGCCCTCGGAGCCTTTGAACTCACCTGGGACTCGCAGGTGCCGTTCCTTTGGCTGCGG
CTGCCTTCGGGCTGGCGAGCGGGTGCGTTTACACGTGCGGCCGAAGGGCAGGGGGTGCAACTGCGCTCTGCAGATGAGTT
TGCCCTGAGGGACGGGCGTGCGCCCAATGCAGTGCGCATCGCCGTCAATGGGCATGTCACGCTGGCGCGATTTGAGGATG
CCATGCTGCGTTTGCGCATGCTATTGGACAACCCACCAGAGCAAATCAGCGTCTGA

Upstream 100 bases:

>100_bases
TTTGTCATGGTCTGTCTCACATTTTGTATTGATGCAATTTGAATGTACTGGCATGTATTGAATACAAAGCGTGATACGGA
TTGTCTAAGCGGAGATTGTG

Downstream 100 bases:

>100_bases
GGGCATAATCGGCTCCAGATCATTGGGGTATTTTGATACCTATTTTGTAACCCCCTGTAATCAATGGGTTTTATGTGGTT
TGGCTGTATTGACTGTTGTG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MGTIWPSTLTGSLTEKPGPKYKRVADTIRLAVESGTLQVGAKLPPVRELAYQLSITPGTVARAYTILTDEGILQAEVGRG
TFVAERETAVMDDVWSRQLHLLERSNPNHVSLFSPRLVDVGQVKLIREALRKAADCDRLALLNYPTRDAYQPVRQAVVDW
LSDTPLGPLSERDVVLTHGGQNAVMTVMQAILKESNPTILVEDLSYAGFRRAAEILRAKVVGVAIDENGIVPEALEAAIK
KSGASVLCTSPEVHNPTGAFTPLERRKEILAILRRHNVQLIEDDCYRMGEARAPTYRALAPELSWHVTSISKSLTPALRV
GFAIAPVGKSADLRRVAEYGFFGLAQPLAEVTRLLLSDPRSKKLVQTVRDEMAEYVRVAVNALGAFELTWDSQVPFLWLR
LPSGWRAGAFTRAAEGQGVQLRSADEFALRDGRAPNAVRIAVNGHVTLARFEDAMLRLRMLLDNPPEQISV

Sequences:

>Translated_471_residues
MGTIWPSTLTGSLTEKPGPKYKRVADTIRLAVESGTLQVGAKLPPVRELAYQLSITPGTVARAYTILTDEGILQAEVGRG
TFVAERETAVMDDVWSRQLHLLERSNPNHVSLFSPRLVDVGQVKLIREALRKAADCDRLALLNYPTRDAYQPVRQAVVDW
LSDTPLGPLSERDVVLTHGGQNAVMTVMQAILKESNPTILVEDLSYAGFRRAAEILRAKVVGVAIDENGIVPEALEAAIK
KSGASVLCTSPEVHNPTGAFTPLERRKEILAILRRHNVQLIEDDCYRMGEARAPTYRALAPELSWHVTSISKSLTPALRV
GFAIAPVGKSADLRRVAEYGFFGLAQPLAEVTRLLLSDPRSKKLVQTVRDEMAEYVRVAVNALGAFELTWDSQVPFLWLR
LPSGWRAGAFTRAAEGQGVQLRSADEFALRDGRAPNAVRIAVNGHVTLARFEDAMLRLRMLLDNPPEQISV
>Mature_470_residues
GTIWPSTLTGSLTEKPGPKYKRVADTIRLAVESGTLQVGAKLPPVRELAYQLSITPGTVARAYTILTDEGILQAEVGRGT
FVAERETAVMDDVWSRQLHLLERSNPNHVSLFSPRLVDVGQVKLIREALRKAADCDRLALLNYPTRDAYQPVRQAVVDWL
SDTPLGPLSERDVVLTHGGQNAVMTVMQAILKESNPTILVEDLSYAGFRRAAEILRAKVVGVAIDENGIVPEALEAAIKK
SGASVLCTSPEVHNPTGAFTPLERRKEILAILRRHNVQLIEDDCYRMGEARAPTYRALAPELSWHVTSISKSLTPALRVG
FAIAPVGKSADLRRVAEYGFFGLAQPLAEVTRLLLSDPRSKKLVQTVRDEMAEYVRVAVNALGAFELTWDSQVPFLWLRL
PSGWRAGAFTRAAEGQGVQLRSADEFALRDGRAPNAVRIAVNGHVTLARFEDAMLRLRMLLDNPPEQISV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=173, Percent_Identity=29.4797687861272, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33469970, Length=173, Percent_Identity=29.4797687861272, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1787710, Length=442, Percent_Identity=26.4705882352941, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1790797, Length=351, Percent_Identity=25.0712250712251, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51803; Mature: 51672

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTIWPSTLTGSLTEKPGPKYKRVADTIRLAVESGTLQVGAKLPPVRELAYQLSITPGTV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCEEECCCCCHHHHHHEEEECCCCCH
ARAYTILTDEGILQAEVGRGTFVAERETAVMDDVWSRQLHLLERSNPNHVSLFSPRLVDV
HHEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
GQVKLIREALRKAADCDRLALLNYPTRDAYQPVRQAVVDWLSDTPLGPLSERDVVLTHGG
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
QNAVMTVMQAILKESNPTILVEDLSYAGFRRAAEILRAKVVGVAIDENGIVPEALEAAIK
CHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
KSGASVLCTSPEVHNPTGAFTPLERRKEILAILRRHNVQLIEDDCYRMGEARAPTYRALA
HCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCCHHHHC
PELSWHVTSISKSLTPALRVGFAIAPVGKSADLRRVAEYGFFGLAQPLAEVTRLLLSDPR
CCHHHHHHHHHHHHCHHHHHCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
SKKLVQTVRDEMAEYVRVAVNALGAFELTWDSQVPFLWLRLPSGWRAGAFTRAAEGQGVQ
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEEEEECCCCCCCCCEEECCCCCCEE
LRSADEFALRDGRAPNAVRIAVNGHVTLARFEDAMLRLRMLLDNPPEQISV
EECCCHHHHCCCCCCCEEEEEEECCEEEEHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
GTIWPSTLTGSLTEKPGPKYKRVADTIRLAVESGTLQVGAKLPPVRELAYQLSITPGTV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCEEECCCCCHHHHHHEEEECCCCCH
ARAYTILTDEGILQAEVGRGTFVAERETAVMDDVWSRQLHLLERSNPNHVSLFSPRLVDV
HHEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
GQVKLIREALRKAADCDRLALLNYPTRDAYQPVRQAVVDWLSDTPLGPLSERDVVLTHGG
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
QNAVMTVMQAILKESNPTILVEDLSYAGFRRAAEILRAKVVGVAIDENGIVPEALEAAIK
CHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
KSGASVLCTSPEVHNPTGAFTPLERRKEILAILRRHNVQLIEDDCYRMGEARAPTYRALA
HCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCCHHHHC
PELSWHVTSISKSLTPALRVGFAIAPVGKSADLRRVAEYGFFGLAQPLAEVTRLLLSDPR
CCHHHHHHHHHHHHCHHHHHCEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCC
SKKLVQTVRDEMAEYVRVAVNALGAFELTWDSQVPFLWLRLPSGWRAGAFTRAAEGQGVQ
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEEEEECCCCCCCCCEEECCCCCCEE
LRSADEFALRDGRAPNAVRIAVNGHVTLARFEDAMLRLRMLLDNPPEQISV
EECCCHHHHCCCCCCCEEEEEEECCEEEEHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1400197 [H]