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The map label for this gene is yafC [H]

Identifier: 99080960

GI number: 99080960

Start: 1202216

End: 1203121

Strand: Reverse

Name: yafC [H]

Synonym: TM1040_1119

Alternate gene names: 99080960

Gene position: 1203121-1202216 (Counterclockwise)

Preceding gene: 99080972

Following gene: 99080959

Centisome position: 37.59

GC content: 57.84

Gene sequence:

>906_bases
ATGGATTGGGACAAGCTCAGGATCTTTCACGCGGTTGCGGATGCAGGCAGCCTGACCCATGCGGGCGAACACCTCAACCT
GTCCCAATCGGCTGTTTCGCGGCAGATTCGGGGTCTTGAGGAGAGCCTGAACGCCACGCTTTTTCACCGGCACGCGCGGG
GGCTGATTCTCACCGAACAGGGCGAGCTGCTGTTTGACGCCACCAAAACGATGTCAAAACGTCTGGAAACCGCCTCGGCG
CGGATTCGCGACAGCGAAGAAGGCGTCTTTGGCGAGTTGCGCGTCACCACCACCACCGGATTTGGCACGCTCTGGCTCGC
GCCGCGTCTCATCAAGCTCTACGAGCAGTATCCCAACCTCAAAGTGGACCTGATGCTCGAAGAGCGGGTGCTGGATCTGC
CCATGCGCGAGGCCGATGTGGCGATCCGCATGAAAGAGCCAAGCCAGGCCGATCTCATTCGCAAACGCCTGATGACCGTG
CAGATGCGCCTCTATGCGTCCCGCGGCTATATCGACAAATTTGGCTGGCCCGAAACCATCGAGGAAATCCGCGATCACCG
CCTGATCTGCCAGAGCCTGCGTTCGGCGCAAGTCGGGTCCGCTGCGGTCATGGTGCAAAAGCTGATGACCCATAACCCCA
AATCCATGCTCACGGTGAACAACTATTTCGGCGTGTTACAGGGGGTTTTGCAGGATCTCGGCATCGGGGTTCTGCCGGAT
TACGTGACCGAGGATTTCCCGGATCTGGTGCAGGTTTTGCCCAATGAGGACACCAATGGTGTGCCGGTTTATCTCGCCTA
TCCAGAAGAATTGCGCCACTCGCAGCGGGTCTCCGCCTTCCGAGACTTTGTGCAGAATGAGATCATCGCACACCGTAAGC
ACATGAAAGAGCTTGGGAAAATATAA

Upstream 100 bases:

>100_bases
ATCCGATTGTTTAAAGTTTCGGTGTCAGCCTCCGGTAAGGTTTGAAACTTAGGTTCATCATCATGTAGTTTGGGGCAAAG
AGGCAGAAAGAGTAAAAACA

Downstream 100 bases:

>100_bases
CTTTCCCATCTACCTTCTGCGCCACGCGCAGGAGCTATGCACATAGCGCATGGCAGGCTTGATCCAACAAGGGTTTCAAA
ACACTTGCGGCAGCGCAGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MDWDKLRIFHAVADAGSLTHAGEHLNLSQSAVSRQIRGLEESLNATLFHRHARGLILTEQGELLFDATKTMSKRLETASA
RIRDSEEGVFGELRVTTTTGFGTLWLAPRLIKLYEQYPNLKVDLMLEERVLDLPMREADVAIRMKEPSQADLIRKRLMTV
QMRLYASRGYIDKFGWPETIEEIRDHRLICQSLRSAQVGSAAVMVQKLMTHNPKSMLTVNNYFGVLQGVLQDLGIGVLPD
YVTEDFPDLVQVLPNEDTNGVPVYLAYPEELRHSQRVSAFRDFVQNEIIAHRKHMKELGKI

Sequences:

>Translated_301_residues
MDWDKLRIFHAVADAGSLTHAGEHLNLSQSAVSRQIRGLEESLNATLFHRHARGLILTEQGELLFDATKTMSKRLETASA
RIRDSEEGVFGELRVTTTTGFGTLWLAPRLIKLYEQYPNLKVDLMLEERVLDLPMREADVAIRMKEPSQADLIRKRLMTV
QMRLYASRGYIDKFGWPETIEEIRDHRLICQSLRSAQVGSAAVMVQKLMTHNPKSMLTVNNYFGVLQGVLQDLGIGVLPD
YVTEDFPDLVQVLPNEDTNGVPVYLAYPEELRHSQRVSAFRDFVQNEIIAHRKHMKELGKI
>Mature_301_residues
MDWDKLRIFHAVADAGSLTHAGEHLNLSQSAVSRQIRGLEESLNATLFHRHARGLILTEQGELLFDATKTMSKRLETASA
RIRDSEEGVFGELRVTTTTGFGTLWLAPRLIKLYEQYPNLKVDLMLEERVLDLPMREADVAIRMKEPSQADLIRKRLMTV
QMRLYASRGYIDKFGWPETIEEIRDHRLICQSLRSAQVGSAAVMVQKLMTHNPKSMLTVNNYFGVLQGVLQDLGIGVLPD
YVTEDFPDLVQVLPNEDTNGVPVYLAYPEELRHSQRVSAFRDFVQNEIIAHRKHMKELGKI

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=29.2517006802721, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI145693193, Length=280, Percent_Identity=25.7142857142857, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789440, Length=292, Percent_Identity=27.0547945205479, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=27.906976744186, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789639, Length=304, Percent_Identity=22.6973684210526, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787128, Length=299, Percent_Identity=24.0802675585284, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI157672245, Length=222, Percent_Identity=28.8288288288288, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789173, Length=139, Percent_Identity=35.9712230215827, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787589, Length=285, Percent_Identity=24.5614035087719, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=171, Percent_Identity=26.9005847953216, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786448, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=176, Percent_Identity=27.8409090909091, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34312; Mature: 34312

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDKLRIFHAVADAGSLTHAGEHLNLSQSAVSRQIRGLEESLNATLFHRHARGLILTEQ
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
GELLFDATKTMSKRLETASARIRDSEEGVFGELRVTTTTGFGTLWLAPRLIKLYEQYPNL
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCC
KVDLMLEERVLDLPMREADVAIRMKEPSQADLIRKRLMTVQMRLYASRGYIDKFGWPETI
EEEEEEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EEIRDHRLICQSLRSAQVGSAAVMVQKLMTHNPKSMLTVNNYFGVLQGVLQDLGIGVLPD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCH
YVTEDFPDLVQVLPNEDTNGVPVYLAYPEELRHSQRVSAFRDFVQNEIIAHRKHMKELGK
HHHCCHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure
MDWDKLRIFHAVADAGSLTHAGEHLNLSQSAVSRQIRGLEESLNATLFHRHARGLILTEQ
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
GELLFDATKTMSKRLETASARIRDSEEGVFGELRVTTTTGFGTLWLAPRLIKLYEQYPNL
CCEEHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCC
KVDLMLEERVLDLPMREADVAIRMKEPSQADLIRKRLMTVQMRLYASRGYIDKFGWPETI
EEEEEEHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EEIRDHRLICQSLRSAQVGSAAVMVQKLMTHNPKSMLTVNNYFGVLQGVLQDLGIGVLPD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCCCCH
YVTEDFPDLVQVLPNEDTNGVPVYLAYPEELRHSQRVSAFRDFVQNEIIAHRKHMKELGK
HHHCCHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]