Click here to switch to the map view.

The map label for this gene is mcpA [H]

Identifier: 99081224

GI number: 99081224

Start: 1476848

End: 1478965

Strand: Direct

Name: mcpA [H]

Synonym: TM1040_1383

Alternate gene names: 99081224

Gene position: 1476848-1478965 (Clockwise)

Preceding gene: 99081223

Following gene: 99081229

Centisome position: 46.14

GC content: 58.03

Gene sequence:

>2118_bases
ATGCGACTGCGATTGGTTATGCTGTTGGTCATTGGGCCAATGATGGCATTGTCGAGCTATCTTGCTTATGACGAGCTGCA
CATTCAGTGGGACAAATACGCACACGCAAGGTTAACCAAAGAGAAAACTCTCGAAGAATCCCTCATGAACGATGTGGTTC
ACGAGATGCAAAAAGAGCGCGGCTTCTCTGCCGGTTTCATCGCTTCGCAGGGCAAGAACTTCCCCACTGAACTCACGGAA
CAGCGGCGCCTCACCGACGAAGCCATTGCAGACTCCATGTCGCGGATTCCGGTGATTGAGGTCGCTAAACCGGACATGAC
CGCTGCGGTGCGCGAGCGGATCGGCCAGCTTCAGGATATGCGCCAACGCGTGGACAGCTTGGGCCTCTCGGTGCCTGAAA
TGGCCAAGTTCTACACCTCGACCATCGGCTTGATGCTTGAAATGGCGCGCCCAGCGACAGAGGGCGAGCCCGCAGAGCGG
CTGCGTCTTCTCGAAGAAGCTCGGGTCTTGCTCGCCTCAGCCAAGGAGGCCGCAGGGCTTGAGCGCGCTATGGGGGCAAC
CGGCCTCGGGAAAGGCTTTGACCTTGCGTTGCACGATCGCTTTGTCCACCTCGGCGGCGAACAGGGGGCCTATCTCCACG
AGGTCGATGCGCTGGTAGATCTCAATGTGTGGTTGTCAGAACTGCTTTCGACCGATGCCTACAAAGAGATTGCAGAAACG
CGCAGCACGCTCGTGCGGGGATATTCCACCGGGGACTTCGGCGGGCTGACCGCAGGGGAGTGGTTTCAGATTTCAACGAA
CTGGATCAACACCTTGCGCGAACAAGAGATCGAGATTGGCGCCCTGATTGACAGAATTGCGACCGACATCGAAAGCAGTT
CCCAAACCGCGTTCCGCGCGTTTGCAGCCGTGACTCTGATTTCACTTCTGCTGGCGTTCAGCATTGCGGTTTATATGTTT
GGGCGTGTCATCAAACGCGTGGGCGAGCTCACCGATGTTGTCAAAGCCTTCACGCGTGGAGATTACAGCGTCTTTGTACA
GGGTATCGAAGGCAAGGATGAGCTCAGCGTCATGGCGCATGCAATCTATTCCTTCAAGCAAGAAACCCTCAAGACCCTGC
GCGAGGCCGAAGCGCTTGAGGCTGAGCAAGATAAGCGCAAAAAGGAACAGGATCACATCGTTGGCGAACTTCGCGGTGCC
TTCACGCGTCTTTCCGTGGGCGACCTGACGGTTGAATTCACCGAGCCCTTCCCCGAGGACTACGAAGATGTCCGCGCCGA
TTTCAATCAGACCATCGGTCGACTGCGTGAATCTATGGAGGAACTGGTCGATACAGCTGGCAGCCTCTGCACCGGTGCCG
CTGAAATCGACCAGGCGGCCAGCGATCTGTCACAGCGCACAGAGAGCCAGGCGGCCACGCTTGAGGAAACGGCGGCTGCG
CTCGAGGAAATGACGGCCAGCGTCAAATCCGCAGCAGATGGCGCCCGCAACGCAGAGCGCACCACCGAAGAGGCAAGATC
AGAAGCAACTCAGAGCGGCACTGTCGTAAAAGACGCGGTTGAGGCCATGTCCGAGATCGAAAAGGGTTCCCAGCAGATTG
CGCAGATCATCAGTGTGATCGACGACATCGCATTTCAGACAAATCTCCTTGCGTTGAATGCCGGCGTCGAAGCCGCGCGC
GCAGGCGAAGCCGGTCGTGGATTTGCTGTGGTGGCCTCCGAAGTCCGCGCCTTGGCGCTGCGTTCCTCGGATGCGGCAAT
GGAGATCAAATCGCTGATCGGCAACAGCTCCGAACAGGTGGAGCGTGGCGTGGATCTGGTGCGCCATGCAGGCGAGGCGC
TTGAGAGCATCGTTGGCCAGGTGACCCATATCTCGACGCTTGTCACCGAGATCACCAAAGGTGCGGTTGAACAGTCCACT
GGGCTCGAAGAGATCAACACAGGTGTGGTTCAGCTTGATCAGGTGACCCAGCAGAACGCCGCGATGGTCGAGGAAACTAC
TGCCGCCAGCAGCATCCTCAACTCCAACGCACGCCAGCTTGGCGAAATCGTCCAGCGTTTCAAGATCCGCGGCGACCAGG
CGGCGGACAATATGCCTCAGCTCTCGCGCGCTAGCTGA

Upstream 100 bases:

>100_bases
ATCCGCTGCCTTTTAATGATCGCCGCATTCCCGTTTCAGGATGAGTTAACCATCGCCTCCTAGATTGTTCTAAGTTTGCG
CTGTTTACGAGGATGAGTCT

Downstream 100 bases:

>100_bases
CCCTGCGCGCAGGTTCGCCTGCGACGGTGGACGCTATCCTACAACAGAAAAGGCCGCCCAAGAGGCGGCCTTTTGCGTAT
TCGTAAGTTCCGGAAGCTTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MRLRLVMLLVIGPMMALSSYLAYDELHIQWDKYAHARLTKEKTLEESLMNDVVHEMQKERGFSAGFIASQGKNFPTELTE
QRRLTDEAIADSMSRIPVIEVAKPDMTAAVRERIGQLQDMRQRVDSLGLSVPEMAKFYTSTIGLMLEMARPATEGEPAER
LRLLEEARVLLASAKEAAGLERAMGATGLGKGFDLALHDRFVHLGGEQGAYLHEVDALVDLNVWLSELLSTDAYKEIAET
RSTLVRGYSTGDFGGLTAGEWFQISTNWINTLREQEIEIGALIDRIATDIESSSQTAFRAFAAVTLISLLLAFSIAVYMF
GRVIKRVGELTDVVKAFTRGDYSVFVQGIEGKDELSVMAHAIYSFKQETLKTLREAEALEAEQDKRKKEQDHIVGELRGA
FTRLSVGDLTVEFTEPFPEDYEDVRADFNQTIGRLRESMEELVDTAGSLCTGAAEIDQAASDLSQRTESQAATLEETAAA
LEEMTASVKSAADGARNAERTTEEARSEATQSGTVVKDAVEAMSEIEKGSQQIAQIISVIDDIAFQTNLLALNAGVEAAR
AGEAGRGFAVVASEVRALALRSSDAAMEIKSLIGNSSEQVERGVDLVRHAGEALESIVGQVTHISTLVTEITKGAVEQST
GLEEINTGVVQLDQVTQQNAAMVEETTAASSILNSNARQLGEIVQRFKIRGDQAADNMPQLSRAS

Sequences:

>Translated_705_residues
MRLRLVMLLVIGPMMALSSYLAYDELHIQWDKYAHARLTKEKTLEESLMNDVVHEMQKERGFSAGFIASQGKNFPTELTE
QRRLTDEAIADSMSRIPVIEVAKPDMTAAVRERIGQLQDMRQRVDSLGLSVPEMAKFYTSTIGLMLEMARPATEGEPAER
LRLLEEARVLLASAKEAAGLERAMGATGLGKGFDLALHDRFVHLGGEQGAYLHEVDALVDLNVWLSELLSTDAYKEIAET
RSTLVRGYSTGDFGGLTAGEWFQISTNWINTLREQEIEIGALIDRIATDIESSSQTAFRAFAAVTLISLLLAFSIAVYMF
GRVIKRVGELTDVVKAFTRGDYSVFVQGIEGKDELSVMAHAIYSFKQETLKTLREAEALEAEQDKRKKEQDHIVGELRGA
FTRLSVGDLTVEFTEPFPEDYEDVRADFNQTIGRLRESMEELVDTAGSLCTGAAEIDQAASDLSQRTESQAATLEETAAA
LEEMTASVKSAADGARNAERTTEEARSEATQSGTVVKDAVEAMSEIEKGSQQIAQIISVIDDIAFQTNLLALNAGVEAAR
AGEAGRGFAVVASEVRALALRSSDAAMEIKSLIGNSSEQVERGVDLVRHAGEALESIVGQVTHISTLVTEITKGAVEQST
GLEEINTGVVQLDQVTQQNAAMVEETTAASSILNSNARQLGEIVQRFKIRGDQAADNMPQLSRAS
>Mature_705_residues
MRLRLVMLLVIGPMMALSSYLAYDELHIQWDKYAHARLTKEKTLEESLMNDVVHEMQKERGFSAGFIASQGKNFPTELTE
QRRLTDEAIADSMSRIPVIEVAKPDMTAAVRERIGQLQDMRQRVDSLGLSVPEMAKFYTSTIGLMLEMARPATEGEPAER
LRLLEEARVLLASAKEAAGLERAMGATGLGKGFDLALHDRFVHLGGEQGAYLHEVDALVDLNVWLSELLSTDAYKEIAET
RSTLVRGYSTGDFGGLTAGEWFQISTNWINTLREQEIEIGALIDRIATDIESSSQTAFRAFAAVTLISLLLAFSIAVYMF
GRVIKRVGELTDVVKAFTRGDYSVFVQGIEGKDELSVMAHAIYSFKQETLKTLREAEALEAEQDKRKKEQDHIVGELRGA
FTRLSVGDLTVEFTEPFPEDYEDVRADFNQTIGRLRESMEELVDTAGSLCTGAAEIDQAASDLSQRTESQAATLEETAAA
LEEMTASVKSAADGARNAERTTEEARSEATQSGTVVKDAVEAMSEIEKGSQQIAQIISVIDDIAFQTNLLALNAGVEAAR
AGEAGRGFAVVASEVRALALRSSDAAMEIKSLIGNSSEQVERGVDLVRHAGEALESIVGQVTHISTLVTEITKGAVEQST
GLEEINTGVVQLDQVTQQNAAMVEETTAASSILNSNARQLGEIVQRFKIRGDQAADNMPQLSRAS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=278, Percent_Identity=46.0431654676259, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI2367378, Length=261, Percent_Identity=50.1915708812261, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1787690, Length=295, Percent_Identity=41.6949152542373, Blast_Score=205, Evalue=1e-53,
Organism=Escherichia coli, GI1788194, Length=255, Percent_Identity=47.0588235294118, Blast_Score=197, Evalue=3e-51,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=37.6, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76919; Mature: 76919

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRLVMLLVIGPMMALSSYLAYDELHIQWDKYAHARLTKEKTLEESLMNDVVHEMQKER
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFSAGFIASQGKNFPTELTEQRRLTDEAIADSMSRIPVIEVAKPDMTAAVRERIGQLQDM
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
RQRVDSLGLSVPEMAKFYTSTIGLMLEMARPATEGEPAERLRLLEEARVLLASAKEAAGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERAMGATGLGKGFDLALHDRFVHLGGEQGAYLHEVDALVDLNVWLSELLSTDAYKEIAET
HHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSTLVRGYSTGDFGGLTAGEWFQISTNWINTLREQEIEIGALIDRIATDIESSSQTAFRA
HHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FAAVTLISLLLAFSIAVYMFGRVIKRVGELTDVVKAFTRGDYSVFVQGIEGKDELSVMAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHH
AIYSFKQETLKTLREAEALEAEQDKRKKEQDHIVGELRGAFTRLSVGDLTVEFTEPFPED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
YEDVRADFNQTIGRLRESMEELVDTAGSLCTGAAEIDQAASDLSQRTESQAATLEETAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEMTASVKSAADGARNAERTTEEARSEATQSGTVVKDAVEAMSEIEKGSQQIAQIISVI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALALRSSDAAMEIKSLIGNSSEQV
HHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
ERGVDLVRHAGEALESIVGQVTHISTLVTEITKGAVEQSTGLEEINTGVVQLDQVTQQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHH
AMVEETTAASSILNSNARQLGEIVQRFKIRGDQAADNMPQLSRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLRLVMLLVIGPMMALSSYLAYDELHIQWDKYAHARLTKEKTLEESLMNDVVHEMQKER
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFSAGFIASQGKNFPTELTEQRRLTDEAIADSMSRIPVIEVAKPDMTAAVRERIGQLQDM
CCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
RQRVDSLGLSVPEMAKFYTSTIGLMLEMARPATEGEPAERLRLLEEARVLLASAKEAAGL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERAMGATGLGKGFDLALHDRFVHLGGEQGAYLHEVDALVDLNVWLSELLSTDAYKEIAET
HHHHCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSTLVRGYSTGDFGGLTAGEWFQISTNWINTLREQEIEIGALIDRIATDIESSSQTAFRA
HHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FAAVTLISLLLAFSIAVYMFGRVIKRVGELTDVVKAFTRGDYSVFVQGIEGKDELSVMAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHH
AIYSFKQETLKTLREAEALEAEQDKRKKEQDHIVGELRGAFTRLSVGDLTVEFTEPFPED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
YEDVRADFNQTIGRLRESMEELVDTAGSLCTGAAEIDQAASDLSQRTESQAATLEETAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEMTASVKSAADGARNAERTTEEARSEATQSGTVVKDAVEAMSEIEKGSQQIAQIISVI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DDIAFQTNLLALNAGVEAARAGEAGRGFAVVASEVRALALRSSDAAMEIKSLIGNSSEQV
HHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHH
ERGVDLVRHAGEALESIVGQVTHISTLVTEITKGAVEQSTGLEEINTGVVQLDQVTQQNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHH
AMVEETTAASSILNSNARQLGEIVQRFKIRGDQAADNMPQLSRAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]